Q9LRP1
Gene name |
NPSN13 (At3g17440, MTO12.3) |
Protein name |
Novel plant SNARE 13 |
Names |
AtNPSN13 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G17440 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LRP1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LRP1-F1 | Predicted | AlphaFoldDB |
12 variants for Q9LRP1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH07964795 | 23 | R>L | No | 1000Genomes | |
| tmp_3_5971648_A_T | 66 | L>H | No | 1000Genomes | |
| ENSVATH05851047 | 78 | N>K | No | 1000Genomes | |
| tmp_3_5971034_G_A | 113 | L>F | No | 1000Genomes | |
| tmp_3_5971031_A_G | 114 | F>L | No | 1000Genomes | |
| ENSVATH02156434 | 143 | D>H | No | 1000Genomes | |
| tmp_3_5970607_C_T | 145 | G>E | No | 1000Genomes | |
| tmp_3_5970464_T_G | 165 | Q>H | No | 1000Genomes | |
| ENSVATH13936574 | 190 | H>Q | No | 1000Genomes | |
| tmp_3_5970115_C_A | 229 | V>L | No | 1000Genomes | |
| tmp_3_5969976_A_G | 248 | I>T | No | 1000Genomes | |
| tmp_3_5969919_T_G | 267 | D>A | No | 1000Genomes |
No associated diseases with Q9LRP1
8 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| ER to Golgi transport vesicle membrane | The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| late endosome membrane | The lipid bilayer surrounding a late endosome. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| SNARE complex | A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| SNAP receptor activity | Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion. |
| SNARE binding | Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| vesicle fusion | Fusion of the membrane of a transport vesicle with its target membrane. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9LNH6 | NPSN12 | Novel plant SNARE 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MASNLPMSPQ | LEQIHGEIRD | HFRALANGFQ | RLDKIKDSTR | QSKQLEELTD | KMRECKRLVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EFDRELKDEE | ARNSPEVNKQ | LNDEKQSMIK | ELNSYVALRK | TYMSTLGNKK | VELFDMGAGV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGEPTAEENV | QVASSMSNQE | LVDAGMKRMD | ETDQAIERSK | QVVEQTLEVG | TQTAANLKGQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TDQMGRVVNH | LDTIQFSIKK | ASQLVKEIGR | QVATDKCIMG | FLFLIVCGVV | AIIIVKIVNP |
| 250 | 260 | ||||
| NNKDIRDIPG | LAPPAQSRKL | LYLRNQDYM |