Q9D2U5

PR
Gene name
Naa38 (Lsmd1)
Protein name
N-alpha-acetyltransferase 38, NatC auxiliary subunit
Names
LSM domain-containing protein 1
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:78304
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9D2U5

Entry ID Method Resolution Chain Position Source
AF-Q9D2U5-F1 Predicted AlphaFoldDB

4 variants for Q9D2U5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs13464584 66 C>S No EVA
rs3389145949 70 T>S No EVA
rs253198660 121 G>E No EVA
rs3389170003 125 L>F No EVA

No associated diseases with Q9D2U5

3 regional properties for Q9D2U5

Type Name Position InterPro Accession
domain Sm domain, eukaryotic/archaea-type 43 - 114 IPR001163
domain LSM domain containing 1, Sm domain 42 - 115 IPR034110
domain Sm domain 40 - 118 IPR047575

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
NatC complex A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
polysome A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
negative regulation of apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9BRA0 NAA38 N-alpha-acetyltransferase 38, NatC auxiliary subunit Homo sapiens (Human) PR
10 20 30 40 50 60
MAGAGPTMLL REENGCCSRR QSSSSAGDSD GEQEDSPATR ARQQLEALLN KTMRIRMTDG
70 80 90 100 110 120
RTLVGCFLCT DRDCNVILGS AQEFLKPSDS FSAGEPRVLG LAMVPGHHIV SIEVQRESLS
GGPYL