Q96A65
PR
Gene name |
EXOC4 (KIAA1699, SEC8, SEC8L1) |
Protein name |
Exocyst complex component 4 |
Names |
Exocyst complex component Sec8 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:60412 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q96A65
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7PC5 | X-ray | 170 A | B | 965-974 | PDB |
| AF-Q96A65-F1 | Predicted | AlphaFoldDB |
758 variants for Q96A65
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
CA186070 RCV000162153 rs730882233 |
578 | Q>R | Meckel-Gruber syndrome [ClinVar] | Yes |
ClinGen ClinVar Ensembl dbSNP |
|
rs747454663 CA4491080 |
2 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA4491082 rs771535728 |
3 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491081 rs771535728 |
3 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491083 rs745993393 |
4 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs145271795 CA4491084 |
5 | A>G | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 5 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs145271795 CA4491085 |
5 | A>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4491087 rs540463431 |
6 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1367813440 CA369465174 |
7 | G>D | No |
ClinGen TOPMed |
|
|
rs773118344 CA4491088 |
8 | G>V | No |
ClinGen ExAC gnomAD |
|
|
rs1320362788 CA369465179 |
8 | G>W | No |
ClinGen gnomAD |
|
|
rs766383620 CA4491090 |
10 | Y>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491089 rs760528562 |
10 | Y>H | No |
ClinGen ExAC |
|
| TCGA novel | 11 | R>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 11 | R>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1562988841 CA369465199 |
11 | R>T | No |
ClinGen Ensembl |
|
|
CA4491091 rs753326786 |
12 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs759071721 CA4491092 |
12 | S>I | No |
ClinGen ExAC gnomAD |
|
|
CA369465206 rs759071721 |
12 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA4491093 rs764801416 |
13 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs758899475 CA167399924 |
14 | V>A | No |
ClinGen Ensembl |
|
|
rs758125085 CA4491095 |
15 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA4491096 rs147231122 |
15 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491097 rs560096370 |
19 | D>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA369465259 rs1369589238 |
20 | P>H | No |
ClinGen gnomAD |
|
|
CA369465260 rs1369589238 |
20 | P>L | No |
ClinGen gnomAD |
|
|
CA369465261 rs1369589238 |
20 | P>R | No |
ClinGen gnomAD |
|
|
COSM3778122 CA369465265 COSM3778121 rs183280115 |
21 | S>* | Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes NCI-TCGA gnomAD |
|
COSM3831913 CA167399925 COSM452375 rs183280115 |
21 | S>L | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes NCI-TCGA gnomAD |
| rs1430141106 | 21 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1449389802 CA369465288 |
25 | I>T | No |
ClinGen gnomAD |
|
|
rs1270756431 CA369465286 |
25 | I>V | No |
ClinGen TOPMed |
|
| TCGA novel | 29 | R>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369466332 rs1192538966 |
29 | R>S | No |
ClinGen TOPMed |
|
|
CA369466335 rs1562997773 |
30 | T>A | No |
ClinGen Ensembl |
|
|
CA4491125 rs749428746 |
32 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA4491126 rs755136661 |
36 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA167402222 COSM1448158 rs978166030 |
36 | D>N | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs115798810 CA4491128 |
38 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA369466398 TCGA novel rs1246966392 |
39 | D>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen gnomAD |
|
CA369466411 rs1276911262 |
41 | E>V | No |
ClinGen TOPMed |
|
|
rs770723380 CA4491129 |
42 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491130 rs371782269 |
43 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 43 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491132 rs148842600 |
45 | G>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491133 rs774958278 |
45 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs148842600 CA4491131 |
45 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs762544615 CA4491134 |
46 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491135 rs763612418 |
46 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369466442 rs763612418 |
46 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs376782759 CA4491136 |
49 | E>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA369466482 rs1435773420 |
52 | E>G | No |
ClinGen gnomAD |
|
|
CA167402223 rs939586317 |
54 | C>Y | No |
ClinGen Ensembl |
|
|
COSM1699381 rs200320447 CA4491138 |
56 | R>C | skin [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
CA4491139 rs750885840 |
56 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA4491140 rs750885840 |
56 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs767045490 CA4491141 |
57 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA167402224 rs1038063999 |
59 | D>G | No |
ClinGen TOPMed |
|
|
rs1265402991 CA369466550 |
62 | I>T | No |
ClinGen TOPMed |
|
|
rs753814143 CA369466581 |
66 | Y>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM204210 CA369466609 rs1290075190 |
70 | T>M | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
rs1196389683 CA369466624 |
73 | I>V | No |
ClinGen gnomAD |
|
|
CA4491145 rs201300506 |
74 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA4491146 COSM3431254 COSM204211 rs775034999 |
74 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs1411920706 CA369466636 |
75 | T>I | No |
ClinGen gnomAD |
|
|
CA4491147 rs780930711 COSM1548156 |
77 | Q>R | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA369466657 rs1183477326 |
78 | S>N | No |
ClinGen gnomAD |
|
|
rs1391634899 CA369466670 |
80 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1391634899 CA369466669 |
80 | T>P | No |
ClinGen TOPMed gnomAD |
|
|
CA369466685 rs1356331651 |
82 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs769669510 CA4491149 |
82 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed |
|
rs769669510 CA167402227 |
82 | R>L | No |
ClinGen ExAC TOPMed |
|
|
rs780070557 CA4491150 |
83 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA369466695 rs1348571281 |
84 | T>A | No |
ClinGen gnomAD |
|
|
rs1284568143 CA369466700 |
85 | N>D | No |
ClinGen gnomAD |
|
|
rs1355455263 CA369466703 |
85 | N>S | No |
ClinGen gnomAD |
|
| TCGA novel | 86 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1300875092 CA369466712 |
86 | S>F | No |
ClinGen TOPMed |
|
|
CA167402228 rs1045453395 |
87 | R>* | No |
ClinGen TOPMed |
|
|
rs199786320 COSM3431255 COSM1448159 CA4491152 |
87 | R>Q | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs762599364 CA167402230 |
89 | K>Q | No |
ClinGen Ensembl |
|
|
CA369466776 rs138076847 |
94 | K>R | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA167403761 rs138076847 |
94 | K>T | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
CA4491175 rs530657357 |
95 | E>D | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs112101643 CA167403762 |
96 | N>D | No |
ClinGen Ensembl |
|
|
CA369466790 rs1295013700 |
96 | N>S | No |
ClinGen gnomAD |
|
|
CA369466801 rs1349383128 |
98 | L>F | No |
ClinGen gnomAD |
|
|
rs776925272 CA4491177 |
102 | M>K | No |
ClinGen ExAC gnomAD |
|
|
rs1257051935 CA369466829 |
102 | M>L | No |
ClinGen gnomAD |
|
|
rs1257051935 CA369466828 |
102 | M>V | No |
ClinGen gnomAD |
|
|
CA369466843 rs1384567362 |
104 | L>P | No |
ClinGen TOPMed |
|
|
rs1250273700 CA369466870 |
108 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs550387931 CA4491178 |
108 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA369466890 rs1173326115 |
