Q9FV81
PR
Gene name |
GATB |
Protein name |
Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial |
Names |
Glu-AdT subunit B |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G48520 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FV81
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FV81-F1 | Predicted | AlphaFoldDB |
43 variants for Q9FV81
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04905718 | 26 | R>M | No | 1000Genomes | |
| ENSVATH13444686 | 37 | S>G | No | 1000Genomes | |
| tmp_1_17940294_G_T | 37 | S>I | No | 1000Genomes | |
| ENSVATH04905719 | 39 | T>K | No | 1000Genomes | |
| ENSVATH01321751 | 49 | S>P | No | 1000Genomes | |
| tmp_1_17940333_C_T | 50 | P>L | No | 1000Genomes | |
| ENSVATH00087603 | 50 | P>T | No | 1000Genomes | |
| tmp_1_17940354_A_C | 57 | N>T | No | 1000Genomes | |
| tmp_1_17940364_C_G | 60 | S>R | No | 1000Genomes | |
| tmp_1_17940365_A_T | 61 | N>Y | No | 1000Genomes | |
| ENSVATH13444687 | 91 | S>C | No | 1000Genomes | |
| tmp_1_17940465_A_G | 94 | N>S | No | 1000Genomes | |
| tmp_1_17940467_A_T | 95 | N>Y | No | 1000Genomes | |
| ENSVATH13444688 | 98 | S>A | No | 1000Genomes | |
| ENSVATH04905723 | 129 | L>F | No | 1000Genomes | |
| ENSVATH04905725 | 138 | S>Y | No | 1000Genomes | |
| ENSVATH04905729 | 174 | V>L | No | 1000Genomes | |
| tmp_1_17940726_G_A | 181 | G>D | No | 1000Genomes | |
| ENSVATH13444691 | 207 | G>V | No | 1000Genomes | |
| tmp_1_17941000_G_A | 232 | S>N | No | 1000Genomes | |
| tmp_1_17941287_A_T | 298 | D>V | No | 1000Genomes | |
| tmp_1_17941334_G_A | 314 | D>N | No | 1000Genomes | |
| ENSVATH04905747 | 317 | V>I | No | 1000Genomes | |
| tmp_1_17941468_A_C | 335 | K>T | No | 1000Genomes | |
| ENSVATH04905751 | 340 | A>S | No | 1000Genomes | |
| ENSVATH01321755 | 362 | S>C | No | 1000Genomes | |
| tmp_1_17941555_G_A | 364 | R>H | No | 1000Genomes | |
| ENSVATH13444732 | 365 | A>T | No | 1000Genomes | |
| tmp_1_17941558_C_T | 365 | A>V | No | 1000Genomes | |
| tmp_1_17941567_C_T | 368 | P>L | No | 1000Genomes | |
| tmp_1_17941599_G_C | 379 | E>Q | No | 1000Genomes | |
| ENSVATH13444733 | 380 | A>S | No | 1000Genomes | |
| ENSVATH13444734 | 395 | V>I | No | 1000Genomes | |
| ENSVATH13444735 | 396 | S>N | No | 1000Genomes | |
| tmp_1_17941842_G_A | 399 | E>K | No | 1000Genomes | |
| tmp_1_17941888_C_T | 414 | A>V | No | 1000Genomes | |
| tmp_1_17941952_T_A | 435 | D>E | No | 1000Genomes | |
| tmp_1_17942031_G_A | 462 | E>K | No | 1000Genomes | |
| tmp_1_17942273_T_A | 488 | D>E | No | 1000Genomes | |
| ENSVATH00087618 | 502 | E>D | No | 1000Genomes | |
| tmp_1_17942328_C_G | 507 | L>V | No | 1000Genomes | |
| ENSVATH13444764 | 508 | E>K | No | 1000Genomes | |
| tmp_1_17942514_C_A | 543 | L>M | No | 1000Genomes |
No associated diseases with Q9FV81
3 regional properties for Q9FV81
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast stroma | The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. |
| glutamyl-tRNA(Gln) amidotransferase complex | A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| glutaminyl-tRNAGln biosynthesis via transamidation | A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase. |
| mitochondrial translation | The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P33893 | PET112 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q2R2Z0 | GATB | Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial | Oryza sativa subsp japonica (Rice) | PR |
| C5Y3V8 | GATB | Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial | Sorghum bicolor (Sorghum) (Sorghum vulgare) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTTLLRTIQ | LNQFSLLGTS | LLRRRRSNNF | SVRSCGSQTT | TTHEAKQSSP | TRVAPKNHKS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NQLDEILRDY | EAVIGIETHV | QLSTLTKAFC | SCSNNYGSYP | NTSICPVCMG | LPGALPVLNS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KVVEFGVRLG | LALNCDLSLK | SKFDRKQYFY | PDLPKGYQIS | QFDIPIASGG | YVDVDIPLEF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GGGHRRFGIT | RVHMEEDAGK | LLHSDTGDYS | QVDLNRAGVP | LLEIVSEPDM | RSGIEAAEYA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CEMQRIARYL | GVSNGNMQEG | SLRCDVNISI | RPIGQAEFGT | KVEIKNLNAF | SAISRAIDFE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ISRQALLYNQ | GKADQIVTET | RLWEEGAQKT | VTMRKKEGLA | DYRYFPEPDL | PEVILTQEYV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DSIRASLPEL | PEAKRRRYEA | MGLGMQDVLF | LANDVSVAEY | FDAVIGKGAE | VKLAANWIMS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DIAAYLKNEK | LSINDIKLTP | QELAELIAAI | KDGTISGKIG | KEILFELLAK | GGTVKGMIKA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KDLVQITDPA | EIEKMVIQVV | SENPKQLEQY | RSGKTKLQGY | FAGQVMKMSK | GKANPGLLNK |
| ILLEKLNAKD |