Q8BHW2

PR
Gene name
Oscp1
Protein name
Protein OSCP1
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:230751
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

223-379 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8BHW2

Entry ID Method Resolution Chain Position Source
AF-Q8BHW2-F1 Predicted AlphaFoldDB

21 variants for Q8BHW2

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388710392 10 F>L No EVA
rs3388712101 15 G>V No EVA
rs3388713136 122 I>V No EVA
rs3388717230 130 P>S No EVA
rs258907874 132 V>I No EVA
rs3388709355 156 Q>H No EVA
rs249352442 157 L>Q No EVA
rs3388708872 160 Q>H No EVA
rs264095831 164 N>I No EVA
rs3388689827 209 F>I No EVA
rs265260962 263 A>T No EVA
rs3388712109 274 E>D No EVA
rs3388698842 304 P>S No EVA
rs27550210 306 P>L No EVA
rs3388699331 329 E>K No EVA
rs27550198 336 S>N No EVA
rs228327930 362 L>P No EVA
rs3388708856 367 S>I No EVA
rs3388708837 369 G>R No EVA
rs3388703349 374 A>V No EVA
rs3388689809 378 R>S No EVA

No associated diseases with Q8BHW2

No regional properties for Q8BHW2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8BHW2

Functions

Description
EC Number
Subcellular Localization
  • Basal cell membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
basal plasma membrane The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
xenobiotic detoxification by transmembrane export across the plasma membrane A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q29S00 OSCP1 Protein OSCP1 Bos taurus (Bovine) PR
Q8WVF1 OSCP1 Protein OSCP1 Homo sapiens (Human) PR
Q4QQS3 Oscp1 Protein OSCP1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MSVRTLPLLF LNLGGEMLYV LDQRLRAQNI PGDKARKVLN DIISTMFNRK FMDELFKPQE
70 80 90 100 110 120
LYSKKALRTV YDRLAHASIM RLNQASMDKL YDLMTMAFKY QVLLCPRPKD VLLVTFNHLD
130 140 150 160 170 180
AIKGFVQDSP TVIHQVDETF RQLSEVYGKL SEGEFQLIRQ TLLNFFQDLH IRVSTFLKDK
190 200 210 220 230 240
VQNSNGRFVL PVSGPVPWGT EVPGVIRVFS VKGKEVKKMK FRHGGDYVAA QKEGSFELYG
250 260 270 280 290 300
DRVLKLGTNM YSASRPVETH MSATSKNAAS RAQENIVPNP LAKEELNFLA RLMGGMEIKK
310 320 330 340 350 360
PSGPEPGFRL NLFTTDEEEE HAALSRPEEL SYEVISIQAT QDQQRNEELA RIMGEFEITE
370
QLEQNTSKGD DLLAMMDRL