111 | L>V | No |
ClinGen TOPMed |
|
|
rs1188129086 CA369466897 |
112 | R>Q | No |
ClinGen gnomAD |
|
| TCGA novel | 117 | E>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1199685990 CA369466940 |
118 | G>E | No |
ClinGen gnomAD |
|
|
rs570665431 CA4491182 |
123 | H>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4491183 rs529493969 |
126 | N>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1433307410 CA369466997 |
126 | N>S | No |
ClinGen TOPMed |
|
|
CA369467009 rs1389076465 |
128 | L>S | No |
ClinGen gnomAD |
|
|
CA4491184 rs757535030 |
131 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA369467048 rs1260406362 |
133 | N>K | No |
ClinGen TOPMed |
|
|
CA4491185 rs779896876 |
133 | N>T | No |
ClinGen ExAC gnomAD |
|
|
rs753618140 CA4491186 |
134 | I>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs778741092 CA4491188 |
135 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs142569886 CA167403765 |
136 | Q>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs1209817889 CA369467081 |
138 | P>R | No |
ClinGen TOPMed |
|
|
CA167403766 rs531461738 |
140 | K>R | No |
ClinGen gnomAD |
|
|
CA369467113 rs1308759252 |
143 | Q>R | No |
ClinGen gnomAD |
|
|
rs747623725 CA4491189 |
145 | M>L | No |
ClinGen ExAC gnomAD |
|
|
CA167403767 rs919867909 |
146 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA369467138 rs1266404187 |
146 | A>V | No |
ClinGen gnomAD |
|
|
CA369467164 rs1489588861 |
150 | Y>H | No |
ClinGen gnomAD |
|
|
CA4491190 rs200463309 |
151 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM3394534 rs1370181143 COSM2770979 CA369467179 |
152 | S>N | pancreas [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs777512800 CA4491191 |
153 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1431563477 CA369467193 |
154 | T>S | No |
ClinGen gnomAD |
|
|
CA4491193 CA167403768 rs370550009 |
156 | M>I | No |
ClinGen ESP ExAC TOPMed |
|
|
CA4491194 rs777028806 |
157 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1429915048 CA369464543 |
159 | S>A | No |
ClinGen TOPMed |
|
|
rs746175040 CA4491217 |
159 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs146409877 CA4491219 |
161 | V>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491218 rs146409877 |
161 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs769191878 CA4491221 |
165 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs774394381 CA4491222 |
165 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369464585 rs1563010873 |
166 | G>D | No |
ClinGen Ensembl |
|
|
CA4491223 rs761822033 |
166 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA369464591 rs767742634 |
167 | P>H | No |
ClinGen ExAC gnomAD |
|
|
CA4491224 rs767742634 |
167 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA369464590 rs1259568154 |
167 | P>S | No |
ClinGen TOPMed |
|
|
rs1211424401 CA369464602 |
169 | L>P | No |
ClinGen TOPMed |
|
|
rs1050179425 CA369464653 |
176 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA4491226 rs759321937 |
177 | L>P | No |
ClinGen ExAC gnomAD |
|
|
COSM109686 CA167405436 rs140852002 |
178 | R>* | skin [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs140852002 CA4491227 |
178 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491228 rs145158959 |
178 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1181078687 CA369464668 |
180 | E>Q | No |
ClinGen gnomAD |
|
|
CA4491229 rs758384160 |
181 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1168904055 CA369464682 |
182 | H>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 186 | M>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs879601450 CA167405437 CA369464719 |
186 | M>I | No |
ClinGen TOPMed |
|
|
CA369464716 rs1427310862 |
186 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
CA167405438 rs756723989 |
189 | H>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369464747 rs780839998 |
190 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369464749 rs1449139186 |
191 | V>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1302640619 CA369464764 |
193 | I>T | No |
ClinGen gnomAD |
|
|
rs780366423 CA4491236 |
198 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA4491235 rs755862799 |
198 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA167405440 rs961201906 |
199 | H>Y | No |
ClinGen TOPMed |
|
|
rs1312703679 CA369464807 |
200 | L>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1322693463 CA369464830 |
203 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA4491238 rs769104059 |
204 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1466128962 CA369464843 |
205 | T>S | No |
ClinGen gnomAD |
|
|
rs748194544 CA4491240 |
207 | R>* | No |
ClinGen ExAC gnomAD |
|
|
COSM1085715 rs772062658 CA4491241 |
207 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1192442999 CA369464861 |
208 | V>A | No |
ClinGen gnomAD |
|
|
CA4491242 rs773403062 |
209 | V>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1427790546 CA369464863 |
209 | V>L | No |
ClinGen gnomAD |
|
|
CA4491244 rs771323780 |
211 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491246 rs140653799 |
211 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA167405442 rs140653799 |
211 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs771323780 CA4491245 |
211 | R>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764055707 CA4491247 |
212 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491248 rs751464157 |
213 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA4491249 rs761868306 |
214 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA4491251 rs749991089 |
215 | K>Q | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 215 | K>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| VAR_036292 | 220 | S>F | a colorectal cancer sample; somatic mutation [UniProt] | No | UniProt |
|
CA369465423 COSM1448160 rs1229655082 |
220 | S>P | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs538087610 CA4491271 |
221 | L>V | No |
ClinGen ExAC gnomAD |
|
|
rs753150357 CA4491274 |
222 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369465540 rs1267302005 |
224 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA369465532 rs1584805304 |
224 | D>G | No |
ClinGen Ensembl |
|
| TCGA novel | 224 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491275 rs758778712 |
228 | P>A | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 230 | I>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369465679 rs1363557706 |
232 | V>A | No |
ClinGen gnomAD |
|
|
rs975024434 CA167406539 |
232 | V>I | No |
ClinGen Ensembl |
|
|
rs1468965534 CA369465687 |
233 | T>I | No |
ClinGen gnomAD |
|
|
rs974892070 CA369465691 |
234 | N>D | No |
ClinGen TOPMed |
|
|
rs1165183818 CA369465695 |
234 | N>S | No |
ClinGen gnomAD |
|
|
CA167406540 rs974892070 |
234 | N>Y | No |
ClinGen TOPMed |
|
|
rs757424698 CA4491278 |
236 | P>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747016421 CA4491277 |
236 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs781478736 CA4491279 |
239 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA4491280 rs544415669 |
239 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
CA369465768 rs1307396174 |
241 | F>L | No |
ClinGen gnomAD |
|
|
rs770179415 CA4491281 |
242 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs372024692 CA4491283 |
243 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA gnomAD |
|
CA369465797 rs1584805403 |
244 | T>P | No |
ClinGen Ensembl |
|
|
CA4491284 rs771866368 |
245 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA4491285 rs771866368 |
245 | S>Y | No |
ClinGen ExAC gnomAD |
|
|
rs1243398512 CA369465828 |
246 | H>R | No |
ClinGen gnomAD |
|
|
rs760122404 CA4491286 |
