AiPD: Autoinhibited Protein Database

Q8WVF1

Gene name	OSCP1 (C1orf102, NOR1)
Protein name	Protein OSCP1
Names	hOSCP1, Organic solute transport protein 1, Oxidored-nitro domain-containing protein 1
Species	Homo sapiens (Human)
KEGG Pathway	hsa:127700
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

236-389 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

236-389 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q8WVF1

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8WVF1-F1	Predicted				AlphaFoldDB

287 variants for Q8WVF1

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs1429742436 CA339407107	4	R>L		No	ClinGen gnomAD
CA339407081 rs1292889460	9	L>P		No	ClinGen gnomAD
rs1488362836 CA339407083	9	L>V		No	ClinGen TOPMed gnomAD
CA339407049 rs1340386682	13	L>F		No	ClinGen TOPMed gnomAD
CA339407045 rs1274156684	14	G>D		No	ClinGen gnomAD
rs978058314 CA20729009	15	G>E		No	ClinGen TOPMed
rs766658594 CA768513	16	E>*		No	ClinGen ExAC gnomAD
rs1385304768 CA339407025	17	M>T		No	ClinGen Ensembl
CA768512 rs758591420	18	L>F		No	ClinGen ExAC gnomAD
rs201190612 CA20728999	22	D>H		No	ClinGen Ensembl
CA768510 rs763901874	23	Q>P		No	ClinGen ExAC TOPMed gnomAD
CA768511 rs763901874	23	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA339406873 rs1407757557	25	L>P		No	ClinGen gnomAD
rs1168813840 CA339406866	27	A>T		No	ClinGen gnomAD
rs11547025 CA768508	31	P>Q		No	ClinGen ESP ExAC TOPMed gnomAD
VAR_027741 rs11547025 CA768507	31	P>R		No	ClinGen UniProt ESP ExAC TOPMed dbSNP gnomAD
rs1174592927 CA339406830	32	G>E		No	ClinGen gnomAD
CA768504 rs151311655	33	D>E		No	ClinGen ESP ExAC TOPMed gnomAD
rs748897051 CA768503	34	K>E		No	ClinGen ExAC TOPMed gnomAD
CA339406818 rs1202099444	34	K>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1214340404 CA339406805	36	R>C		No	ClinGen TOPMed
rs1196567549 CA339406793	38	D>N		No	ClinGen gnomAD
CA339406552 rs1213735566	40	W>R		No	ClinGen gnomAD
TCGA novel	41	T>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339406504 rs1416567213	44	D>G		No	ClinGen TOPMed
rs757388284 CA768475	44	D>H		No	ClinGen ExAC gnomAD
rs572607037 CA768474	46	K>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA768473 rs781084547	47	R>*		No	ClinGen ExAC TOPMed gnomAD
rs754993816 CA768472	47	R>Q		No	ClinGen ExAC gnomAD
rs1365153015 CA339406465	48	V>I		No	ClinGen gnomAD
TCGA novel	49	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1367744818 CA339405772	50	N>H		No	ClinGen gnomAD
rs1166896118 CA339405750	51	D>G		No	ClinGen gnomAD
rs746783723 CA768454	52	I>V		No	ClinGen ExAC TOPMed gnomAD
CA768453 rs553056470	54	S>F		No	ClinGen 1000Genomes ExAC gnomAD
rs1169595097 CA339405689	56	M>T		No	ClinGen gnomAD
rs969767873 CA20723841	57	F>L		No	ClinGen Ensembl
rs563074314 CA768452	58	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1403825136 CA339405644	59	R>T		No	ClinGen TOPMed
rs1490772004 CA339405601	62	M>T		No	ClinGen gnomAD
rs771318760 CA768450	62	M>V		No	ClinGen ExAC TOPMed gnomAD
CA339405590 rs1249188671	63	E>K		No	ClinGen gnomAD
rs753422853 CA768448	68	P>R		No	ClinGen ExAC gnomAD
CA339405497 rs1274427405	69	Q>*		No	ClinGen gnomAD
rs373258386 CA768446	70	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs373258386 CA339405484	70	E>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs768117356 CA768444	72	Y>F		No	ClinGen ExAC TOPMed gnomAD
rs768117356 CA768445	72	Y>S		No	ClinGen ExAC TOPMed gnomAD
CA768443 rs186694883	73	S>C		No	ClinGen 1000Genomes ExAC gnomAD
rs1184367836 CA339405423	74	K>N		No	ClinGen gnomAD
