Q9FZ95

PR
Gene name
PUP3 (At1g28220, F3H9.12)
Protein name
Purine permease 3
Names
AtPUP3
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G28220
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

295-351 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FZ95

Entry ID Method Resolution Chain Position Source
AF-Q9FZ95-F1 Predicted AlphaFoldDB

29 variants for Q9FZ95

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH13986766 5 L>V No 1000Genomes
tmp_1_9861415_A_C 7 I>S No 1000Genomes
tmp_1_9861380_C_A 19 G>* No 1000Genomes
ENSVATH04656332 26 L>H No 1000Genomes
ENSVATH12200097 27 Y>C No 1000Genomes
tmp_1_9861343_C_T 31 G>D No 1000Genomes
tmp_1_9861193_A_T 81 I>N No 1000Genomes
tmp_1_9861185_C_T 84 V>I No 1000Genomes
tmp_1_9861153_G_T 94 N>K No 1000Genomes
ENSVATH01116269 116 Q>H No 1000Genomes
tmp_1_9861042_C_G 131 K>N No 1000Genomes
ENSVATH12200095 139 A>V No 1000Genomes
ENSVATH00048033 173 I>M No 1000Genomes
ENSVATH04656330 176 A>V No 1000Genomes
ENSVATH12200053 220 V>I No 1000Genomes
tmp_1_9860750_A_C 229 F>V No 1000Genomes
tmp_1_9860610_G_A 250 A>V No 1000Genomes
ENSVATH13986765 252 F>L No 1000Genomes
ENSVATH13986744 254 A>T No 1000Genomes
ENSVATH04656327 265 I>T No 1000Genomes
ENSVATH04656326 299 F>I No 1000Genomes
ENSVATH12200050 310 S>F No 1000Genomes
tmp_1_9860400_C_G 320 G>A No 1000Genomes
ENSVATH01116268 323 K>N No 1000Genomes
tmp_1_9860386_C_G 325 G>R No 1000Genomes
ENSVATH12200049 333 Q>L No 1000Genomes
tmp_1_9860334_G_A 342 S>F No 1000Genomes
tmp_1_9860311_C_T 350 E>K No 1000Genomes
ENSVATH07530248 351 C>S No 1000Genomes

No associated diseases with Q9FZ95

No regional properties for Q9FZ95

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FZ95

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

2 GO annotations of molecular function

Name Definition
purine nucleobase transmembrane transporter activity Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.
purine nucleoside transmembrane transporter activity Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
purine nucleobase transport The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9FZ96 PUP1 Purine permease 1 Arabidopsis thaliana (Mouse-ear cress) PR
Q94GB1 PUP2 Purine permease 2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVKALVIINC IILAIGNCGG PLIMRLYFNN GGKRIWFSTF LETAGFPVIF IPLLFSYITR
70 80 90 100 110 120
RRSNNVGDST SFFLIKPRLL IAAVIVGILS GFDNYLYAYG IAYLPVSTAA LIIASQLAFI
130 140 150 160 170 180
AIFSFFMVKH KFTPFTINAV VLLTVGAAVL GMHTETDKPV HETHKQYITG FLITVAAAVM
190 200 210 220 230 240
YAFILPLVEL AYQKAKQTMS YTLVLEFQLI LCLLASIVSV IGMFIAGDFK ALPKEAREFK
250 260 270 280 290 300
LGEALFYVVA VFSAIIWQGF FLGAIGLIFS TSSLVSGIMI SVLLPITEVL AVIFYHEKFQ
310 320 330 340 350
AEKGLSLALS LWGFVSYFYG EIKSGEDKRR IQQEESQETE QSSLSRPISE C