247 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491287 rs765864133 |
248 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs1431700270 CA369465845 |
248 | S>P | No |
ClinGen TOPMed |
|
|
CA4491288 rs776194165 |
249 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491289 rs138281330 |
250 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4491290 rs138281330 |
250 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA167406542 rs942133809 |
251 | G>E | No |
ClinGen Ensembl |
|
|
rs375355028 CA4491292 |
253 | S>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491293 rs764447536 |
254 | S>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 256 | R>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs775220009 CA369467233 |
256 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775220009 CA4491308 |
256 | R>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369467246 rs1472150577 |
258 | I>V | No |
ClinGen TOPMed |
|
|
rs762569848 CA4491309 |
259 | N>I | No |
ClinGen ExAC gnomAD |
|
|
rs1270890013 CA369467273 |
262 | D>H | No |
ClinGen gnomAD |
|
|
CA369467281 rs1371474931 |
263 | I>V | No |
ClinGen gnomAD |
|
|
CA369467296 rs1467507501 |
265 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
CA167411039 rs953735832 |
266 | D>E | No |
ClinGen Ensembl |
|
|
rs149578002 CA167411038 |
266 | D>N | No |
ClinGen ESP |
|
| TCGA novel | 268 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs752011481 CA4491311 |
270 | D>V | No |
ClinGen ExAC gnomAD |
|
|
rs1405040713 CA369467333 |
270 | D>Y | No |
ClinGen gnomAD |
|
|
rs1322083570 CA369467341 |
271 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA369467362 rs1381101309 |
274 | N>D | No |
ClinGen gnomAD |
|
|
rs1292823382 CA369467369 |
275 | S>G | No |
ClinGen gnomAD |
|
|
rs768161600 CA4491313 |
275 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs1439357436 CA369467379 |
276 | T>S | No |
ClinGen TOPMed |
|
|
rs750491430 CA4491314 |
280 | G>S | No |
ClinGen ExAC gnomAD |
|
|
CA4491315 rs143291638 |
281 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1323228952 CA369467428 |
284 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
CA4491316 rs139031553 |
285 | G>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs754080176 CA4491317 |
285 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA4491320 rs545267730 |
287 | A>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA167411040 rs944286544 |
289 | L>R | No |
ClinGen Ensembl |
|
|
rs931505556 CA167411041 |
295 | T>A | No |
ClinGen TOPMed gnomAD |
|
|
CA4491324 rs769331521 |
297 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs762634261 CA4491326 |
299 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA4491325 rs147214615 |
299 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491327 rs140636237 |
300 | I>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491328 rs774808256 |
302 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs762300660 COSM1187440 CA4491329 |
302 | R>H | lung [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs762300660 CA369467545 |
302 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369467552 rs1365946196 |
303 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
CA369467584 rs1222295239 |
307 | L>F | No |
ClinGen gnomAD |
|
|
rs868537272 CA167411042 |
309 | Q>P | No |
ClinGen Ensembl |
|
|
CA369467626 rs750982913 |
313 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA167411043 rs141369405 |
315 | T>A | No |
ClinGen ESP |
|
|
rs1563033068 CA369467638 |
315 | T>I | No |
ClinGen Ensembl |
|
| TCGA novel | 315 | T>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs374961055 CA167411044 |
316 | T>I | No |
ClinGen ESP gnomAD |
|
|
CA4491334 rs766479473 |
316 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs374961055 CA369467642 |
316 | T>S | No |
ClinGen ESP gnomAD |
|
|
CA369467649 rs1268014055 |
317 | Q>H | No |
ClinGen gnomAD |
|
|
rs1471014261 CA369467646 |
317 | Q>P | No |
ClinGen TOPMed |
|
|
rs200156091 CA4491337 |
319 | A>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA369467657 rs753908169 |
319 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA4491335 rs753908169 |
319 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA4491336 rs200156091 |
319 | A>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA369467669 rs1233209502 |
321 | S>R | No |
ClinGen TOPMed |
|
|
CA4491338 rs751285429 |
321 | S>T | No |
ClinGen ExAC gnomAD |
|
|
CA369467698 rs201609585 |
325 | R>G | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
rs369312406 CA4491340 |
325 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369312406 CA4491342 |
325 | R>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs369312406 CA4491341 |
325 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA4491339 rs201609585 |
325 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed |
|
|
CA369467701 rs1584847526 |
326 | G>A | No |
ClinGen Ensembl |
|
|
rs768384421 CA4491346 |
326 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768384421 CA4491345 |
326 | G>W | No |
ClinGen ExAC TOPMed gnomAD |
|
| rs1563033105 | 327 | E>G | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA167411045 rs77094376 |
327 | E>G | No |
ClinGen Ensembl |
|
|
CA4491348 rs772554686 |
329 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369467729 rs1403613432 |
331 | V>M | No |
ClinGen gnomAD |
|
|
rs370517844 CA4491349 |
332 | E>D | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs761216417 CA4491350 |
333 | N>K | No |
ClinGen ExAC gnomAD |
|
|
rs1391197446 CA369467752 |
334 | Q>P | No |
ClinGen TOPMed gnomAD |
|
|
CA4491351 rs766848115 |
335 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA369465414 rs1273561595 |
336 | R>S | No |
ClinGen gnomAD |
|
|
CA369465619 rs1465990320 |
346 | F>I | No |
ClinGen TOPMed |
|
|
CA369465623 rs1257517214 |
346 | F>S | No |
ClinGen gnomAD |
|
| TCGA novel | 347 | D>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1052262669 CA167413093 |
349 | F>C | No |
ClinGen gnomAD |
|
|
rs1208860447 CA369465706 |
351 | A>V | No |
ClinGen TOPMed |
|
|
CA4491369 rs149904766 |
352 | V>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA4491368 rs149904766 |
352 | V>L | No |
ClinGen ESP ExAC gnomAD |
|
|
CA369465742 rs146469408 |
354 | A>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491370 rs146469408 |
354 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA369465750 rs1341111881 |
354 | A>V | No |
ClinGen TOPMed |
|
|
rs777013493 CA4491372 |
356 | H>R | No |
ClinGen ExAC gnomAD |
|
|
rs577020229 CA4491371 |
356 | H>Y | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs765294870 CA4491374 |
357 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs546077707 CA167413095 |
360 | L>M | No |
ClinGen 1000Genomes gnomAD |
|
| TCGA novel | 362 | Y>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1437627414 CA369465862 |
364 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
CA369465873 rs1361418951 |
365 | D>G | No |
ClinGen gnomAD |
|
| TCGA novel | 365 | D>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491377 rs764321303 |
365 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs750166788 CA4491378 |
366 | T>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750166788 CA369465882 |
366 | T>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369465886 rs1563041213 |
366 | T>S | No |
ClinGen Ensembl |
|
|
rs1202809620 CA369465892 TCGA novel |
367 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
NCI-TCGA ClinGen gnomAD |
|
rs1445976599 CA369465917 |
370 | P>A | No |
ClinGen TOPMed |
|
|
rs1010602343 CA167413096 |
370 | P>L | No |
ClinGen Ensembl |
|
|
CA4491380 rs766289665 |
