Q9FS87

PR
Gene name
IVD (IVD2, PGSC0003DMG400008113)
Protein name
Isovaleryl-CoA dehydrogenase, mitochondrial
Names
IVD, Isovaleryl-CoA dehydrogenase 2, St-IVD2
Species
Solanum tuberosum (Potato)
KEGG Pathway
sot:102601763
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9FS87

Entry ID Method Resolution Chain Position Source
AF-Q9FS87-F1 Predicted AlphaFoldDB

No variants for Q9FS87

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9FS87

No associated diseases with Q9FS87

5 regional properties for Q9FS87

Type Name Position InterPro Accession
conserved_site Acyl-CoA dehydrogenase, conserved site 155 - 167 IPR006089-1
conserved_site Acyl-CoA dehydrogenase, conserved site 367 - 386 IPR006089-2
domain Acyl-CoA oxidase/dehydrogenase, middle domain 153 - 248 IPR006091
domain Acyl-CoA dehydrogenase/oxidase C-terminal 260 - 408 IPR009075
domain Acyl-CoA dehydrogenase/oxidase, N-terminal 36 - 149 IPR013786

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

3 GO annotations of molecular function

Name Definition
acyl-CoA dehydrogenase activity Catalysis of the reaction: acyl-CoA + oxidized
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
isovaleryl-CoA dehydrogenase activity Catalysis of the reaction: 3-methylbutanoyl-CoA + H+ + oxidized = 3-methyl-(2E)-butenoyl-CoA + reduced

3 GO annotations of biological process

Name Definition
3-methylbut-2-enoyl-CoA(4-) metabolic process The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-).
isovaleryl-CoA(4-) catabolic process The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-).
leucine catabolic process The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SWG0 IVD Isovaleryl-CoA dehydrogenase, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MHKLFVARSV KSALFRIKNH QKPQFAAFST SLLFDDTQKQ FKESVAQFAQ ENIAPHAEKI
70 80 90 100 110 120
DRTNYFPQDV NLWKLMGNFN LLGITVPEEY GGLGLGYLYH CIAMEEISRA SGSVGLSYGA
130 140 150 160 170 180
HTNLCINQLV RNGTHEQKQK YLPKLISGEH VGALAMSEPN AGSDVVSMKC KADRVEGGYV
190 200 210 220 230 240
LNGNKMWCTN GPTAQTLVVY AKTDVTAGSK GITAFIIEKG MTGFSTAQKL DKLGMRGSDT
250 260 270 280 290 300
CELVFENCFV PEENVLGQVG RGVYVLMSGL DLERLVLASG PVGIMQACLD VVLPYVKQRE
310 320 330 340 350 360
QFGRPIGEFQ FVQGKVADMY TSMQSSRSYL YSVARECDSG TINTKDCAGV ILSAAERATQ
370 380 390 400 410
VALQAIQCLG GNGYVNEYPT GRFLRDAKLY EIGAGTSEIR RMIIGRELFK EQ