Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4J1G1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4J1G1-F1 | Predicted | AlphaFoldDB |
No variants for F4J1G1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for F4J1G1 | |||||
No associated diseases with F4J1G1
1 regional properties for F4J1G1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PRONE domain | 119 - 485 | IPR005512 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| guanyl-nucleotide exchange factor activity | Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9LZN0 | ROPGEF7 | Rop guanine nucleotide exchange factor 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVKASEKEHE | KYKPKLFDLE | NVKKKNSSSR | HFKRWNSDSA | LRIEDPDIDD | GTVFKKTATS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SIQPILPVLA | MDEQPQPREA | TDEESQKDSG | KREIISFLGY | NEKFTRDQVI | LRFRGLQAKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| CYFAYVTELE | QMKDKFAKLL | LGEDMSGGSK | GVSSALALSN | AITNLAASAF | GEIRRLEAIS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EDKKERWRRE | IGWLLSVTDH | IVEFSPTHQT | NEDGSSMEVM | TTKQRTDLVS | NIPSLKKLDE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MLLDCLDKFK | DQDEFYYVTP | GSPESENSNS | TRNDDKWWLP | IVKVPPKGLS | ETLKRFLLSQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RECVCQVLNS | AMAINSQVLT | EMEIPESYID | SLPKKGRASL | GDMIYRMITL | EMFDAEQFLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EMDLSSEHKI | LDLKNKFEAS | VVIWQRKIVQ | IDNKSSSPWS | TNLSMDKRQQ | LEERAATILQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LIKQEFPGIS | QSTLDISKIQ | FNRDIGLAIV | ESYSRILESL | AHTVMSRIED | VLEADQLTQN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PELAMCKIHI | VKETESPEKE | EEPNFCLLED | RPKKQKPTIS | LSEVMQWNIE | TNEPRKEKSD |
| 550 | 560 | 570 | |||
| KKLLTRVSSM | IMSNNKKTTY | LESLGTTRSP | TAGRYS |