Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9FH32

Entry ID Method Resolution Chain Position Source
AF-Q9FH32-F1 Predicted AlphaFoldDB

100 variants for Q9FH32

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH07420741 4 N>T No 1000Genomes
tmp_5_22236714_A_G 31 C>R No 1000Genomes
tmp_5_22236662_G_A 48 S>F No 1000Genomes
tmp_5_22236490_C_G 67 D>H No 1000Genomes
ENSVATH03430578 108 G>V No 1000Genomes
ENSVATH07420733 113 M>L No 1000Genomes
tmp_5_22236324_G_A 122 S>F No 1000Genomes
tmp_5_22236236_G_C 151 N>K No 1000Genomes
ENSVATH07420731 156 T>S No 1000Genomes
ENSVATH07420729 158 A>P No 1000Genomes
ENSVATH07420729 158 A>S No 1000Genomes
tmp_5_22236196_C_T 165 V>I No 1000Genomes
ENSVATH03430576 169 K>R No 1000Genomes
ENSVATH07420728 170 S>T No 1000Genomes
ENSVATH12769963 173 Y>C No 1000Genomes
tmp_5_22236117_C_T 191 R>Q No 1000Genomes
ENSVATH03430571 210 E>D No 1000Genomes
tmp_5_22235968_A_C 211 M>R No 1000Genomes
ENSVATH12769958 211 M>V No 1000Genomes
ENSVATH07420722 222 C>F No 1000Genomes
ENSVATH07420722 222 C>Y No 1000Genomes
tmp_5_22235846_C_T 252 A>T No 1000Genomes
tmp_5_22235819_G_T 261 L>M No 1000Genomes
tmp_5_22235497_C_A 339 V>F No 1000Genomes
tmp_5_22235431_G_A 361 L>F No 1000Genomes
ENSVATH07420713 363 V>M No 1000Genomes
ENSVATH12769955 383 T>S No 1000Genomes
tmp_5_22235356_C_A 386 A>S No 1000Genomes
tmp_5_22235324_G_C 396 F>L No 1000Genomes
tmp_5_22235326_A_C 396 F>V No 1000Genomes
ENSVATH12769924 404 N>H No 1000Genomes
tmp_5_22235172_A_T 423 S>T No 1000Genomes
tmp_5_22235138_T_C 434 N>S No 1000Genomes
ENSVATH07420709 437 K>R No 1000Genomes
tmp_5_22235121_C_T 440 D>N No 1000Genomes
tmp_5_22235108_G_A 444 P>L No 1000Genomes
tmp_5_22235079_C_T 454 G>R No 1000Genomes
tmp_5_22235074_G_T 455 N>K No 1000Genomes
ENSVATH03430556 475 A>T No 1000Genomes
ENSVATH07420707 476 G>V No 1000Genomes
ENSVATH12769921 479 P>S No 1000Genomes
ENSVATH00734410 480 G>D No 1000Genomes
ENSVATH07420705 481 T>R No 1000Genomes
tmp_5_22234961_C_T 493 S>N No 1000Genomes
ENSVATH03430555 496 N>S No 1000Genomes
ENSVATH07420704 504 M>I No 1000Genomes
tmp_5_22234857_G_T 528 Q>K No 1000Genomes
tmp_5_22234847_A_G 531 V>A No 1000Genomes
ENSVATH07420703 533 H>Q No 1000Genomes
ENSVATH07420702 534 E>V No 1000Genomes
ENSVATH03430554 536 A>V No 1000Genomes
ENSVATH07420701 537 A>T No 1000Genomes
ENSVATH12769919 541 F>S No 1000Genomes
ENSVATH12769918 543 S>F No 1000Genomes
ENSVATH14632895 546 G>D No 1000Genomes
ENSVATH12769917 549 T>S No 1000Genomes
tmp_5_22234778_G_A 554 A>V No 1000Genomes
ENSVATH07420696 562 S>T No 1000Genomes
ENSVATH00734409 565 Q>E No 1000Genomes
ENSVATH07420692 602 V>A No 1000Genomes
tmp_5_22234635_C_G 602 V>L No 1000Genomes
ENSVATH07420691 608 V>I No 1000Genomes
ENSVATH07420690 613 T>I No 1000Genomes
ENSVATH00734408 617 V>E No 1000Genomes
ENSVATH00734407 620 R>C No 1000Genomes
ENSVATH14632894 641 W>R No 1000Genomes
ENSVATH12769891 665 R>G No 1000Genomes
tmp_5_22234363_C_T 666 E>K No 1000Genomes
tmp_5_22234358_C_T 667 M>I No 1000Genomes
tmp_5_22234357_C_T 668 E>K No 1000Genomes
ENSVATH00734406 678 E>A No 1000Genomes
tmp_5_22234314_C_A 682 R>I No 1000Genomes
tmp_5_22234313_T_G 682 R>S No 1000Genomes
ENSVATH12769888 697 Q>P No 1000Genomes
tmp_5_22234263_A_G 699 V>A No 1000Genomes
ENSVATH00734405 700 I>T No 1000Genomes
ENSVATH00734403 704 I>M No 1000Genomes
ENSVATH12769874 708 S>N No 1000Genomes
ENSVATH12769873 708 S>R No 1000Genomes
ENSVATH12769872 709 T>N No 1000Genomes
ENSVATH03430551 710 T>A No 1000Genomes
ENSVATH03430550 710 T>S No 1000Genomes
tmp_5_22234138_T_C 711 T>A No 1000Genomes
ENSVATH12769871 712 Q>E No 1000Genomes
ENSVATH03430549 714 D>N No 1000Genomes
ENSVATH00734402 718 T>P No 1000Genomes
ENSVATH12769870 719 L>P No 1000Genomes
tmp_5_22234111_C_T 720 E>K No 1000Genomes
tmp_5_22234101_C_T 723 G>E No 1000Genomes
ENSVATH00734401 729 G>R No 1000Genomes
ENSVATH07420681 735 E>G No 1000Genomes
ENSVATH07420682 735 E>K No 1000Genomes
ENSVATH15218025 742 V>L No 1000Genomes
ENSVATH03430548 745 E>K No 1000Genomes
ENSVATH12769867 752 N>S No 1000Genomes
ENSVATH07420680 754 S>N No 1000Genomes
ENSVATH07420680 754 S>T No 1000Genomes
ENSVATH07420679 760 E>D No 1000Genomes
tmp_5_22233984_A_C 762 V>G No 1000Genomes
ENSVATH07420678 762 V>L No 1000Genomes

