Q9CR57

PR
Gene name
Rpl14
Protein name
60S ribosomal protein L14
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:67115
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

165-217 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

6 structures for Q9CR57

Entry ID Method Resolution Chain Position Source
6SWA EM 310 A L 1-217 PDB
7CPU EM 282 A LM 1-217 PDB
7CPV EM 303 A LM 1-217 PDB
7LS1 EM 330 A G1 1-217 PDB
7LS2 EM 310 A G1 1-217 PDB
AF-Q9CR57-F1 Predicted AlphaFoldDB

5 variants for Q9CR57

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389063811 2 V>M No EVA
rs3389084035 13 A>T No EVA
rs3389051970 53 K>N No EVA
rs3401003388 69 R>L No EVA
rs30384543 182 A>V No EVA

No associated diseases with Q9CR57

2 regional properties for Q9CR57

Type Name Position InterPro Accession
domain Ribosomal protein L14e domain 47 - 120 IPR002784
domain Ribosomal protein L14, KOW motif 7 - 81 IPR041985

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
cytosolic ribosome A ribosome located in the cytosol.
postsynaptic density An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

3 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
ribosomal large subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P50914 RPL14 60S ribosomal protein L14 Homo sapiens (Human) PR
10 20 30 40 50 60
MVFRRYVEVG RVAYISFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF
70 80 90 100 110 120
ILKFPHSARQ KYVRKAWEKA DINTKWAATR WAKKIDARER KAKMTDFDRF KVMKAKKMRN
130 140 150 160 170 180
RIIKTEVKKL QRAAILKASP KKAAVAKAAI AAAAAAAAAK AKVPAKKATG PGKKAAGQKA
190 200 210
PAQKAAGQKA APPAKGQKGQ KTPAQKAPAP KAAGKKA