Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q91V81

Entry ID Method Resolution Chain Position Source
AF-Q91V81-F1 Predicted AlphaFoldDB

16 variants for Q91V81

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388879054 73 M>L No EVA
rs3388897091 81 I>N No EVA
rs3388902680 114 G>C No EVA
rs3388880827 127 D>G No EVA
rs3388879051 129 G>A No EVA
rs3388891988 162 H>N No EVA
rs3388902113 166 R>* No EVA
rs3388894646 167 A>V No EVA
rs3388886790 208 M>* No EVA
rs3388902150 213 G>E No EVA
rs3388871814 242 G>S No EVA
rs3388886836 251 V>M No EVA
rs3388889959 296 L>F No EVA
rs3388858507 325 P>L No EVA
rs3388877603 437 M>L No EVA
rs3388899476 455 S>G No EVA

No associated diseases with Q91V81

No regional properties for Q91V81

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q91V81

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
  • Upon stress response, localizes with HNRNPK in cytoplasmic aggregates of stalled translational preinitiation complexes called stress granules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
U4/U6 x U5 tri-snRNP complex A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
negative regulation of mRNA splicing, via spliceosome Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q0P5L0 RBM42 RNA-binding protein 42 Bos taurus (Bovine) PR
10 20 30 40 50 60
MASAMAGAGP APGLPVAGGP VVPGPGVGIP GKSGEERLKE MEAEMALFEQ EVLGAPVTGI
70 80 90 100 110 120
PTAVPAVPTV EAMQVPPAPV IRPIIATNTY QQVQQTLEAR AAAAATVVPP MVGGPPFVGP
130 140 150 160 170 180
VGFGPADRGH LDSPEAREAM FLRRAAVAPQ RAPILRPAFV PHVLQRADSA LSSAAGGPRP
190 200 210 220 230 240
MALRPPHQAL VGPPLPGPPG PPMMLPPMAR APGPPLGSMA ALRPPLEEPA APRELGLGLG
250 260 270 280 290 300
LGLKDKEEAV VAAAAGLEEA SAAVAVGAGG APAGPAVIGP SLPLALAMPL PEPEPLPLPL
310 320 330 340 350 360
EVVRGLLPPL RIPELLSLRP RPRPPRPEPP PGLMALEVPE PLGEDKKKGK PEKLKRCIRT
370 380 390 400 410 420
AAGSSWEDPS LLEWDADDFR IFCGDLGNEV NDDILARAFS RFPSFLKAKV IRDKRTGKTK
430 440 450 460 470
GYGFVSFKDP SDYVRAMREM NGKYVGSRPI KLRKSMWKDR NLDVVRKKQK EKKKLGLR