CA768442 rs182337804	74	K>R		No	ClinGen 1000Genomes ExAC gnomAD
CA339405419 rs1444303851	75	K>E		No	ClinGen gnomAD
rs1254146105 CA339405416	75	K>T		No	ClinGen gnomAD
CA768441 rs369020817	76	A>T		No	ClinGen ESP ExAC TOPMed
CA768438 rs770134126	80	V>I		No	ClinGen ExAC gnomAD
rs1412800249 CA339405354	81	Y>C		No	ClinGen TOPMed gnomAD
rs1412800249 CA339405353	81	Y>F		No	ClinGen TOPMed gnomAD
CA768436 rs201381707	82	E>G		No	ClinGen ExAC TOPMed gnomAD
rs145212649 CA768435	83	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA768433 rs144226900	83	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA768434 rs144226900	83	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1283221807 CA339405307	85	A>G		No	ClinGen TOPMed
CA20723779 rs756663980	85	A>P		No	ClinGen ExAC gnomAD
rs756663980 CA768432	85	A>T		No	ClinGen ExAC gnomAD
CA768431 rs368502494	86	H>R		No	ClinGen ESP ExAC TOPMed gnomAD
rs1246237800 CA339405296	86	H>Y		No	ClinGen gnomAD
CA20723764 rs760388357	88	S>Y		No	ClinGen Ensembl
rs755740191 CA768429	93	N>K		No	ClinGen ExAC gnomAD
rs973515410 CA20723735	94	Q>E		No	ClinGen TOPMed
CA339405210 rs1204796810	94	Q>P		No	ClinGen gnomAD
rs1326122701 CA339405205	95	A>T		No	ClinGen gnomAD
rs1403739444 CA339405186	97	M>R		No	ClinGen TOPMed
rs1470845360 CA339405190	97	M>V		No	ClinGen TOPMed
rs753081230 CA768428	98	D>G		No	ClinGen ExAC gnomAD
CA339405173 rs1223577856	99	K>*		No	ClinGen gnomAD
rs767733052 CA768427	99	K>M		No	ClinGen ExAC gnomAD
rs767733052 CA339405172	99	K>T		No	ClinGen ExAC gnomAD
rs771698761 CA768416	101	Y>*		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	102	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA768415 rs202016130	105	T>N		No	ClinGen 1000Genomes ExAC gnomAD
rs770900052 CA768414	106	M>L		No	ClinGen ExAC gnomAD
rs748844782 CA768412	106	M>T		No	ClinGen ExAC gnomAD
rs770900052 CA768413	106	M>V		No	ClinGen ExAC gnomAD
rs777215154 CA768411	108	F>L		No	ClinGen ExAC gnomAD
rs139145594 CA768410	110	Y>H		No	ClinGen ESP ExAC TOPMed gnomAD
rs755279719 CA768409	111	Q>H		No	ClinGen ExAC TOPMed gnomAD
rs781626400 CA768408	112	V>I		No	ClinGen ExAC TOPMed
rs751944917 CA768406	115	C>Y		No	ClinGen ExAC gnomAD
CA768405 rs766831925	116	P>A		No	ClinGen ExAC gnomAD
CA339420980 rs1164982562	117	R>*		No	ClinGen gnomAD
rs142000188 CA768403	117	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs142000188 CA768404	117	R>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs146099595 CA768402	119	K>R		No	ClinGen ESP ExAC gnomAD
CA339420894 rs1244136796	122	L>V		No	ClinGen gnomAD
rs1038126675 CA20745179	123	L>R		No	ClinGen TOPMed
rs1359075675 CA339420861	125	T>A		No	ClinGen gnomAD
rs762135024 CA768401	127	N>S		No	ClinGen ExAC TOPMed gnomAD
rs759316663 CA768398	132	I>L		No	ClinGen ExAC TOPMed gnomAD
CA339420729 rs1312598755	133	K>E		No	ClinGen TOPMed
CA339420696 rs1366897149	135	F>C		No	ClinGen gnomAD
CA768396 rs770874928	135	F>L		No	ClinGen ExAC TOPMed gnomAD
CA768395 rs749183092	137	R>*		No	ClinGen ExAC TOPMed gnomAD
CA768394 rs777268483	137	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs769235150 CA768393	138	D>G		No	ClinGen ExAC gnomAD
CA339420662 rs1444020145	138	D>N		No	ClinGen TOPMed
VAR_056958 rs34409118 CA768390	141	T>A		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs766674301 CA768388	142	I>M		No	ClinGen ExAC TOPMed gnomAD
rs754625448 CA768389	142	I>V		No	ClinGen ExAC gnomAD
TCGA novel	143	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs780420977 CA768387	143	L>P		No	ClinGen ExAC gnomAD
CA339420546 rs1269909149	144	Q>*		No	ClinGen gnomAD