No associated diseases with Q9FH32

No regional properties for Q9FH32

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9FH32

Functions

Description
EC Number
Subcellular Localization
  • Preautophagosomal structure membrane ; Peripheral membrane protein
  • Vacuole membrane ; Peripheral membrane protein
  • Peripheral membrane protein of pre-autophagosomal structure (PAS) and vacuole
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
response to starvation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H6U6 BCAS3 BCAS3 microtubule associated cell migration factor Homo sapiens (Human) PR
Q8CCN5 Bcas3 BCAS3 microtubule associated cell migration factor Mus musculus (Mouse) PR
10 20 30 40 50 60
MKKNGDGSSP KSPDGVVSRS ARSSFRALSN CLKVISSGAS TVARSAVSAA SSAVESHHDQ
70 80 90 100 110 120
VLWAGFDNLQ KEDGDTRRVL LLAFKSGFQV WDVEDTENVH VIVSAHDGQA FFMQMLLNPI
130 140 150 160 170 180
NSGVLDDRFY KSRPLLAVCG DYSSKKISSD NPGSETVATP TNVYVYSLKS QSYVHTLKFR
190 200 210 220 230 240
ATIYSVRCCS RIVAVLQAAQ IDCFDAATLE MDYRIVTNSI VCGSLGVGYG PLAVGPRWIA
250 260 270 280 290 300
YSGSRIATSS SAIFTSEIVS LSTSSPSVAQ FARDSSKQLA SGIANLGDKG YRSLTKYCSE
310 320 330 340 350 360
VLPNPYIPGL KGIGVGNEKV ADAESIGMVI VKDITNKSVI TQFKAHKSPI SALCFDQSGL
370 380 390 400 410 420
LLVTASIQGH NINVFRIMPT ISTSRAVKTT TFAHLFRLQR GFTNAVIQDI CFSKDSNLIV
430 440 450 460 470 480
VGSSRGTSHL FEINPEKEGD APVPMSAISR IRSGNSSGWI GTVSGAASAA AGMVAGSVPG
490 500 510 520 530 540
TVTSTFCYCD EKSNNNYYGS VADMCSKTNL LVFAPSGCMT QYALREHQVG VGHETAAMTG
550 560 570 580 590 600
FDSESGLETE GKLAVDPIRR WSMIQNQSRR ETHDPHSDIY GGGTSVDSKS KVFPEVVRKQ
610 620 630 640 650 660
SVEEAWKVSK KGTTRVVDKR HLYIYEAEQQ QTHLPTQLPL WARRKFRFQE LVLNRGEEIS
670 680 690 700 710 720
GGGGREMEIE GIQTRTIEAR TRDLVPVWGY LQSPRSQQVI NESIQSPSTT TQDDKVATLE
730 740 750 760
GHGTETDLGA VHSEEQTQSE PVDKEGIAEE KNHSEDEDEE QVD