AiPD: Autoinhibited Protein Database

Gene name	Ecd
Protein name	Protein ecdysoneless homolog
Names
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:70601
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

387-641 (Predicted disordered autoinhibitory region) PR

387-641 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9CS74-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs245293589	71	V>A	No	EVA
rs3389236380	84	N>K	No	EVA
rs30704409	109	V>I	No	EVA
rs3389292540	111	D>E	No	EVA
rs3389301699	111	D>V	No	EVA
rs3389322037	112	N>S	No	EVA
rs13459391	123	D>N	No	EVA
rs3389236335	145	L>P	No	EVA
rs3389274619	161	P>R	No	EVA
rs242506523	182	L>S	No	EVA
rs213946591	195	V>I	No	EVA
rs3389264573	197	G>R	No	EVA
rs30704413	202	V>I	No	EVA
rs263752871	224	Q>R	No	EVA
rs3389316781	262	V>I	No	EVA
rs3389316750	279	P>S	No	EVA
rs245444231	286	G>R	No	EVA
rs225510187	288	P>L	No	EVA
rs3389310410	310	I>N	No	EVA
rs30706064	334	A>D	No	EVA
rs3389301679	353	S>Y	No	EVA
rs3412564285	385	E>K	No	EVA
rs3389316819	395	F>S	No	EVA
rs3389308030	396	D>Y	No	EVA
rs30706931	397	V>I	No	EVA
rs263354087	398	A>T	No	EVA
rs30706932	399	E>K	No	EVA
rs3389305599	399	E>V	No	EVA
rs3389236304	411	D>Y	No	EVA
rs3389292552	413	D>G	No	EVA
rs3389305541	430	A>T	No	EVA
rs3389322024	437	Q>H	No	EVA
rs3389321983	439	G>V	No	EVA
rs220861689	442	K>E	No	EVA
rs253263562	448	Y>H	No	EVA
rs3389264601	456	S>C	No	EVA
rs234484949	457	M>I	No	EVA
rs3389322045	458	K>N	No	EVA
rs30707830	479	A>V	No	EVA
rs3389305611	511	E>*	No	EVA
rs3389305820	513	D>G	No	EVA
rs3389321961	514	V>G	No	EVA
rs228069933	553	H>Q	No	EVA
rs3389282919	571	P>T	No	EVA
rs3389322026	583	D>E	No	EVA
rs30727554	585	G>S	No	EVA
rs3403405148	626	G>R	No	EVA
rs3389310433	632	N>Y	No	EVA
rs3389311733	634	D>V	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9CS74

		Description
EC Number
Subcellular Localization	Cytoplasm Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
histone acetyltransferase binding	Binding to an histone acetyltransferase.

Name	Definition
fibroblast proliferation	The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
mRNA processing	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
positive regulation of transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
RNA splicing	The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
O95905	ECD	Protein ecdysoneless homolog	Homo sapiens (Human)	PR