| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
A G protein-coupled receptor signaling pathway in which the signal is transmitted via the inhibition of adenylyl cyclase activity and a subsequent decrease in the intracellular concentration of cyclic AMP (cAMP). |
| adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation or inhibition of adenylyl cyclase activity and a subsequent change in the intracellular concentration of cyclic AMP (cAMP). |
| calcium ion transmembrane transport |
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. |
| calcium-mediated signaling |
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. |
| calcium-mediated signaling using extracellular calcium source |
The series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response. |
| cell projection organization |
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. |
| cellular response to ATP |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus. |
| cellular response to organic cyclic compound |
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. |
| cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration |
The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration. |
| establishment of localization in cell |
Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. |
| G protein-coupled adenosine receptor signaling pathway |
The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. |
| G protein-coupled receptor signaling pathway |
The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. |
| glial cell migration |
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. |
| ion transport |
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| lamellipodium assembly |
Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell. |
| negative regulation of cell differentiation |
Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. |
| negative regulation of norepinephrine secretion |
Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. |
| phospholipase C-activating G protein-coupled receptor signaling pathway |
A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of phospholipase C (PLC) and a subsequent increase in the intracellular concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG). |
| platelet activation |
A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. |
| platelet aggregation |
The adhesion of one platelet to one or more other platelets via adhesion molecules. |
| positive regulation of cell adhesion mediated by integrin |
Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin. |
| positive regulation of chemotaxis |
Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. |
| positive regulation of integrin activation by cell surface receptor linked signal transduction |
Any process that activates or increases the frequency, rate, or extent of integrin activation by cell surface receptor linked signal transduction. This can occur by increased affinity of an integrin for its extracellular ligands. |
| positive regulation of ion transport |
Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| positive regulation of microglial cell migration |
Any process that activates or increases the frequency, rate or extent of microglial cell migration. |
| positive regulation of protein kinase B signaling |
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. |
| positive regulation of ruffle assembly |
Any process that activates or increases the frequency, rate or extent of ruffle assembly. |
| potassium ion transmembrane transport |
A process in which a potassium ion is transported from one side of a membrane to the other. |
| protein kinase B signaling |
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound. |
| regulation of calcium ion transport |
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of chemotaxis |
Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. |
| regulation of microglial cell migration |
Any process that modulates the frequency, rate or extent of microglial cell migration. |
| response to axon injury |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus. |
| substrate-dependent cell migration, cell extension |
The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell. |
| visual system development |
The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. |