371 | L>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs143199058 CA4491382 |
374 | Q>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs778560013 CA4491383 |
375 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA369465989 rs1170941256 |
377 | I>M | No |
ClinGen TOPMed |
|
|
rs747715190 CA4491384 |
377 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs920754917 CA167413097 |
377 | I>V | No |
ClinGen TOPMed |
|
|
CA369465994 rs1390451703 |
378 | K>R | No |
ClinGen TOPMed |
|
|
rs1047959899 CA167413098 |
380 | Y>C | No |
ClinGen TOPMed |
|
|
CA369466011 rs1176169557 |
381 | D>H | No |
ClinGen gnomAD |
|
|
rs1482943898 CA369466029 |
383 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs747354706 CA4491387 |
384 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1458996375 CA369466035 |
384 | D>Y | No |
ClinGen gnomAD |
|
|
rs1344644570 CA369466040 |
385 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
CA4491388 rs527959228 |
388 | K>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369466071 rs1222897112 |
389 | I>N | No |
ClinGen gnomAD |
|
|
CA4491389 rs369040208 |
389 | I>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1281129851 CA369466078 |
390 | Q>R | No |
ClinGen gnomAD |
|
|
CA369467781 rs1267407517 |
395 | M>L | No |
ClinGen TOPMed gnomAD |
|
|
rs752184265 CA4491406 |
397 | L>I | No |
ClinGen ExAC gnomAD |
|
|
CA4491407 rs758007989 |
398 | T>I | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 399 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs777395455 CA4491408 |
403 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs1412028547 CA369467840 |
403 | M>T | No |
ClinGen TOPMed |
|
|
CA4491410 rs757004114 |
405 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs751143671 CA4491409 |
405 | N>Y | No |
ClinGen ExAC gnomAD |
|
|
CA369467862 rs1424137158 |
406 | T>I | No |
ClinGen gnomAD |
|
|
CA4491411 rs781398971 |
407 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491412 rs200535304 |
407 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1563079684 CA369467872 |
408 | T>M | No |
ClinGen Ensembl |
|
|
rs1333813020 CA369467876 |
409 | A>D | No |
ClinGen TOPMed gnomAD |
|
|
rs768596052 CA4491416 |
418 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768596052 CA4491417 |
418 | Y>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369467941 rs1342076453 |
419 | A>D | No |
ClinGen gnomAD |
|
|
CA4491420 rs772392618 |
421 | T>A | No |
ClinGen ExAC gnomAD |
|
|
COSM3698180 CA167424007 COSM3698181 rs989563113 |
423 | R>* | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
rs776508325 CA4491421 |
423 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs763511126 CA369467989 |
427 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763511126 CA4491427 |
427 | A>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491424 rs752662890 |
427 | A>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752662890 CA4491425 |
427 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763511126 CA4491426 |
427 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1394012263 CA369467991 |
428 | F>L | No |
ClinGen gnomAD |
|
|
CA4491429 rs756804611 |
429 | F>L | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 430 | A>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 433 | K>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 433 | K>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491430 rs780903574 |
434 | P>T | No |
ClinGen ExAC gnomAD |
|
|
CA4491431 rs541978257 |
436 | R>K | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA369468059 rs1378416459 COSM1548154 |
437 | P>L | lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA369468061 rs1299159007 |
438 | K>E | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA4491434 rs780446105 |
439 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 439 | N>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491435 rs143823778 |
439 | N>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491433 rs780446105 |
439 | N>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1270162361 CA369468077 |
440 | S>C | No |
ClinGen gnomAD |
|
|
rs746122885 CA167424008 |
441 | L>H | No |
ClinGen Ensembl |
|
|
rs1225749696 CA369468088 |
442 | F>C | No |
ClinGen gnomAD |
|
|
rs373714478 CA167424009 |
442 | F>L | No |
ClinGen ESP TOPMed |
|
|
CA4491453 rs755379810 |
443 | K>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491436 rs778843137 |
443 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1032578634 CA369468118 |
445 | E>* | No |
ClinGen TOPMed |
|
|
COSM3431257 COSM1673551 rs1032578634 CA167424513 |
445 | E>K | large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
COSM1548153 CA4491454 rs545066605 |
446 | S>L | lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs1021541827 CA167424514 |
447 | S>F | No |
ClinGen TOPMed |
|
|
CA4491456 COSM136632 rs531366432 |
448 | S>F | skin [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA4491457 rs199516005 |
449 | H>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA369468142 rs199516005 |
449 | H>P | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA369468152 rs1332345362 |
451 | I>L | No |
ClinGen TOPMed |
|
|
CA4491459 rs771340209 |
455 | A>T | No |
ClinGen ExAC gnomAD |
|
|
rs775370795 CA4491460 |
458 | R>* | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 459 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369468245 rs1407276527 |
464 | L>F | No |
ClinGen gnomAD |
|
|
CA4491462 rs749115364 |
465 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1204619737 CA369468250 |
465 | Y>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
COSM1085717 rs761705485 CA4491465 |
467 | R>Q | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs774368637 CA4491464 |
467 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491466 rs766983321 |
469 | G>R | No |
ClinGen ExAC gnomAD |
|
|
CA4491542 rs781025763 |
473 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491544 rs745335511 |
474 | G>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491543 rs745335511 |
474 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369468359 rs1196344563 |
477 | D>N | No |
ClinGen TOPMed |
|
|
rs751273688 CA4491545 |
478 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1316865963 CA369468382 |
480 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs1360897074 CA369468392 |
481 | E>G | No |
ClinGen gnomAD |
|
|
rs774798213 CA4491548 |
487 | F>V | No |
ClinGen ExAC gnomAD |
|
|
CA4491549 rs748463481 |
488 | V>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748463481 CA4491550 |
488 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369468447 rs1307881359 |
490 | K>Q | No |
ClinGen TOPMed |
|
|
CA167441122 rs141069340 |
490 | K>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491551 rs141069340 |
490 | K>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1420811144 CA369468467 |
493 | A>S | No |
ClinGen gnomAD |
|
|
rs761291706 CA4491552 |
494 | R>I | No |
ClinGen ExAC gnomAD |
|
|
CA369468486 rs1338841816 |
496 | I>V | No |
ClinGen TOPMed gnomAD |
|
|
rs375703536 CA4491553 |
497 | T>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA369468500 rs1231395466 |
498 | V>A | No |
ClinGen gnomAD |
|
|
CA4491555 rs759701016 |
498 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs556266260 CA167441124 |
505 | R>G | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1329760303 CA369469980 |
510 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
CA369469997 rs1446936793 |
511 | E>* | No |
ClinGen gnomAD |
|
|
rs1440100319 CA369470027 |
512 | H>D | No |
ClinGen TOPMed |
|
|
CA167461801 rs757501836 |
513 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA369470108 rs1368205552 |
