Q93459

PR
Gene name
nubp-1
Protein name
Cytosolic Fe-S cluster assembly factor NUBP1 homolog
Names
Nucleotide binding protein 1 homolog
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F10G8.6
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q93459

Entry ID Method Resolution Chain Position Source
AF-Q93459-F1 Predicted AlphaFoldDB

No variants for Q93459

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q93459

No associated diseases with Q93459

2 regional properties for Q93459

Type Name Position InterPro Accession
conserved_site Mrp, conserved site 166 - 182 IPR000808
domain AAA+ ATPase domain 58 - 213 IPR003593

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell projection
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cilium A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

5 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent FeS chaperone activity Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis.
iron-sulfur cluster binding Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.
metal ion binding Binding to a metal ion.

3 GO annotations of biological process

Name Definition
cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
regulation of non-motile cilium assembly Any process that modulates the frequency, rate or extent of non-motile cilium assembly.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q24K00 NUBP1 Cytosolic Fe-S cluster assembly factor NUBP1 Bos taurus (Bovine) PR
Q6P298 nubp1 Cytosolic Fe-S cluster assembly factor nubp1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MSDVPDDANA GCPGTGSAGA GKASGCAGCP NQGSCATGQG PPPDADVPKI QDRFSRIKHK
70 80 90 100 110 120
ILILSGKGGV GKSTLTSNLA RALASDPSKQ VAILDVDICG PSQPRMMGVE DEEVHNSADG
130 140 150 160 170 180
WTPVGIQPNL TLMSIAFLLG DKNDAVIWRG ARKNGMIKQF LKDVDWGEVD YLLIDTPPGT
190 200 210 220 230 240
SDEHISLVQF LLQAGPLDGA LIVSTPQEVS LLDVRKEVSF CVKTKVPILG VVENMARFVC
250 260 270 280 290 300
PNCAHTTLLF PTSTGGAEQM CKDSNLELLA QLPLEPALAK ALDNGEDFFE TNPDSTLAKS
310
FLDLAEKVKA KLV