rs1051732424 CA20745055	144	Q>H		No	ClinGen TOPMed gnomAD
rs1035063279 CA20745066	144	Q>L		No	ClinGen Ensembl
rs759008005 CA768386	145	Q>*		No	ClinGen ExAC TOPMed gnomAD
rs762043052 CA339420445	148	E>D		No	ClinGen ExAC TOPMed gnomAD
CA339420449 rs1457418004	148	E>G		No	ClinGen TOPMed
CA768384 rs765420878	148	E>K		No	ClinGen ExAC TOPMed gnomAD
CA768382 rs753948955	149	T>I		No	ClinGen ExAC gnomAD
CA768380 rs568837298	150	L>V		No	ClinGen 1000Genomes ExAC gnomAD
rs141201826 CA768378	151	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA768379 rs774044342	151	R>W		No	ClinGen ExAC TOPMed gnomAD
rs1386822449 CA339420303	154	T>I		No	ClinGen Ensembl
TCGA novel	155	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA768358 rs765205202	156	I>M		No	ClinGen ExAC gnomAD
rs1309972412 CA339420118	156	I>T		No	ClinGen TOPMed
rs772957430 CA768359	156	I>V		No	ClinGen ExAC gnomAD
CA20744588 rs777198609	157	Y>C		No	ClinGen TOPMed
CA339420105 rs1242367113	157	Y>D		No	ClinGen TOPMed
rs539778629 CA768357	158	G>D		No	ClinGen 1000Genomes ExAC gnomAD
rs1570521592 CA339420062	159	G>D		No	ClinGen Ensembl
TCGA novel	160	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA339420009 rs1316920110	162	A>T		No	ClinGen gnomAD
rs150943653 CA768354	164	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA339419948 rs1461767006	165	F>C		No	ClinGen gnomAD
CA768352 rs373786872	169	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs569111580 CA768353 COSM1342319 COSM1342320	169	R>W	Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC NCI-TCGA gnomAD
CA20744527 rs773468810	170	Q>*		No	ClinGen Ensembl
rs746276623 CA768351	171	T>I		No	ClinGen ExAC gnomAD
CA768348 rs550353114	174	I>F		No	ClinGen 1000Genomes TOPMed gnomAD
CA768349 rs550353114	174	I>V		No	ClinGen 1000Genomes TOPMed gnomAD
rs779402031 CA339419686	180	H>Q		No	ClinGen ExAC gnomAD
CA339419680 rs1420935726	181	I>V		No	ClinGen TOPMed
rs757734143 CA768346	182	R>*		No	ClinGen ExAC TOPMed gnomAD
rs749734102 CA339419660	182	R>L		No	ClinGen ExAC TOPMed gnomAD
rs749734102 CA768345	182	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA339417533 rs1384568854	183	V>G		No	ClinGen gnomAD
rs1243046445 CA339417546 COSM224157	183	V>I	skin [Cosmic]	No	ClinGen cosmic curated gnomAD
CA339417527 rs1204731584	184	S>F		No	ClinGen gnomAD
rs1314267212 CA339417518	185	M>V		No	ClinGen gnomAD
rs1223370177 CA339417448	190	K>E		No	ClinGen gnomAD
rs1351661519 CA339417414	192	Q>E		No	ClinGen gnomAD
CA339417407 rs1311646423	192	Q>R		No	ClinGen gnomAD
rs372876354 CA768281	194	N>D		No	ClinGen ESP ExAC TOPMed gnomAD
CA768280 rs777180611	194	N>S		No	ClinGen ExAC gnomAD
rs138506112 CA339417341	196	G>C		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	196	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA768278 rs138506112	196	G>S		No	ClinGen ESP ExAC TOPMed gnomAD
CA768277 rs149060854	197	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD
CA339417323 rs1381747301	197	R>H		No	ClinGen TOPMed gnomAD
CA20739081 rs1005351722	201	P>L		No	ClinGen TOPMed
rs901942787 CA20739055	202	V>A		No	ClinGen Ensembl
TCGA novel	202	V>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs756028464 CA768273	204	G>R		No	ClinGen ExAC gnomAD
rs1375707094 CA339417198	205	P>T		No	ClinGen gnomAD
CA768271 rs781313667	207	P>S		No	ClinGen ExAC gnomAD
TCGA novel	210	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1215519694 CA339417092	210	T>S		No	ClinGen TOPMed gnomAD
rs1354985286 CA339417049	212	V>A		No	ClinGen TOPMed
CA768270 rs754942961	213	P>A		No	ClinGen ExAC TOPMed gnomAD
CA339417024 rs1288403761	215	L>H		No	ClinGen gnomAD
