Q3UFY4
Gene name |
Rsph3a (Rshl2, Rshl2a) |
Protein name |
Radial spoke head protein 3 homolog A |
Names |
A-kinase anchor protein RSPH3A, Radial spoke head-like protein 2A |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:66832 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3UFY4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3UFY4-F1 | Predicted | AlphaFoldDB |
41 variants for Q3UFY4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs587182361 | 3 | A>S | No | EVA | |
| rs108196319 | 15 | R>P | No | EVA | |
| rs584264081 | 18 | H>L | No | EVA | |
| rs587031387 | 19 | Q>E | No | EVA | |
| rs581650131 | 22 | R>G | No | EVA | |
| rs578910156 | 30 | R>L | No | EVA | |
| rs581651596 | 67 | G>D | No | EVA | |
| rs3389447397 | 71 | P>S | No | EVA | |
| rs217592675 | 74 | L>P | No | EVA | |
| rs233233156 | 78 | L>P | No | EVA | |
| rs580277234 | 79 | R>* | No | EVA | |
| rs47877022 | 105 | A>S | No | EVA | |
| rs3389422942 | 106 | P>Q | No | EVA | |
| rs48511649 | 124 | Q>* | No | EVA | |
| rs48511649 | 124 | Q>K | No | EVA | |
| rs586603061 | 124 | Q>L | No | EVA | |
| rs46992488 | 131 | P>R | No | EVA | |
| rs586930554 | 145 | S>A | No | EVA | |
| rs579911570 | 150 | A>P | No | EVA | |
| rs582826231 | 151 | V>A | No | EVA | |
| rs586594605 | 152 | A>P | No | EVA | |
| rs585196258 | 158 | H>R | No | EVA | |
| rs580732643 | 158 | H>Y | No | EVA | |
| rs578995760 | 366 | W>R | No | EVA | |
| rs582379350 | 370 | H>R | No | EVA | |
| rs585603271 | 372 | R>Q | No | EVA | |
| rs1134459800 | 376 | L>S | No | EVA | |
| rs582981834 | 380 | S>* | No | EVA | |
| rs579874529 | 380 | S>P | No | EVA | |
| rs585447675 | 382 | L>R | No | EVA | |
| rs584019893 | 383 | I>T | No | EVA | |
| rs579731897 | 383 | I>V | No | EVA | |
| rs587511715 | 385 | A>T | No | EVA | |
| rs580012943 | 386 | R>Q | No | EVA | |
| rs583481843 | 393 | L>V | No | EVA | |
| rs586852979 | 396 | V>A | No | EVA | |
| rs580989365 | 398 | D>E | No | EVA | |
| rs586756305 | 399 | K>N | No | EVA | |
| rs582018432 | 446 | D>E | No | EVA | |
| rs3389434932 | 453 | N>D | No | EVA | |
| rs3389400322 | 473 | P>L | No | EVA |
No associated diseases with Q3UFY4
No regional properties for Q3UFY4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q3UFY4 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cilium | A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9DA80 | Rsph3b | Radial spoke head protein 3 homolog B | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAATNIWAAL | PAKKRPLHQR | ARRPAGGRGR | EPEVPFTTDP | SGNPAGRNCL | EFLPPGGTSG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CSATDGGATV | PLALRPFLRE | RRPLGSQHPC | PWHYLQVSDY | DDSLAPTCFR | AHLHRRGSSS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TLNQASAMTD | PNPRTAEASG | LYTYSSRPRA | VACQRRRHRD | SILQPVEEPM | SYGNIMYDRR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VIRGNTYALP | TGQVPGQPDP | LELQRQQQAR | RRALARKRAQ | EQLKPRTPEP | VEGRKHVDIQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TELYLEEIAD | RIVEVDMECQ | TDAFLDRPPT | PLFIPAKTGK | DVATQILGGE | LFDFDLEVKP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MLEVLVGKTI | EQSLLEVMEE | EELANLRARQ | YAYEEIRNVE | LAEVQRLEEQ | ERRHREEKER |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RKKQQWEIVH | KRNETLQKIS | ALIFARQYLA | NLLPSVFDKL | RNSGFFYDPI | ERDIEVGFLP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| WLMNEVEKSM | EHSMVGRTVL | DMLIRDVVER | RINDYEHKEA | MPPGQKTNVI | NGPNTVTDPS |
| 490 | 500 | 510 | |||
| VTTLHTQKPV | LDRVSSQPAP | SQERKPVEEG | GHLMAE |