517 | G>D | No |
ClinGen gnomAD |
|
|
CA4491569 rs778238555 |
518 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs747463580 CA4491570 |
522 | C>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771444968 CA4491571 |
523 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771444968 CA167461803 |
523 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369470212 rs1446395002 |
525 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs1446395002 CA369470205 |
525 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA4491573 rs776629991 |
525 | R>P | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA4491572 rs776629991 |
525 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA167461804 rs146531749 |
527 | F>L | No |
ClinGen ESP TOPMed gnomAD |
|
| TCGA novel | 527 | F>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369470242 rs1563011300 |
528 | L>F | No |
ClinGen Ensembl |
|
| TCGA novel | 528 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491574 rs767674208 |
530 | V>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA167461806 rs948851717 |
531 | Y>C | No |
ClinGen gnomAD |
|
|
rs775554325 CA4491575 |
531 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs202018736 CA4491576 |
532 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1244398370 CA369470347 |
536 | F>S | No |
ClinGen gnomAD |
|
|
rs1237520022 CA369470359 |
538 | N>H | No |
ClinGen TOPMed |
|
|
CA369470364 rs1461392422 |
538 | N>S | No |
ClinGen gnomAD |
|
|
CA369470413 rs1182889339 |
542 | A>T | No |
ClinGen gnomAD |
|
|
rs750291765 CA4491578 |
544 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA167461808 rs980298869 |
545 | N>D | No |
ClinGen Ensembl |
|
|
CA4491579 rs760471069 |
546 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs1168840799 CA369470513 |
549 | E>G | No |
ClinGen gnomAD |
|
|
RCV000893737 CA4491581 rs149782824 |
550 | G>R | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
CA167461809 rs1008390359 |
553 | K>R | No |
ClinGen TOPMed |
|
|
CA4491582 rs754557338 |
554 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA369470610 rs1383914636 |
555 | S>C | No |
ClinGen gnomAD |
|
|
CA4491584 rs752256479 |
555 | S>P | No |
ClinGen ExAC gnomAD |
|
|
rs1216355184 CA369470648 |
557 | P>L | No |
ClinGen gnomAD |
|
|
CA4491587 rs747407987 |
560 | I>L | No |
ClinGen ExAC gnomAD |
|
|
rs575482547 CA4491588 |
560 | I>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1329108673 CA369470715 |
561 | L>P | No |
ClinGen TOPMed |
|
|
CA369470720 rs1253797333 |
562 | A>T | No |
ClinGen gnomAD |
|
|
rs1052756068 CA369470749 |
563 | N>K | No |
ClinGen TOPMed gnomAD |
|
|
CA4491590 rs746426929 |
564 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369470772 rs1184773306 |
565 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
CA4491593 rs763075145 |
567 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs768937158 CA4491594 CA369470809 |
569 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768937158 CA369470808 |
569 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369470816 rs1201734831 |
570 | L>P | No |
ClinGen TOPMed |
|
|
rs1413091962 CA369470829 |
572 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
rs766370518 CA4491597 |
573 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
rs201785279 CA167461811 COSM3942035 |
574 | R>W | oesophagus [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
rs1298752323 CA369470846 |
575 | P>L | No |
ClinGen gnomAD |
|
|
CA4491599 rs759583150 |
576 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1285028486 CA369470859 |
578 | Q>* | No |
ClinGen gnomAD |
|
|
rs762548692 CA4491619 |
579 | S>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM74560 rs763566158 CA4491620 |
579 | S>N | ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs371277479 CA4491622 |
580 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491624 rs767854929 |
581 | I>L | No |
ClinGen ExAC gnomAD |
|
|
CA4491623 rs767854929 |
581 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA4491626 rs780641719 |
582 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs750294784 CA4491625 |
582 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491627 rs749276747 |
583 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs749276747 CA369468582 |
583 | V>E | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 584 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369468594 rs1414189714 |
585 | K>E | No |
ClinGen gnomAD |
|
|
rs755063719 CA4491628 |
585 | K>R | No |
ClinGen ExAC gnomAD |
|
|
rs376345518 CA4491630 |
587 | V>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491631 rs772477021 |
588 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA369468613 rs142976261 |
588 | Q>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491632 rs142976261 |
588 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA369468623 rs1585230194 |
589 | D>E | No |
ClinGen Ensembl |
|
|
rs769571711 CA369468625 |
590 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769571711 CA4491635 |
590 | L>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369468657 rs775480288 |
595 | H>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491637 rs551191630 |
595 | H>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4491636 rs775480288 |
595 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA167470276 rs569679408 |
597 | L>F | No |
ClinGen 1000Genomes |
|
|
COSM32876 CA4491638 VAR_036293 rs768209201 |
599 | A>T | large_intestine a colorectal cancer sample; somatic mutation [Cosmic, UniProt] | No |
ClinGen cosmic curated UniProt ExAC TOPMed dbSNP gnomAD |
|
rs773908666 CA4491639 |
603 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA4491640 rs761399155 |
603 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1167187145 CA369468721 |
604 | F>S | No |
ClinGen TOPMed |
|
|
CA167470278 rs970149083 |
605 | L>R | No |
ClinGen TOPMed |
|
|
CA4491642 rs149312476 |
605 | L>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1472466211 CA369468742 |
607 | M>T | No |
ClinGen TOPMed gnomAD |
|
|
CA369468738 rs1237992093 |
607 | M>V | No |
ClinGen gnomAD |
|
|
CA167470279 rs367665594 |
608 | V>M | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs761122078 CA4491643 |
609 | C>F | No |
ClinGen ExAC gnomAD |
|
|
CA4491644 rs761122078 |
609 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
rs981947418 CA167470280 |
610 | V>A | No |
ClinGen Ensembl |
|
|
rs201852656 CA4491646 |
610 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491649 rs140299875 |
612 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4491648 rs140299875 |
612 | L>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs935262676 CA167470282 CA369468786 |
614 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
CA369468784 rs1447997230 |
614 | E>G | No |
ClinGen gnomAD |
|
| TCGA novel | 614 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA167470281 rs959853913 |
614 | E>Q | No |
ClinGen TOPMed |
|
|
CA4491651 rs747286445 |
615 | Y>* | No |
ClinGen ExAC gnomAD |
|
|
CA369468798 rs1219436643 |
616 | K>R | No |
ClinGen gnomAD |
|
|
rs1257671011 CA369468805 |
617 | D>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1257671011 CA369468806 |
617 | D>V | No |
ClinGen TOPMed gnomAD |
|
|
CA369468811 rs1381104796 |
618 | T>A | No |
ClinGen TOPMed |
|
|
CA369468815 rs1252120860 |
618 | T>I | No |
ClinGen gnomAD |
|
|
rs769605200 CA4491652 |
619 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs779783183 CA4491653 |
620 | T>I | No |
ClinGen ExAC gnomAD |
|
|
CA4491655 rs145963456 |
621 | A>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs141753800 CA4491654 |