CA768269 rs751102022	216	I>M		No	ClinGen ExAC gnomAD
rs1007524321 CA20739011	216	I>T		No	ClinGen Ensembl
rs1223823341 CA339416837	218	M>T		No	ClinGen gnomAD
rs1305745796 CA339416686 COSM1218950	223	G>C	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
CA339416683 rs1294707344	223	G>D		No	ClinGen gnomAD
CA768252 rs754996087	225	E>A		No	ClinGen ExAC gnomAD
CA768253 rs781084723	225	E>Q		No	ClinGen ExAC
rs762440629 CA20738669	227	K>*		No	ClinGen Ensembl
TCGA novel	227	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA768251 rs371086943	227	K>R		No	ClinGen ESP ExAC gnomAD
rs1416840 CA768250	229	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1404009959 CA339416519	230	E>G		No	ClinGen gnomAD
CA768249 rs757905867	233	H>R		No	ClinGen ExAC gnomAD
CA339416424 rs1364948246	234	G>A		No	ClinGen gnomAD
rs910630258 CA20738655	234	G>S		No	ClinGen Ensembl
CA768248 rs749945990	235	G>R		No	ClinGen ExAC TOPMed gnomAD
CA339416397 rs1240871404	236	N>S		No	ClinGen TOPMed
TCGA novel	240	A>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs986210626 CA20738633	240	A>T		No	ClinGen Ensembl
VAR_027742 CA20738661 rs2359016	242	K>E		No	ClinGen UniProt Ensembl dbSNP
CA768247 rs764909849	243	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs756885060 CA768246	244	G>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA339416100 rs1197698787	249	Y>F		No	ClinGen gnomAD
rs754226924 CA768245	249	Y>H		No	ClinGen ExAC gnomAD
TCGA novel	249	Y>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs761252936 CA768243	252	R>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA768244 rs761252936	252	R>G		No	ClinGen ExAC TOPMed gnomAD
COSM77373 CA768242 rs753198894	252	R>Q	ovary [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA339416058 rs1368609358	253	V>D		No	ClinGen TOPMed
CA339416061 rs1479675148	253	V>I		No	ClinGen gnomAD
rs1250692472 CA339416029	256	L>P		No	ClinGen gnomAD
rs1305290068 CA339415987	259	N>I		No	ClinGen TOPMed
CA20738572 rs373081087	260	M>K		No	ClinGen ESP
rs17442970 CA768226	263	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs17442970 CA768227	263	V>M		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1287322283 CA339415813	265	Q>*		No	ClinGen TOPMed
rs1236361726 CA339415730	270	H>P		No	ClinGen gnomAD
CA768222 rs767954254	274	S>T		No	ClinGen ExAC gnomAD
rs751718991 CA768220	276	K>Q		No	ClinGen ExAC gnomAD
CA768218 rs763280071	278	L>S		No	ClinGen ExAC gnomAD
CA339415549 rs1304944200	279	A>G		No	ClinGen gnomAD
rs1049019255 CA20738312	280	S>L		No	ClinGen TOPMed
CA339415502 rs1570501063	281	W>R		No	ClinGen Ensembl
rs547852096 CA20738309	282	T>A		No	ClinGen 1000Genomes gnomAD
rs547852096 CA339415476	282	T>P		No	ClinGen 1000Genomes gnomAD
rs1253602336 CA339414388	284	E>D		No	ClinGen TOPMed
TCGA novel	284	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA768203 rs202237610	286	I>S		No	ClinGen ExAC TOPMed gnomAD
CA339414349 rs1570498349	288	P>S		No	ClinGen Ensembl
CA339414315 rs1162993844	291	L>H		No	ClinGen gnomAD
CA768201 rs758620253	293	K>E		No	ClinGen ExAC TOPMed gnomAD
CA20737547 rs925041588	294	E>*		No	ClinGen gnomAD
rs750501736 CA768200	296	L>M		No	ClinGen ExAC TOPMed gnomAD
rs1263460054 CA339414227	299	L>S		No	ClinGen gnomAD
rs765427269 CA768199	303	M>T		No	ClinGen ExAC gnomAD
CA339414175 rs1341812616	304	G>E		No	ClinGen TOPMed gnomAD
CA339414149 CA339414152 rs1290481254	306	M>I		No	ClinGen TOPMed gnomAD
CA768198 rs762046311	307	E>Q		No	ClinGen ExAC gnomAD
rs140749623 CA768197	307	E>V		No	ClinGen ESP ExAC gnomAD
