Q9CQ35
Gene name |
Glipr1l2 |
Protein name |
GLIPR1-like protein 2 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:67537 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9CQ35
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9CQ35-F1 | Predicted | AlphaFoldDB |
12 variants for Q9CQ35
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389099917 | 13 | A>V | No | EVA | |
| rs3389066567 | 17 | Y>N | No | EVA | |
| rs3389123430 | 21 | R>K | No | EVA | |
| rs3389114131 | 43 | P>T | No | EVA | |
| rs3389114160 | 48 | V>I | No | EVA | |
| rs227737216 | 91 | K>E | No | EVA | |
| rs3389123457 | 132 | R>I | No | EVA | |
| rs3389127334 | 138 | R>M | No | EVA | |
| rs3389125924 | 163 | D>Y | No | EVA | |
| rs3389124034 | 244 | R>L | No | EVA | |
| rs587382224 | 303 | E>K | No | EVA | |
| rs224515969 | 331 | E>* | No | EVA |
No associated diseases with Q9CQ35
6 regional properties for Q9CQ35
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Elongation factor EFG, domain V-like | 462 - 546 | IPR000640 |
| domain | Translational (tr)-type GTP-binding domain | 60 - 240 | IPR000795 |
| domain | Small GTP-binding protein domain | 64 - 229 | IPR005225 |
| domain | GTP-binding protein LepA, C-terminal | 551 - 656 | IPR013842 |
| conserved_site | Tr-type G domain, conserved site | 99 - 114 | IPR031157 |
| domain | Elongation factor 4, domain IV | 464 - 542 | IPR035654 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| binding of sperm to zona pellucida | The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKASLPWSVV | WRAQSNYVRL | RRVLKLCELW | LLLVGSGLNA | KLPLEEDVDF | INEYVGLHNE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRGTVFPPGV | NLRFMTWDVA | LSRTARAWGK | KCMYSRNTHL | DKLHESHPVF | TEIGENMWVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PVEDFTVTTA | IRSWHEERKS | YSYLNDTCVE | DQNCSHYIQL | VWDSSYKVGC | AVTSCARAGG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FTHAALFICN | YAPGGTLTRR | PYQAGQFCSR | CGPGDQCTDY | LCSNTVRDEA | TYYQFWYPPW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EKPRPVVCNP | MCIFILFLRV | ASLLLCVIVV | LIVQSRFPVI | LMETPTIISA | EEEGKTEVEI |
| 310 | 320 | 330 | |||
| VMEEGEGEGE | GGEGEGEGEE | KEEEEMLEED | EQ |