621 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs145963456 CA4491656 |
621 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA369468840 rs1306317551 |
623 | Y>S | No |
ClinGen TOPMed |
|
|
rs1432162226 CA369468846 |
624 | R>G | No |
ClinGen TOPMed |
|
|
rs1372550504 CA369468873 |
625 | G>D | No |
ClinGen TOPMed |
|
|
rs758777671 CA4491684 |
626 | I>V | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs751604065 CA4491687 |
628 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA369468891 rs764260310 |
628 | Q>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1205813 CA4491686 rs764260310 |
628 | Q>R | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1410771814 CA369468910 |
631 | E>K | No |
ClinGen TOPMed |
|
|
CA369468921 rs1449571671 |
632 | K>I | No |
ClinGen gnomAD |
|
|
CA369468935 rs1194432362 |
634 | V>G | No |
ClinGen gnomAD |
|
| TCGA novel | 634 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369468942 rs1158595483 |
635 | I>M | No |
ClinGen TOPMed gnomAD |
|
|
CA4491690 rs753621495 |
636 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs754744267 CA4491691 |
636 | S>T | No |
ClinGen ExAC gnomAD |
|
|
rs778718228 CA4491692 |
637 | A>E | No |
ClinGen ExAC gnomAD |
|
|
CA369468953 rs778718228 |
637 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA167472831 rs929005895 |
640 | A>P | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 640 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA167472832 rs376931909 |
644 | D>G | No |
ClinGen ESP TOPMed |
|
|
CA167472833 rs757318737 |
646 | S>N | No |
ClinGen Ensembl |
|
|
rs1323229313 CA369469071 |
654 | N>K | No |
ClinGen gnomAD |
|
|
CA369469088 rs1348657231 |
656 | M>I | No |
ClinGen TOPMed |
|
|
rs745576312 CA4491700 |
656 | M>L | No |
ClinGen ExAC |
|
|
rs1189342960 CA369469098 |
658 | M>V | No |
ClinGen gnomAD |
|
|
CA4491701 rs770281475 COSM1251589 |
659 | A>V | oesophagus [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
rs776059821 CA4491702 |
660 | Q>K | No |
ClinGen ExAC gnomAD |
|
|
CA369469121 rs1585247264 |
661 | P>H | No |
ClinGen Ensembl |
|
|
CA369469134 rs1200195155 |
663 | Q>K | No |
ClinGen gnomAD |
|
|
CA369469137 rs1326029523 |
663 | Q>L | No |
ClinGen TOPMed |
|
|
CA167472836 rs1030055549 |
667 | K>E | No |
ClinGen TOPMed |
|
|
CA369469169 rs1178489626 |
668 | R>I | No |
ClinGen gnomAD |
|
|
rs764703832 CA4491704 |
671 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369469199 rs1426148834 |
672 | E>G | No |
ClinGen gnomAD |
|
|
rs774450424 CA4491705 |
673 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA4491706 rs761823774 |
674 | F>C | No |
ClinGen ExAC gnomAD |
|
|
CA369469214 rs761823774 |
674 | F>S | No |
ClinGen ExAC gnomAD |
|
|
rs1460029506 CA369469218 |
675 | I>V | No |
ClinGen gnomAD |
|
|
rs1173135747 CA369469225 |
676 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA369469564 rs1401627126 |
677 | A>T | No |
ClinGen gnomAD |
|
|
CA4491722 rs774701379 |
682 | E>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1471634406 CA369469601 |
682 | E>K | No |
ClinGen TOPMed |
|
|
rs1021109820 CA167475052 |
684 | E>G | No |
ClinGen Ensembl |
|
|
rs1175366204 CA369469614 |
684 | E>Q | No |
ClinGen Ensembl |
|
|
CA167475053 rs966999471 |
687 | I>T | No |
ClinGen Ensembl |
|
|
CA4491723 rs762421551 |
692 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA369469687 rs1183738705 |
695 | I>V | No |
ClinGen TOPMed |
|
|
rs1212497934 CA369469694 |
696 | P>A | No |
ClinGen gnomAD |
|
|
rs1302704112 CA369469696 |
696 | P>H | No |
ClinGen gnomAD |
|
|
rs772040078 CA4491724 |
698 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
rs201134202 CA167475054 |
698 | Q>P | No |
ClinGen 1000Genomes |
|
|
rs146653246 CA4491727 |
702 | R>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4491728 rs924973063 |
702 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1219242884 CA369469744 |
704 | V>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1219242884 CA369469745 |
704 | V>L | No |
ClinGen TOPMed gnomAD |
|
|
CA4491730 rs752445545 |
706 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763996192 CA4491732 |
709 | A>D | No |
ClinGen ExAC gnomAD |
|
|
CA4491734 rs757280506 |
710 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1393175322 CA369469795 |
711 | A>V | No |
ClinGen gnomAD |
|
|
rs377450937 CA4491738 |
713 | M>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs139040668 CA4491737 |
713 | M>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491736 rs139040668 |
713 | M>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491735 rs780514601 |
713 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1563064120 CA369469811 |
714 | H>N | No |
ClinGen Ensembl |
|
|
CA369469812 rs1444942616 |
714 | H>P | No |
ClinGen TOPMed |
|
|
CA369469813 rs1444942616 |
714 | H>R | No |
ClinGen TOPMed |
|
|
rs10269237 CA4491740 |
717 | L>V | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs144680892 CA4491741 |
718 | E>G | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4491742 rs748588131 |
719 | W>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369469845 rs1218117410 |
719 | W>R | No |
ClinGen gnomAD |
|
|
CA4491743 rs772647161 |
722 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369469876 rs1438542554 |
723 | R>* | No |
ClinGen TOPMed |
|
|
rs367976819 CA4491745 |
723 | R>Q | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA369469889 rs1219504996 |
724 | T>I | No |
ClinGen Ensembl |
|
|
CA167475057 rs754057400 |
725 | K>E | No |
ClinGen gnomAD |
|
|
rs371673120 CA4491746 |
727 | A>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 727 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369469927 rs1248681823 |
728 | F>S | No |
ClinGen gnomAD |
|
|
CA369469939 rs1480944840 |
729 | S>C | No |
ClinGen TOPMed |
|
|
rs1488960449 CA369469942 |
730 | N>H | No |
ClinGen gnomAD |
|
|
CA4491747 rs540616255 |
730 | N>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
| TCGA novel | 731 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 734 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs763786225 CA4491749 |
735 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
rs1159214491 CA369470028 |
736 | M>V | No |
ClinGen gnomAD |
|
|
CA369469255 rs1440696312 |
738 | S>P | No |
ClinGen gnomAD |
|
| TCGA novel | 738 | S>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491773 rs767472487 |
742 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA369469281 rs1286274495 |
742 | D>H | No |
ClinGen gnomAD |
|
|
CA4491774 rs532407295 |
743 | S>G | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs370174933 CA369469304 |
745 | T>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs370174933 CA4491775 |
745 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA4491777 rs371580481 |
747 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491779 rs764973453 |
748 | D>A | No |
ClinGen ExAC gnomAD |
|
|
CA4491780 rs752955265 |
749 | L>H | No |
ClinGen ExAC |
|
|
CA4491782 rs778149618 |
750 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs1480273714 CA369469339 |
751 | P>L | No |
ClinGen Ensembl |
|
| rs1563085372 | 751 | P>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1480273714 CA369469337 |
751 | P>Q | No |
ClinGen Ensembl |
|
|
CA4491783 rs369110502 |
751 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs369110502 CA167481617 |
751 | P>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1260910778 CA369469340 |
752 | V>M | No |
ClinGen TOPMed |
|
|
rs768954387 CA4491786 |
754 | E>A | No |
ClinGen ExAC gnomAD |
|
|
CA167481618 rs983563008 |
754 | E>K | No |
ClinGen TOPMed |
|
|
rs745992432 CA4491787 |
756 | I>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs1484908444 CA369469368 |