rs767280774 CA768196	308	I>V		No	ClinGen ExAC gnomAD
CA768195 rs759486383	311	P>L		No	ClinGen ExAC gnomAD
CA20737510 rs1036098759	313	G>S		No	ClinGen TOPMed
CA768193 rs2275477	317	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA768192 rs748843097	318	F>L		No	ClinGen ExAC gnomAD
rs748893476 CA768191	319	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1406005863 CA339414026	319	R>W	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA339414017 rs1166015570	320	L>S		No	ClinGen gnomAD
CA339413959 rs199901207	324	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs199901207 CA768189	324	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA339413947 rs1458987459	325	T>I		No	ClinGen TOPMed
CA768186 rs148013964	326	D>N		No	ClinGen ESP ExAC TOPMed gnomAD
CA768185 rs186698173	330	E>K		No	ClinGen 1000Genomes ExAC gnomAD
CA768163 rs567565665	333	A>V		No	ClinGen 1000Genomes ExAC gnomAD
rs756278342 CA768160	339	E>*		No	ClinGen ExAC
TCGA novel	340	L>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs374472163 CA768158	342	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
CA768157 rs762890061	344	V>I		No	ClinGen ExAC TOPMed gnomAD
CA339413455 rs1377580266	347	I>M		No	ClinGen gnomAD
rs1304447407 CA339413463	347	I>V		No	ClinGen TOPMed
rs1570495217 CA339413423	350	T>P		No	ClinGen Ensembl
CA768128 rs771851049	355	R>Q		No	ClinGen ExAC gnomAD
CA768129 rs148820896	355	R>W		No	ClinGen ESP ExAC TOPMed gnomAD
CA339413214 rs1229854981	357	E>D		No	ClinGen gnomAD
rs372240068 CA768127	357	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA768126 rs774526032	358	E>K		No	ClinGen ExAC TOPMed gnomAD
CA768125 rs771495318	358	E>V		No	ClinGen ExAC TOPMed gnomAD
CA768124 rs749688697	359	L>Q		No	ClinGen ExAC TOPMed gnomAD
rs1341955121 CA339413192	360	A>S		No	ClinGen TOPMed gnomAD
rs1341955121 CA339413193	360	A>T		No	ClinGen TOPMed gnomAD
CA20736141 rs552863417	361	R>*		No	ClinGen TOPMed gnomAD
CA20736147 rs552863417	361	R>G		No	ClinGen TOPMed gnomAD
rs769918188 CA768122	361	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs748219697 CA768121	362	I>V		No	ClinGen ExAC gnomAD
CA768120 rs781432899	365	E>K		No	ClinGen ExAC gnomAD
rs755132364 CA768119	366	F>S		No	ClinGen ExAC gnomAD
CA339413085 rs778532589	368	I>M		No	ClinGen ExAC gnomAD
CA768116 rs757225346	369	T>M		No	ClinGen ExAC gnomAD
rs1286980837 CA339413070	370	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs1452991218 CA339413053	371	Q>K		No	ClinGen TOPMed
rs755756324 CA768113	373	R>K		No	ClinGen ExAC
rs1247222519 CA339413021	373	R>S		No	ClinGen TOPMed gnomAD
CA768111 rs151147935	375	S>I		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA768109 rs151147935	375	S>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA768110 rs151147935	375	S>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA339412991 rs1394685771	376	T>N		No	ClinGen TOPMed
CA20736035 rs17851612	377	S>G		No	ClinGen Ensembl
CA768107 rs556610510	377	S>N		No	ClinGen 1000Genomes ExAC gnomAD
rs773773589 CA768106	379	G>E		No	ClinGen ExAC TOPMed gnomAD
rs776644354 CA768103	381	D>N		No	ClinGen ExAC TOPMed gnomAD
CA339412933 rs776644354	381	D>Y		No	ClinGen ExAC TOPMed gnomAD
CA768102 rs747136536	384	A>S		No	ClinGen ExAC gnomAD
CA768101 rs747136536	384	A>T		No	ClinGen ExAC gnomAD
CA768100 rs374436783	385	M>V		No	ClinGen ESP ExAC gnomAD
CA768099 rs757060476	387	D>N		No	ClinGen ExAC gnomAD
rs371467203 CA768098	388	E>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs763283490 CA768095	390	L>A		No	ClinGen ExAC gnomAD
CA768096 rs759325013	390	L>Q		No	ClinGen ExAC TOPMed gnomAD

