Q93655
Gene name |
nac-1 (indy-1, nad-1, F31F6.6) |
Protein name |
Sodium-dependent low-affinity dicarboxylate transporter 1 |
Names |
Na(+)/dicarboxylate cotransporter 1, NaDC-1, ceNaDC1 |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_F31F6.6 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q93655
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q93655-F1 | Predicted | AlphaFoldDB |
No variants for Q93655
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q93655 | |||||
No associated diseases with Q93655
1 regional properties for Q93655
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Sodium/sulphate symporter, conserved site | 493 - 509 | IPR031312 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| citrate transmembrane transporter activity | Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other. |
| low-affinity sodium:dicarboxylate symporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. |
| succinate transmembrane transporter activity | Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| anion transmembrane transport | The process in which an anion is transported across a membrane. |
| citrate transport | The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| succinate transport | The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARKRGISSL | LLIYKQSFVI | WGALLIFSPL | LMFVGDSHGL | QAKCLYCVAV | MGSYWVFEAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PLAITAFIPM | ILFPLFGIMR | SEEVARAYLP | DTCFLFMGGL | MVALAVEKCE | LHARVALFVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KTVGSEPARV | MAGFMGVTGF | LSMWISNTAT | TALMVPILQS | VITELVSNHR | MEDLVALCEA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HHNSSRKHSV | GMRRLSLPNE | NNEIKREEMD | TAMSPREQKM | AKGLMLSVCF | SANIGGAATI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TGTASNLVLV | GQLNELFPGA | DTGVNFLSWL | IFAFPMVFCC | LIYCWCVLYL | LYLRDAPKGS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IIVTRKLQQK | YNELHAFSFA | EMAVIFCFAL | LLVLWILREP | QVVPGWGEMF | KDEFVSDATS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AMFIVILLFT | LPEKLPSSRG | SSEQRKASSG | LLDWATVQDR | FPWSVLFLLG | GGFALAAGVK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ESGLSHDIGA | IMRYLDVFNH | NIIMLICIII | SVTLTNVCSN | TVIASIFIPI | VAELARSLEI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DPLNFMLPVT | ISASFAFLLP | VATPPNAIVF | SSGYLKVFDM | FVSGLCVTLG | CVVLSMLNML |
| 550 | 560 | 570 | 580 | ||
| LWAGFVFNLH | LFPQWAANPS | PPLDVQDWAV | ENNITFVGTS | KL |