756 | I>N | No |
ClinGen gnomAD |
|
|
rs373770857 CA4491788 |
763 | L>F | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491789 rs775762504 |
764 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA4491790 rs764781492 |
765 | K>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491792 rs764781492 |
765 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491791 rs764781492 |
765 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs760628284 CA4491793 |
766 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs775959309 CA4491795 |
767 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752361434 CA4491798 |
773 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA369469484 rs752361434 |
773 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA4491799 rs772101936 |
773 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA369469486 rs772101936 |
773 | R>L | No |
ClinGen ExAC gnomAD |
|
|
CA4491800 rs764386579 |
774 | C>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 775 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369469523 rs1257082931 |
779 | H>L | No |
ClinGen TOPMed gnomAD |
|
|
CA369469522 rs1257082931 |
779 | H>R | No |
ClinGen TOPMed gnomAD |
|
|
rs751927709 CA4491801 |
779 | H>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1020453602 CA167481619 |
782 | V>A | No |
ClinGen Ensembl |
|
|
rs963362890 CA167482413 |
784 | V>I | No |
ClinGen Ensembl |
|
|
rs751872708 CA4491819 |
785 | H>Y | No |
ClinGen ExAC gnomAD |
|
|
rs767815009 CA4491821 |
787 | F>C | No |
ClinGen ExAC gnomAD |
|
|
CA369470054 rs1176157278 |
787 | F>L | No |
ClinGen TOPMed |
|
|
CA167482414 rs988062125 CA369470062 |
787 | F>L | No |
ClinGen TOPMed |
|
|
rs1383067240 CA369470070 |
788 | H>R | No |
ClinGen gnomAD |
|
|
rs1326632134 CA369470090 |
789 | Y>* | No |
ClinGen gnomAD |
|
|
CA4491822 rs750938818 |
789 | Y>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1370366507 CA369470100 |
790 | L>R | No |
ClinGen gnomAD |
|
|
rs756639970 CA4491823 |
792 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs753864971 CA4491825 |
794 | A>E | No |
ClinGen ExAC gnomAD |
|
|
rs753864971 CA167482415 |
794 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs780122543 CA4491824 |
794 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA369470145 rs753864971 |
794 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA369470167 rs1466505954 |
796 | E>Q | No |
ClinGen TOPMed |
|
|
CA369470204 rs1249097810 |
799 | Y>* | No |
ClinGen TOPMed |
|
|
rs927270336 CA167482416 |
799 | Y>C | No |
ClinGen Ensembl |
|
|
rs755208350 CA4491826 |
799 | Y>D | No |
ClinGen ExAC gnomAD |
|
|
CA4491827 rs755208350 |
799 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
CA369470207 rs1358001127 |
800 | A>T | No |
ClinGen gnomAD |
|
|
rs1210087858 CA369470213 |
800 | A>V | No |
ClinGen gnomAD |
|
|
CA4491829 rs770817215 |
801 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1563088189 CA369470250 |
803 | A>P | No |
ClinGen Ensembl |
|
|
CA4491830 rs370327688 |
805 | V>L | No |
ClinGen ESP TOPMed |
|
|
rs1341610745 CA369470285 |
806 | E>Q | No |
ClinGen TOPMed |
|
|
rs1420273531 CA369470301 |
807 | S>T | No |
ClinGen gnomAD |
|
|
CA4491833 rs373987535 |
808 | M>L | No |
ClinGen ESP ExAC gnomAD |
|
|
rs769624916 CA4491834 |
809 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369470394 rs1165961810 CA369470392 |
811 | D>E | No |
ClinGen TOPMed gnomAD |
|
|
CA369470458 rs1333529616 |
817 | L>F | No |
ClinGen gnomAD |
|
|
CA369470459 rs1281107634 |
817 | L>H | No |
ClinGen Ensembl |
|
|
rs1390798749 CA369470482 |
818 | N>K | No |
ClinGen gnomAD |
|
|
CA369470476 rs768204269 |
818 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768204269 CA4491837 |
818 | N>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773965833 CA4491838 |
820 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1304537492 CA369470503 |
820 | D>N | No |
ClinGen gnomAD |
|
|
CA369470521 rs1292307861 |
821 | I>V | No |
ClinGen gnomAD |
|
|
COSM1085723 CA4491840 rs767913030 |
822 | S>G | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA4491842 rs147650429 |
823 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA167482418 rs1051352042 |
823 | A>V | No |
ClinGen TOPMed |
|
|
CA4491844 rs753916487 |
828 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs766823344 CA4491843 |
828 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369470603 rs1248808875 |
829 | S>G | No |
ClinGen gnomAD |
|
|
rs1425926156 CA369470607 |
829 | S>N | No |
ClinGen gnomAD |
|
|
CA369470618 rs148073739 |
830 | A>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA4491846 rs148073739 |
830 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs772078435 CA167482419 |
831 | S>T | No |
ClinGen Ensembl |
|
| TCGA novel | 837 | F>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs758604905 CA4491848 |
837 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA369470734 rs1296390618 |
840 | I>V | No |
ClinGen gnomAD |
|
|
CA369470758 rs1415153994 |
842 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA4491870 rs764247002 |
843 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA167482718 rs917262024 |
848 | I>T | No |
ClinGen TOPMed |
|
|
rs755835378 CA4491872 |
849 | S>F | No |
ClinGen ExAC gnomAD |
|
|
rs369751839 CA167482719 |
850 | C>F | No |
ClinGen ESP |
|
|
CA369470927 rs1585317466 |
851 | I>M | No |
ClinGen Ensembl |
|
|
rs961922706 CA167482720 |
852 | L>H | No |
ClinGen TOPMed gnomAD |
|
|
rs754925166 CA4491875 |
853 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs778325501 CA4491876 |
854 | N>D | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 855 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA369470961 rs1392959563 |
857 | Q>R | No |
ClinGen gnomAD |
|
|
rs747685608 CA4491877 |
859 | F>L | No |
ClinGen ExAC gnomAD |
|
|
CA369470983 rs1344211033 |
860 | R>K | No |
ClinGen gnomAD |
|
|
CA4491879 rs373447019 |
861 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA4491880 rs746714622 |
865 | S>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369471029 rs1285745918 |
867 | I>V | No |
ClinGen TOPMed |
|
|
CA369471036 rs1216830112 |
868 | K>E | No |
ClinGen TOPMed |
|
|
rs1218016949 CA369471040 |
868 | K>R | No |
ClinGen Ensembl |
|
|
CA369471066 rs1442196783 |
871 | C>* | No |
ClinGen gnomAD |
|
| TCGA novel | 871 | C>W | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1346727019 CA369471098 |
876 | V>I | No |
ClinGen TOPMed |
|
|
CA369471114 rs1303333431 |
878 | Q>R | No |
ClinGen gnomAD |
|
| TCGA novel | 882 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs200052598 CA4491881 |
883 | N>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA4491882 rs777191746 |
884 | I>N | No |
ClinGen ExAC gnomAD |
|
|
CA4491883 rs201940150 |
886 | M>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1213943997 CA369471177 |
887 | S>L | No |
ClinGen gnomAD |
|
|
CA4491885 rs140959939 |
888 | R>W | No |
ClinGen ESP ExAC gnomAD |
|
|
rs762919620 CA4491886 |
892 | L>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA369471252 rs1436078501 |
896 | R>S | No |
ClinGen gnomAD |
|
|
CA369471261 rs1212712130 |
898 | Y>H | No |
ClinGen gnomAD |
|
|
CA369471280 rs1204943640 |
900 | E>G | No |
ClinGen gnomAD |
|
|
CA4491913 rs777087179 |
900 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1185382763 CA369471286 |
901 | M>V | No |
ClinGen gnomAD |
|
|
rs751083672 CA4491916 |
904 | N>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs199617480 CA4491917 |
905 | T>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA4491918 rs745556169 |
907 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs749704827 CA4491921 |
