Q9DA80

PR
Gene name
Rsph3b (Rshl2, Rshl2b)
Protein name
Radial spoke head protein 3 homolog B
Names
A-kinase anchor protein RSPH3B, Radial spoke head-like protein 2B
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:100037282
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

46-128 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q9DA80

Entry ID Method Resolution Chain Position Source
8WZB EM 328 A D 1-389 PDB
8X2U EM 357 A D/L 1-389 PDB
AF-Q9DA80-F1 Predicted AlphaFoldDB

21 variants for Q9DA80

Variant ID(s) Position Change Description Diseaes Association Provenance
rs49582785 4 R>H No EVA
rs49582785 4 R>L No EVA
rs49582785 4 R>P No EVA
rs258884317 18 S>A No EVA
rs583558106 23 A>P No EVA
rs580193572 24 V>A No EVA
rs585754691 25 A>P No EVA
rs582277973 29 R>H No EVA
rs579447203 31 H>R No EVA
rs239528731 31 H>Y No EVA
rs220505444 32 R>G No EVA
rs3389432665 53 R>M No EVA
rs3407292576 272 K>N No EVA
rs3405594266 272 K>R No EVA
rs3407209239 278 F>Y No EVA
rs228557703 319 D>E No EVA
rs1134517975 335 P>L No EVA
rs1134115595 337 G>A No EVA
rs3407413123 359 T>M No EVA
rs1131694789 383 G>E No EVA
rs3389441432 384 G>E No EVA

No associated diseases with Q9DA80

No regional properties for Q9DA80

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9DA80

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, cilium axoneme
  • Cytoplasm, cytoskeleton, flagellum axoneme
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cilium A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3UFY4 Rsph3a Radial spoke head protein 3 homolog A Mus musculus (Mouse) PR
10 20 30 40 50 60
MTDRNPRTAE ASGLYTYSSR PRAVACQRRR HRDSILQPVE EPMSYGNIMY DRRVIRGNTY
70 80 90 100 110 120
ALPTGQVPGQ PDPLELQRQQ QARRRALARK RAQEQLKPRT PEPVEGRKHV DIQTELYLEE
130 140 150 160 170 180
IADRIVEVDM ECQTDAFLDR PPTPLFIPAK TGKDVATQIL GGELFDFDLE VKPMLEVLVG
190 200 210 220 230 240
KTIEQSLLEV MEEEELANLR ARQYAYEEIR NVELAEVQRL EEQERRHREE KERRKKQQWE
250 260 270 280 290 300
IVHKRNETLQ KISALIFARQ YLANLLPSVF DKLRNSGFFY DPIERDIEVG FLPWLMNEVE
310 320 330 340 350 360
KSMEHSMVGR TVLDMLIRDV VERRINDYEH KEAMPPGQKT NVINGPNTVT DPSVTTLHTQ
370 380
KPVLDRVSSQ PAPSQERKPV EEGGHLMAE