Q9LYW5
Gene name |
LUL1 (RF370, At5g03200, F15A17_230, MOK16.11) |
Protein name |
Probable E3 ubiquitin-protein ligase LUL1 |
Names |
Probable RING-type E3 ubiquitin transferase LUL1, Protein LOG2-LIKE UBIQUITIN LIGASE 1, RING finger protein 370 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G03200 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LYW5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LYW5-F1 | Predicted | AlphaFoldDB |
56 variants for Q9LYW5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_761633_C_T | 12 | G>E | No | 1000Genomes | |
| tmp_5_761634_C_G | 12 | G>R | No | 1000Genomes | |
| ENSVATH03012910 | 15 | Q>R | No | 1000Genomes | |
| ENSVATH13895147 | 18 | N>D | No | 1000Genomes | |
| ENSVATH03012909 | 28 | L>P | No | 1000Genomes | |
| ENSVATH13895146 | 29 | E>K | No | 1000Genomes | |
| ENSVATH00603344 | 40 | V>A | No | 1000Genomes | |
| tmp_5_761537_A_T | 44 | L>Q | No | 1000Genomes | |
| tmp_5_761533_G_C | 45 | N>K | No | 1000Genomes | |
| tmp_5_761532_G_T | 46 | P>T | No | 1000Genomes | |
| ENSVATH00603342 | 55 | P>L | No | 1000Genomes | |
| ENSVATH03012908 | 57 | N>H | No | 1000Genomes | |
| ENSVATH13895145 | 62 | P>A | No | 1000Genomes | |
| tmp_5_761439_G_T | 77 | H>N | No | 1000Genomes | |
| tmp_5_761436_G_A | 78 | H>Y | No | 1000Genomes | |
| ENSVATH06913775 | 92 | H>P | No | 1000Genomes | |
| ENSVATH00603341 | 98 | I>L | No | 1000Genomes | |
| ENSVATH10521502 | 98 | I>T | No | 1000Genomes | |
| ENSVATH06913774 | 103 | T>P | No | 1000Genomes | |
| ENSVATH06913773 | 105 | V>I | No | 1000Genomes | |
| ENSVATH06913772 | 106 | H>Q | No | 1000Genomes | |
| tmp_5_761351_T_C,TA | 106 | H>R | No | 1000Genomes | |
| tmp_5_761337_T_A | 111 | T>S | No | 1000Genomes | |
| ENSVATH06913771 | 112 | I>V | No | 1000Genomes | |
| ENSVATH06913770 | 121 | K>E | No | 1000Genomes | |
| ENSVATH06913769 | 124 | T>R | No | 1000Genomes | |
| tmp_5_761295_G_A | 125 | L>F | No | 1000Genomes | |
| ENSVATH00603340 | 130 | E>A | No | 1000Genomes | |
| tmp_5_761264_A_C | 135 | L>R | No | 1000Genomes | |
| ENSVATH06913764 | 158 | D>V | No | 1000Genomes | |
| tmp_5_761054_G_A | 166 | T>I | No | 1000Genomes | |
| ENSVATH06913762 | 177 | D>V | No | 1000Genomes | |
| ENSVATH06913761 | 185 | K>N | No | 1000Genomes | |
| ENSVATH00603338 | 189 | S>P | No | 1000Genomes | |
| tmp_5_760950_CT_TT,C | 201 | D>N | No | 1000Genomes | |
| tmp_5_760920_C_G | 211 | D>H | No | 1000Genomes | |
| tmp_5_760917_C_T | 212 | V>I | No | 1000Genomes | |
| ENSVATH06913760 | 216 | A>S | No | 1000Genomes | |
| ENSVATH06913759 | 216 | A>V | No | 1000Genomes | |
| ENSVATH06913757 | 223 | P>S | No | 1000Genomes | |
| ENSVATH03012905 | 239 | V>A | No | 1000Genomes | |
| ENSVATH10521498 | 244 | E>G | No | 1000Genomes | |
| tmp_5_760815_C_G | 246 | G>R | No | 1000Genomes | |
| ENSVATH03012903 | 249 | K>N | No | 1000Genomes | |
| tmp_5_760790_T_G | 254 | K>T | No | 1000Genomes | |
| tmp_5_760770_T_C | 261 | K>E | No | 1000Genomes | |
| tmp_5_760769_T_C | 261 | K>R | No | 1000Genomes | |
| ENSVATH03012902 | 262 | R>M | No | 1000Genomes | |
| ENSVATH03012901 | 262 | R>S | No | 1000Genomes | |
| ENSVATH03012900 | 267 | L>R | No | 1000Genomes | |
| tmp_5_760737_T_C | 272 | I>V | No | 1000Genomes | |
| ENSVATH03012898 | 279 | S>C | No | 1000Genomes | |
| tmp_5_760692_C_G | 287 | V>L | No | 1000Genomes | |
| tmp_5_760667_G_A | 295 | T>I | No | 1000Genomes | |
| tmp_5_760516_C_G | 316 | Q>H | No | 1000Genomes | |
| ENSVATH03012892 | 337 | G>V | No | 1000Genomes |
No associated diseases with Q9LYW5
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| ubiquitin protein ligase activity | Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues. |
| ubiquitin-protein transferase activity | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8LA32 | LUL4 | Probable E3 ubiquitin-protein ligase LUL4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGNLISLIFC | CGRRQRSNIP | PAMETAPLEL | PPNRFVFAAV | PPYLNPNPNY | VDQYPGNCLP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PPVTEPPMLP | YNFNHLHHYP | PNSYQLPHPL | FHGGRYPILP | PPTYVHQKAV | TIRNDVNLKK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KTLTLIPDPE | NPNRLLVSFT | FDASMPGRIT | VVFFATEDAE | CNLRATKEDT | LPPITFDFGE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GLGQKFIQSS | GTGIDLTAFK | DSELFKEVDT | DVFPLAVKAE | ATPAEEGKSG | STNVQITQVV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YTKEKGEIKI | EVVKQILWVN | KRRYELLEIY | GIENTVDGSD | EGKECVVCLS | EPRDTTVLPC |
| 310 | 320 | 330 | |||
| RHMCMCSGCA | KALRFQTNLC | PVCRQPVEML | LEINKNG |