908 | E>D | No |
ClinGen ExAC gnomAD |
|
|
rs1414327118 CA369471335 |
908 | E>G | No |
ClinGen TOPMed gnomAD |
|
|
CA4491920 rs780529434 |
908 | E>K | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 909 | L>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491923 rs774258872 |
911 | N>K | No |
ClinGen ExAC gnomAD |
|
|
CA369471361 rs1218461717 |
913 | V>M | No |
ClinGen TOPMed |
|
| TCGA novel | 914 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1337340321 CA369471367 |
914 | V>L | No |
ClinGen gnomAD |
|
|
rs1236430551 CA369471382 |
916 | Q>E | No |
ClinGen gnomAD |
|
|
CA369471387 rs1280725977 |
916 | Q>H | No |
ClinGen gnomAD |
|
|
rs1563110273 CA369471392 |
917 | G>D | No |
ClinGen Ensembl |
|
|
rs1276379574 CA369471395 |
918 | V>M | No |
ClinGen TOPMed |
|
|
rs138103779 CA4491926 |
920 | Y>S | No |
ClinGen ESP ExAC gnomAD |
|
|
COSM1448169 CA4491927 rs149542788 |
921 | T>M | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs267601298 CA167489075 |
922 | E>K | No |
ClinGen Ensembl |
|
|
CA369471437 rs1239885003 |
924 | E>G | No |
ClinGen gnomAD |
|
|
CA167489076 rs934708466 |
925 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
rs775369791 CA4491929 |
925 | Y>H | No |
ClinGen ExAC gnomAD |
|
|
rs762730898 CA4491930 |
926 | I>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1169322676 CA369471448 |
926 | I>V | No |
ClinGen gnomAD |
|
|
CA167489078 rs202008012 |
928 | A>G | No |
ClinGen gnomAD |
|
|
rs372175359 CA4491933 |
928 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA167489079 rs967160906 |
929 | L>V | No |
ClinGen Ensembl |
|
|
rs750088564 CA4491935 |
932 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs199638264 CA167489080 |
934 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA4491936 rs200509714 |
934 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA369471510 rs6953296 |
936 | Q>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA369471512 rs749697208 |
937 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA4491938 rs749697208 |
937 | T>P | No |
ClinGen ExAC gnomAD |
|
|
CA369471535 rs1281443973 |
941 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA4491941 rs748689718 |
944 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs1223871786 CA369471562 |
945 | Q>P | No |
ClinGen TOPMed |
|
|
CA369471563 rs1223871786 |
945 | Q>R | No |
ClinGen TOPMed |
|
|
CA4491943 rs111239622 |
947 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA167489084 rs922036511 |
950 | Q>P | No |
ClinGen gnomAD |
|
|
CA369471596 rs922036511 |
950 | Q>R | No |
ClinGen gnomAD |
|
|
CA4491945 rs771186541 |
951 | R>S | No |
ClinGen ExAC gnomAD |
|
|
CA369471607 rs1463066117 |
952 | L>F | No |
ClinGen gnomAD |
|
|
CA4491947 rs762787759 |
953 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs183441634 CA4491946 |
953 | K>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 954 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA4491948 rs369505087 |
955 | I>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1585365966 CA369471639 |
957 | C>G | No |
ClinGen Ensembl |
|
|
rs1336134896 CA369471664 |
960 | A>S | No |
ClinGen gnomAD |
|
|
rs761900215 CA4491950 |
968 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1233335515 CA369471729 |
969 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
CA4491953 rs755790912 |
971 | I>V | No |
ClinGen ExAC gnomAD |
|
|
rs1208609647 CA369471757 |
973 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1208609647 CA369471755 |
973 | T>N | No |
ClinGen TOPMed gnomAD |
|
|
CA369471758 rs1438763079 COSM1330063 |
974 | V>I | ovary Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
No associated diseases with Q96A65
1 regional properties for Q96A65
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exocyst complex component Sec8, N-terminal | 45 - 143 | IPR007191 |
Functions
10 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| exocyst | A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. |
| Flemming body | A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge. |
| growth cone membrane | The portion of the plasma membrane surrounding a growth cone. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| microvillus | Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. |
| myelin sheath abaxonal region | The region of the myelin sheath furthest from the axon. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| synapse | The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| PDZ domain binding | Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins. |
| protein N-terminus binding | Binding to a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue. |
| small GTPase binding | Binding to a small monomeric GTPase. |
10 GO annotations of biological process
| Name | Definition |
|---|---|
| chemical synaptic transmission | The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| Golgi to plasma membrane transport | The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. |
| membrane fission | A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes. |
| mitotic cytokinesis | A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells. |
| paraxial mesoderm formation | The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of macroautophagy | Any process that modulates the frequency, rate or extent of macroautophagy. |
| vesicle docking involved in exocytosis | The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis. |
| vesicle tethering involved in exocytosis | The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VNH6 | Sec8 | Exocyst complex component 4 | Drosophila melanogaster (Fruit fly) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAEAAGGKY | RSTVSKSKDP | SGLLISVIRT | LSTSDDVEDR | ENEKGRLEEA | YEKCDRDLDE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LIVQHYTELT | TAIRTYQSIT | ERITNSRNKI | KQVKENLLSC | KMLLHCKRDE | LRKLWIEGIE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HKHVLNLLDE | IENIKQVPQK | LEQCMASKHY | LSATDMLVSA | VESLEGPLLQ | VEGLSDLRLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LHSKKMNLHL | VLIDELHRHL | YIKSTSRVVQ | RNKEKGKISS | LVKDASVPLI | DVTNLPTPRK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FLDTSHYSTA | GSSSVREINL | QDIKEDLELD | PEENSTLFMG | ILIKGLAKLK | KIPETVKAII |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ERLEQELKQI | VKRSTTQVAD | SGYQRGENVT | VENQPRLLLE | LLELLFDKFN | AVAAAHSVVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GYLQDTVVTP | LTQQEDIKLY | DMADVWVKIQ | DVLQMLLTEY | LDMKNTRTAS | EPSAQLSYAS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TGREFAAFFA | KKKPQRPKNS | LFKFESSSHA | ISMSAYLREQ | RRELYSRSGE | LQGGPDDNLI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EGGGTKFVCK | PGARNITVIF | HPLLRFIQEI | EHALGLGPAK | QCPLREFLTV | YIKNIFLNQV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LAEINKEIEG | VTKTSDPLKI | LANADTMKVL | GVQRPLLQST | IIVEKTVQDL | LNLMHDLSAY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SDQFLNMVCV | KLQEYKDTCT | AAYRGIVQSE | EKLVISASWA | KDDDISRLLK | SLPNWMNMAQ |
| 670 | 680 | 690 | 700 | 710 | 720 |
| PKQLRPKREE | EEDFIRAAFG | KESEVLIGNL | GDKLIPPQDI | LRDVSDLKAL | ANMHESLEWL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ASRTKSAFSN | LSTSQMLSPA | QDSHTNTDLP | PVSEQIMQTL | SELAKSFQDM | ADRCLLVLHL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| EVRVHCFHYL | IPLAKEGNYA | IVANVESMDY | DPLVVKLNKD | ISAIEEAMSA | SLQQHKFQYI |
| 850 | 860 | 870 | 880 | 890 | 900 |
| FEGLGHLISC | ILINGAQYFR | RISESGIKKM | CRNIFVLQQN | LTNITMSREA | DLDFARQYYE |
| 910 | 920 | 930 | 940 | 950 | 960 |
| MLYNTADELL | NLVVDQGVKY | TELEYIHALT | LLHRSQTGVG | ELTTQNTRLQ | RLKEIICEQA |
| 970 | |||||
| AIKQATKDKK | ITTV |