Q9FMF8
Gene name |
DIT2-2 (At5g64280, MSJ1.12) |
Protein name |
Dicarboxylate transporter 2.2, chloroplastic |
Names |
AtpDCT2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G64280 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9FMF8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9FMF8-F1 | Predicted | AlphaFoldDB |
66 variants for Q9FMF8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH12925668 | 27 | A>S | No | 1000Genomes | |
| tmp_5_25713321_G_A | 31 | P>S | No | 1000Genomes | |
| tmp_5_25713304_G_T | 36 | H>Q | No | 1000Genomes | |
| ENSVATH07477088 | 37 | T>S | No | 1000Genomes | |
| tmp_5_25713291_G_A | 41 | L>F | No | 1000Genomes | |
| ENSVATH12925665 | 44 | L>F | No | 1000Genomes | |
| ENSVATH14647701 | 51 | F>V | No | 1000Genomes | |
| tmp_5_25713257_G_C,T | 52 | T>N | No | 1000Genomes | |
| tmp_5_25713257_G_C,T | 52 | T>S | No | 1000Genomes | |
| ENSVATH12925662 | 55 | A>T | No | 1000Genomes | |
| ENSVATH00750800 | 60 | L>S | No | 1000Genomes | |
| ENSVATH12925661 | 63 | E>K | No | 1000Genomes | |
| tmp_5_25713221_T_G | 64 | Q>P | No | 1000Genomes | |
| ENSVATH12925660 | 66 | K>E | No | 1000Genomes | |
| ENSVATH03473121 | 69 | P>L | No | 1000Genomes | |
| ENSVATH07477086 | 70 | P>L | No | 1000Genomes | |
| ENSVATH12925659 | 70 | P>T | No | 1000Genomes | |
| tmp_5_25713174_C_T | 80 | A>T | No | 1000Genomes | |
| ENSVATH12925656 | 82 | L>I | No | 1000Genomes | |
| ENSVATH12925655 | 86 | A>V | No | 1000Genomes | |
| ENSVATH14647699 | 100 | P>L | No | 1000Genomes | |
| ENSVATH12925653 | 111 | Q>H | No | 1000Genomes | |
| tmp_5_25713018_C_A | 132 | A>S | No | 1000Genomes | |
| ENSVATH07477085 | 134 | A>V | No | 1000Genomes | |
| ENSVATH07477084 | 139 | T>N | No | 1000Genomes | |
| ENSVATH07477082 | 158 | N>D | No | 1000Genomes | |
| ENSVATH07477081 | 187 | F>S | No | 1000Genomes | |
| tmp_5_25712805_C_T | 203 | A>T | No | 1000Genomes | |
| ENSVATH12925651 | 226 | P>A | No | 1000Genomes | |
| ENSVATH12925650 | 226 | P>L | No | 1000Genomes | |
| tmp_5_25712699_T_A | 238 | Y>F | No | 1000Genomes | |
| tmp_5_25712678_C_T | 245 | R>K | No | 1000Genomes | |
| ENSVATH12925648 | 247 | L>S | No | 1000Genomes | |
| ENSVATH07477077 | 283 | V>I | No | 1000Genomes | |
| tmp_5_25712404_T_G | 293 | T>P | No | 1000Genomes | |
| tmp_5_25712377_C_T | 302 | A>T | No | 1000Genomes | |
| tmp_5_25712372_A_C | 303 | F>L | No | 1000Genomes | |
| tmp_5_25712371_C_A | 304 | V>L | No | 1000Genomes | |
| ENSVATH12925626 | 311 | L>R | No | 1000Genomes | |
| ENSVATH12925624 | 336 | E>K | No | 1000Genomes | |
| ENSVATH14647698 | 339 | G>A | No | 1000Genomes | |
| ENSVATH00750798 | 346 | W>R | No | 1000Genomes | |
| ENSVATH12925623 | 351 | A>S | No | 1000Genomes | |
| tmp_5_25712205_C_G | 359 | W>S | No | 1000Genomes | |
| tmp_5_25712203_C_T | 360 | V>I | No | 1000Genomes | |
| ENSVATH12925615 | 393 | S>R | No | 1000Genomes | |
| ENSVATH07477069 | 408 | I>L | No | 1000Genomes | |
| ENSVATH00750797 | 411 | A>V | No | 1000Genomes | |
| ENSVATH12925594 | 418 | G>V | No | 1000Genomes | |
| ENSVATH12925593 | 425 | D>G | No | 1000Genomes | |
| ENSVATH00750796 | 426 | C>S | No | 1000Genomes | |
| ENSVATH00750795 | 444 | I>M | No | 1000Genomes | |
| ENSVATH07477067 | 453 | H>Q | No | 1000Genomes | |
| ENSVATH03473118 | 459 | Q>* | No | 1000Genomes | |
| tmp_5_25711705_G_A | 463 | A>V | No | 1000Genomes | |
| ENSVATH00750794 | 472 | A>T | No | 1000Genomes | |
| ENSVATH12925590 | 472 | A>V | No | 1000Genomes | |
| ENSVATH07477066 | 476 | A>T | No | 1000Genomes | |
| ENSVATH07477065 | 477 | A>G | No | 1000Genomes | |
| tmp_5_25711643_C_T | 484 | A>T | No | 1000Genomes | |
| tmp_5_25711640_C_T | 485 | A>T | No | 1000Genomes | |
| tmp_5_25711430_A_C | 517 | L>R | No | 1000Genomes | |
| tmp_5_25711413_C_T | 523 | V>I | No | 1000Genomes | |
| ENSVATH07477062 | 527 | M>I | No | 1000Genomes | |
| ENSVATH12925579 | 538 | V>I | No | 1000Genomes | |
| tmp_5_25711344_A_C | 546 | L>V | No | 1000Genomes |
No associated diseases with Q9FMF8
No regional properties for Q9FMF8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9FMF8 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| malate transmembrane transporter activity | Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9FMF7 | DIT2-1 | Dicarboxylate transporter 2.1, chloroplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MESLALRSIS | LSASYLSLHR | SSSKSFALLP | PSISVHTSPT | LRSLSISSPR | FTLRATASSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PEEQNKPQPP | PPSPPQPQGA | KLIPLAISVS | IGLIVRFLIP | RPEQVTSQGW | QLLSIFLFTI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGLVLGPLPV | GAWAFIGLTA | SIVTKTLPFS | TAFAAFTNEL | IWLIAISFFF | ARGFIKTGLG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DRIATYFVKW | LGKSTLGLSY | GLAFCETLMG | LIMPSTMARA | GGVFLPVIKS | LAISAGSYPG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DPSSRKLGSF | LIQTQLQCSG | ASGAILLTSA | AQNLLCLKLA | REVGVVISNP | WITWFKVASV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PAFVSLLCTP | LIIYKLYPPE | LKHTPEAPAA | AAKKLERLGP | ITKNEWIMLG | AMAFTVSLWV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FGEAIGIASV | VSAMIGLSTL | LLLGVINWDD | CLSDKSAWDS | LTWFAVLIGM | AGQLTNLGVV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AWMSDCVAKL | LQSLSLTWPA | SFIILQACYL | LIHYLFASQT | GHAGALYPPF | LAMQIAAGVP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GVLAALCLAF | NNNLSGALAH | YSGGPAALYY | GAGYVDLRDM | FRVGFVMALV | QAIIWGGVGS |
| FWWKFLGLY |