Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q94GB1

Entry ID Method Resolution Chain Position Source
AF-Q94GB1-F1 Predicted AlphaFoldDB

44 variants for Q94GB1

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05651248 2 K>N No 1000Genomes
ENSVATH05651246 10 I>K No 1000Genomes
ENSVATH07908736 13 I>L No 1000Genomes
tmp_2_14273220_C_T 16 A>T No 1000Genomes
ENSVATH13519995 40 P>S No 1000Genomes
ENSVATH13519983 47 G>S No 1000Genomes
ENSVATH13519982 52 F>I No 1000Genomes
ENSVATH01944707 54 P>L No 1000Genomes
ENSVATH13519981 57 L>F No 1000Genomes
ENSVATH13519980 62 R>H No 1000Genomes
ENSVATH01944706 64 R>C No 1000Genomes
ENSVATH13519979 83 I>L No 1000Genomes
ENSVATH05651242 92 V>M No 1000Genomes
tmp_2_14272975_G_T,A 97 Y>* No 1000Genomes
ENSVATH13519977 106 I>V No 1000Genomes
ENSVATH14582025 111 A>V No 1000Genomes
tmp_2_14272914_G_A 118 Q>* No 1000Genomes
ENSVATH05651239 140 N>K No 1000Genomes
tmp_2_14272844_G_A 141 A>V No 1000Genomes
ENSVATH05651238 143 V>L No 1000Genomes
tmp_2_14272833_G_A 145 L>F No 1000Genomes
tmp_2_14272797_C_A 157 D>Y No 1000Genomes
ENSVATH01944705 200 R>P No 1000Genomes
tmp_2_14272638_G_A 210 Q>* No 1000Genomes
ENSVATH01944704 211 M>I No 1000Genomes
ENSVATH05651232 222 L>V No 1000Genomes
ENSVATH05651230 235 H>N No 1000Genomes
ENSVATH05651229 235 H>R No 1000Genomes
tmp_2_14272560_C_T 236 A>T No 1000Genomes
ENSVATH05651228 237 L>F No 1000Genomes
tmp_2_14272556_A_G 237 L>S No 1000Genomes
tmp_2_14272120_C_T 251 D>N No 1000Genomes
ENSVATH01944701 254 L>H No 1000Genomes
ENSVATH05651221 256 E>A No 1000Genomes
tmp_2_14272074_G_A 266 T>M No 1000Genomes
tmp_2_14272071_G_A 267 A>V No 1000Genomes
tmp_2_14272056_G_A 272 A>V No 1000Genomes
ENSVATH05651218 292 M>I No 1000Genomes
tmp_2_14271978_G_C 298 P>R No 1000Genomes
tmp_2_14271945_T_G 309 Q>P No 1000Genomes
ENSVATH00258951 339 E>V No 1000Genomes
ENSVATH13519928 340 K>E No 1000Genomes
ENSVATH05651213 345 D>V No 1000Genomes
ENSVATH13519927 347 Q>E No 1000Genomes

No associated diseases with Q94GB1

No regional properties for Q94GB1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q94GB1

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

2 GO annotations of molecular function

Name Definition
purine nucleobase transmembrane transporter activity Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.
purine nucleoside transmembrane transporter activity Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
purine nucleobase transport The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9FZ95 PUP3 Purine permease 3 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FZ96 PUP1 Purine permease 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKMKTVLVII NCIFLAIGNC GGPLMMRLYF QNGGERIWFP SFLQTVGCPL IFFPLLLSFL
70 80 90 100 110 120
RRRRCLEEQE TTPFFLMKPP LFIAAIVVGL LVGFDNYLYS YGLAYIPVST ASLIISAQLG
130 140 150 160 170 180
FTALFAFFMV KQKFTPFTIN AIVLLTGGAV VLALNSDSDK LANETHKEYV VGFIMTLGAA
190 200 210 220 230 240
LLYGFILPLV ELSYKKSGQR ITYTLALEFQ MVLCFAATCV CLVGMLAAGD FKVKHALFIF
250 260 270 280 290 300
KNRVIAGEAR DFKLGESLYY VVIVFTAIIW QAFFVGAIGL IFCASSLVSG IMVSALLPVT
310 320 330 340 350
VILAVICFQE KFQAGKGVAL ALSLWGSVSY FYGQVKSEEK TKAQDTQLSQ LPVTDYVA