No associated diseases with Q8WVF1

No regional properties for Q8WVF1

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q8WVF1

Functions

		Description
EC Number
Subcellular Localization	Basal cell membrane	Syncytiotrophoblast in placenta
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

3 GO annotations of cellular component

Name	Definition
basal plasma membrane	The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name	Definition
transmembrane transporter activity	Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name	Definition
xenobiotic detoxification by transmembrane export across the plasma membrane	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.

3 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q29S00	OSCP1	Protein OSCP1	Bos taurus (Bovine)	PR
Q8BHW2	Oscp1	Protein OSCP1	Mus musculus (Mouse)	PR
Q4QQS3	Oscp1	Protein OSCP1	Rattus norvegicus (Rat)	PR

10	20	30	40	50	60
MSVRTLPLLF	LNLGGEMLYI	LDQRLRAQNI	PGDKARKDEW	TEVDRKRVLN	DIISTMFNRK
70	80	90	100	110	120
FMEELFKPQE	LYSKKALRTV	YERLAHASIM	KLNQASMDKL	YDLMTMAFKY	QVLLCPRPKD
130	140	150	160	170	180
VLLVTFNHLD	TIKGFIRDSP	TILQQVDETL	RQLTEIYGGL	SAGEFQLIRQ	TLLIFFQDLH
190	200	210	220	230	240
IRVSMFLKDK	VQNNNGRFVL	PVSGPVPWGT	EVPGLIRMFN	NKGEEVKRIE	FKHGGNYVPA
250	260	270	280	290	300
PKEGSFELYG	DRVLKLGTNM	YSVNQPVETH	VSGSSKNLAS	WTQESIAPNP	LAKEELNFLA
310	320	330	340	350	360
RLMGGMEIKK	PSGPEPGFRL	NLFTTDEEEE	QAALTRPEEL	SYEVINIQAT	QDQQRSEELA
370	380
RIMGEFEITE	QPRLSTSKGD	DLLAMMDEL