Q9EP89
Gene name |
Lactb |
Protein name |
Serine beta-lactamase-like protein LACTB, mitochondrial |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:80907 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9EP89
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9EP89-F1 | Predicted | AlphaFoldDB |
27 variants for Q9EP89
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs243595741 | 13 | A>T | No | EVA | |
| rs237435219 | 31 | P>L | No | EVA | |
| rs231866540 | 76 | G>S | No | EVA | |
| rs387389700 | 88 | P>L | No | EVA | |
| rs387840413 | 110 | R>G | No | EVA | |
| rs3389048921 | 155 | E>D | No | EVA | |
| rs3400373069 | 193 | E>S | No | EVA | |
| rs3399962349 | 200 | E>WENRL* | No | EVA | |
| rs3400353259 | 241 | K>E | No | EVA | |
| rs3400085296 | 241 | K>T | No | EVA | |
| rs3400289218 | 243 | T>S | No | EVA | |
| rs3389054039 | 245 | P>Q | No | EVA | |
| rs222103345 | 247 | S>P | No | EVA | |
| rs3400324438 | 248 | D>Y | No | EVA | |
| rs3389055497 | 259 | K>Q | No | EVA | |
| rs3389054074 | 263 | K>R | No | EVA | |
| rs241235482 | 266 | A>T | No | EVA | |
| rs251723400 | 271 | V>A | No | EVA | |
| rs251723400 | 271 | V>G | No | EVA | |
| rs3389063037 | 280 | R>S | No | EVA | |
| rs3389000906 | 292 | E>* | No | EVA | |
| rs3389063100 | 320 | K>R | No | EVA | |
| rs3399738726 | 333 | T>G | No | EVA | |
| rs3389062200 | 443 | T>I | No | EVA | |
| rs3389063103 | 472 | E>K | No | EVA | |
| rs3389056127 | 494 | V>M | No | EVA | |
| rs33715056 | 508 | D>N | No | EVA |
No associated diseases with Q9EP89
1 regional properties for Q9EP89
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Luciferase-like domain | 1 - 320 | IPR011251 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
| peptidase activity | Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid metabolic process | The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
| regulation of lipid metabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P83111 | LACTB | Serine beta-lactamase-like protein LACTB, mitochondrial | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYRLLSSVTA | RAAATAGPAW | DGGRRGAHRR | PGLPVLGLGW | AGGLGLGLGL | ALGAKLVVGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RGAVPIQSPA | DPEASGTTEL | SHEQALSPGS | PHTPAPPAAR | GFSRAIESSR | DLLHRIKDEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GAPGIVVGVS | VDGKEVWSEG | LGYADVENRV | PCKPETVMRI | ASISKSLTMV | ALAKLWEAGK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDLDLPVQHY | VPEFPEKEYE | GEKVSVTTRL | LISHLSGIRH | YEKDIKKVKE | EKAYKALKMV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KGTPPPSDQE | KELKEKGGKN | NEKSDAPKAK | VEQDSEARCR | SAKPGKKKND | FEQGELYLKE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KFENSIESLR | LFKNDPLFFK | PGSQFLYSTF | GYTLLAAIVE | RASGYKYLDY | MQKIFHDLDM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LTTVQEENEP | VIYNRARFYV | YNKKKRLVNT | PYVDNSYKWA | GGGFLSTVGD | LLKFGNAMLY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GYQVGQFKNS | NENLLPGYLK | PETMVMMWTP | VPNTEMSWDK | EGKYAMAWGV | VEKKQTYGSC |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RKQRHYASHT | GGAVGASSVL | LVLPEELDSE | AVNNKVPPRG | IIVSIICNMQ | SVGLNSTALK |
| 550 | |||||
| IALEFDKDRA | D |