Q9FXA8
PR
Gene name |
INVA |
Protein name |
Alkaline/neutral invertase A, mitochondrial |
Names |
A/N-INVA |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G56560 |
EC number |
3.2.1.26: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FXA8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FXA8-F1 | Predicted | AlphaFoldDB |
59 variants for Q9FXA8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04979931 | 3 | A>G | No | 1000Genomes | |
| tmp_1_21192602_A_G | 4 | I>V | No | 1000Genomes | |
| ENSVATH00101460 | 5 | Y>H | No | 1000Genomes | |
| tmp_1_21192615_G_A | 8 | R>H | No | 1000Genomes | |
| ENSVATH13601347 | 9 | K>E | No | 1000Genomes | |
| ENSVATH01381338 | 23 | F>Y | No | 1000Genomes | |
| ENSVATH00101461 | 30 | D>E | No | 1000Genomes | |
| ENSVATH04979932 | 40 | S>L | No | 1000Genomes | |
| ENSVATH00101462 | 49 | R>I | No | 1000Genomes | |
| ENSVATH14334838 | 50 | F>L | No | 1000Genomes | |
| ENSVATH04979934 | 51 | V>I | No | 1000Genomes | |
| tmp_1_21192749_T_C | 53 | S>P | No | 1000Genomes | |
| tmp_1_21192752_T_A | 54 | S>T | No | 1000Genomes | |
| ENSVATH04979935 | 55 | I>T | No | 1000Genomes | |
| ENSVATH04979936 | 56 | Y>H | No | 1000Genomes | |
| ENSVATH13601349 | 58 | F>L | No | 1000Genomes | |
| ENSVATH04979937 | 60 | Q>H | No | 1000Genomes | |
| ENSVATH04979938 | 62 | K>N | No | 1000Genomes | |
| ENSVATH04979939 | 63 | I>V | No | 1000Genomes | |
| ENSVATH04979940 | 64 | L>I | No | 1000Genomes | |
| ENSVATH13601350 | 69 | S>A | No | 1000Genomes | |
| ENSVATH14334839 | 71 | K>N | No | 1000Genomes | |
| ENSVATH04979943 | 75 | I>V | No | 1000Genomes | |
| ENSVATH04979945 | 86 | T>I | No | 1000Genomes | |
| ENSVATH04979946 | 91 | K>E | No | 1000Genomes | |
| ENSVATH14334840 | 92 | S>I | No | 1000Genomes | |
| ENSVATH14334840 | 92 | S>N | No | 1000Genomes | |
| tmp_1_21192875_A_G | 95 | R>G | No | 1000Genomes | |
| ENSVATH13601351 | 96 | I>N | No | 1000Genomes | |
| ENSVATH14334841 | 98 | V>D | No | 1000Genomes | |
| tmp_1_21192899_A_G | 103 | I>V | No | 1000Genomes | |
| tmp_1_21192909_G_T | 106 | R>M | No | 1000Genomes | |
| ENSVATH13601353 | 114 | V>E | No | 1000Genomes | |
| ENSVATH13601352 | 114 | V>I | No | 1000Genomes | |
| tmp_1_21192957_A_G | 122 | E>G | No | 1000Genomes | |
| ENSVATH13601354 | 123 | K>E | No | 1000Genomes | |
| ENSVATH01381340 | 127 | E>K | No | 1000Genomes | |
| ENSVATH13601365 | 132 | E>D | No | 1000Genomes | |
| ENSVATH14334843 | 147 | C>Y | No | 1000Genomes | |
| tmp_1_21193052_G_C | 154 | V>L | No | 1000Genomes | |
| tmp_1_21193149_G_C | 186 | G>A | No | 1000Genomes | |
| ENSVATH13601367 | 209 | D>H | No | 1000Genomes | |
| tmp_1_21193390_G_A | 237 | V>I | No | 1000Genomes | |
| ENSVATH13601371 | 260 | I>V | No | 1000Genomes | |
| tmp_1_21193601_A_T | 282 | Q>L | No | 1000Genomes | |
| ENSVATH14334866 | 359 | A>S | No | 1000Genomes | |
| tmp_1_21194005_T_A | 386 | Y>N | No | 1000Genomes | |
| ENSVATH04979975 | 402 | P>S | No | 1000Genomes | |
| tmp_1_21194068_G_A | 407 | D>N | No | 1000Genomes | |
| ENSVATH13601398 | 450 | A>V | No | 1000Genomes | |
| tmp_1_21194320_A_T | 491 | T>S | No | 1000Genomes | |
| tmp_1_21194650_C_T | 518 | P>L | No | 1000Genomes | |
| ENSVATH04979998 | 527 | V>M | No | 1000Genomes | |
| ENSVATH13601400 | 530 | K>N | No | 1000Genomes | |
| ENSVATH01381351 | 534 | A>G | No | 1000Genomes | |
| ENSVATH13601401 | 579 | L>R | No | 1000Genomes | |
| tmp_1_21194916_G_A | 607 | V>I | No | 1000Genomes | |
| tmp_1_21194929_C_T | 611 | T>I | No | 1000Genomes | |
| tmp_1_21194937_C_G | 614 | L>V | No | 1000Genomes |
No associated diseases with Q9FXA8
No regional properties for Q9FXA8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9FXA8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.26 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycopeptide alpha-N-acetylgalactosaminidase activity | Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins. |
| sucrose alpha-glucosidase activity | Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| response to hydrogen peroxide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. |
| root development | The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo. |
| sucrose catabolic process | The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q10MC0 | NIN1 | Neutral/alkaline invertase 1, mitochondrial | Oryza sativa subsp japonica (Rice) | PR |
| Q84JL5 | INVH | Probable alkaline/neutral invertase A, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C560 | INVF | Probable alkaline/neutral invertase F | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4I2X9 | INVD | Probable alkaline/neutral invertase D | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LQF2 | CINV1 | Alkaline/neutral invertase CINV1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAIYLLRKI | STKTPSRFHR | SLFFSTFSKD | SPPDLSRTTS | IRHLSSSQRF | VSSSIYCFPQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SKILPNRFSE | KTTGISVRQF | STSVETNLSD | KSFERIHVQS | DAILERIHKN | EEEVETVSIG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SEKVVREESE | AEKEAWRILE | NAVVRYCGSP | VGTVAANDPG | DKMPLNYDQV | FIRDFVPSAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AFLLKGEGDI | VRNFLLHTLQ | LQSWEKTVDC | YSPGQGLMPA | SFKVRTVALD | ENTTEEVLDP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DFGESAIGRV | APVDSGLWWI | ILLRAYGKIT | GDFSLQERID | VQTGIKLIMN | LCLADGFDMF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PTLLVTDGSC | MIDRRMGIHG | HPLEIQSLFY | SALRCSREML | SVNDSSKDLV | RAINNRLSAL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SFHIREYYWV | DIKKINEIYR | YKTEEYSTDA | TNKFNIYPEQ | IPPWLMDWIP | EQGGYLLGNL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QPAHMDFRFF | TLGNFWSIVS | SLATPKQNEA | ILNLIEAKWD | DIIGNMPLKI | CYPALEYDDW |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RIITGSDPKN | TPWSYHNSGS | WPTLLWQFTL | ACMKMGRPEL | AEKALAVAEK | RLLADRWPEY |
| 550 | 560 | 570 | 580 | 590 | 600 |
| YDTRSGKFIG | KQSRLYQTWT | VAGFLTSKLL | LANPEMASLL | FWEEDYELLD | ICACGLRKSD |
| 610 | |||||
| RKKCSRVAAK | TQILVR |