Q8WV83
PR
Gene name |
SLC35F5 (NS5ATP3, UNQ2545/PRO6097) |
Protein name |
Solute carrier family 35 member F5 |
Names |
Hepatitis C virus NS5A-transactivated protein 3, HCV NS5A-transactivated protein 3 |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:80255 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8WV83
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8WV83-F1 | Predicted | AlphaFoldDB |
403 variants for Q8WV83
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs993440126 CA53769241 |
3 | P>R | No |
ClinGen TOPMed gnomAD |
|
|
rs1259863213 CA348322750 |
4 | P>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs754749282 CA53769226 |
6 | R>C | No |
ClinGen Ensembl |
|
|
rs1458361319 CA348322739 |
6 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
rs1458361319 CA348322737 |
6 | R>L | No |
ClinGen TOPMed gnomAD |
|
|
CA348322732 rs1367133870 |
7 | H>R | No |
ClinGen gnomAD |
|
|
rs1166480520 CA348322723 |
8 | R>H | No |
ClinGen gnomAD |
|
|
rs866739866 CA53769217 |
9 | G>W | No |
ClinGen Ensembl |
|
|
CA348322715 rs1448709483 |
10 | A>S | No |
ClinGen gnomAD |
|
|
CA1842321 rs747889243 |
10 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA1842320 rs776157522 |
11 | G>E | No |
ClinGen ExAC gnomAD |
|
|
rs768142063 CA1842319 |
12 | R>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs768142063 CA53769204 |
12 | R>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348322704 CA53769187 rs866291136 |
12 | R>S | No |
ClinGen gnomAD |
|
|
rs771560952 CA1842299 |
14 | G>E | No |
ClinGen ExAC gnomAD |
|
|
CA1842297 rs778071602 |
15 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53768636 rs778071602 |
15 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs368464948 CA1842295 |
17 | S>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1842296 rs368464948 |
17 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs781451090 CA1842294 |
20 | P>L | No |
ClinGen ExAC gnomAD |
|
|
CA348322585 rs1368280063 |
21 | P>L | No |
ClinGen gnomAD |
|
|
CA53768616 TCGA novel rs755230058 |
22 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC gnomAD NCI-TCGA |
|
CA1842292 rs751631370 |
23 | R>S | No |
ClinGen ExAC TOPMed |
|
|
CA53768610 rs1023368383 |
25 | R>* | No |
ClinGen Ensembl |
|
|
rs766499217 CA1842291 |
25 | R>I | No |
ClinGen ExAC gnomAD |
|
|
rs758486121 CA1842290 |
26 | S>C | No |
ClinGen ExAC gnomAD |
|
|
CA1842289 rs750307878 |
28 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
CA1842288 rs180746065 |
28 | K>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs200368608 CA1842287 |
29 | F>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs867595280 CA53768572 |
31 | G>D | No |
ClinGen TOPMed gnomAD |
|
|
rs375731808 CA1842286 |
31 | G>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA348322527 rs867595280 |
31 | G>V | No |
ClinGen TOPMed gnomAD |
|
|
CA1842284 rs577560893 |
32 | I>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs577560893 CA348322526 |
32 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA53768546 rs373231334 |
33 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ESP NCI-TCGA TOPMed |
|
CA1842282 rs771654867 |
35 | E>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs758976655 CA1842281 |
37 | L>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53768540 rs113680446 |
37 | L>H | No |
ClinGen gnomAD |
|
|
CA348322492 rs113680446 |
37 | L>P | No |
ClinGen gnomAD |
|
|
CA348322473 rs1467658680 |
40 | A>D | No |
ClinGen TOPMed |
|
|
rs770227498 CA1842279 |
42 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs748511456 CA1842278 |
43 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs781600606 CA1842277 |
44 | R>K | No |
ClinGen ExAC gnomAD |
|
|
rs777862070 CA348322428 |
46 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA1842249 rs777862070 |
46 | Q>E | No |
ClinGen ExAC gnomAD |
|
|
CA1842246 rs190986421 |
47 | M>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA1842245 rs754651084 |
47 | M>T | No |
ClinGen ExAC gnomAD |
|
|
CA1842247 rs190986421 |
47 | M>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs995624580 CA348322415 COSM1185983 |
48 | V>L | lung [Cosmic] | No |
ClinGen cosmic curated TOPMed gnomAD |
|
rs995624580 CA53768221 |
48 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs751063460 CA1842244 |
49 | C>Y | No |
ClinGen ExAC gnomAD |
|
|
rs143143202 CA1842243 |
50 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1842242 rs762525763 |
51 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs201324940 CA53768211 |
52 | V>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs201324940 CA1842241 |
52 | V>D | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA348322387 rs201703620 |
53 | M>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs201703620 CA1842239 |
53 | M>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs775870472 CA348322368 |
55 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs775870472 CA1842238 |
55 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA53768200 rs912536506 |
56 | M>V | No |
ClinGen gnomAD |
|
|
rs1397190432 CA348322353 |
57 | N>K | No |
ClinGen TOPMed |
|
|
rs1234776215 CA348322355 |
57 | N>S | No |
ClinGen gnomAD |
|
|
rs1208308821 CA348322339 |
59 | Q>H | No |
ClinGen gnomAD |
|
|
CA53768196 rs928763263 |
62 | G>S | No |
ClinGen TOPMed |
|
|
CA1842236 rs111569665 |
64 | T>A | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs111569665 CA1842235 |
64 | T>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
| TCGA novel | 65 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1842234 rs770852991 |
68 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348322270 rs1574280089 |
70 | A>T | No |
ClinGen Ensembl |
|
|
CA1842233 rs749413468 |
70 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs748206952 CA1842232 |
74 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs1451482651 CA348322246 |
74 | V>I | No |
ClinGen gnomAD |
|
|
CA1842230 rs747948946 |
75 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756172527 CA1842231 |
75 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1574280010 CA348322223 |
78 | L>F | No |
ClinGen Ensembl |
|
|
CA348322221 rs1251212759 |
78 | L>P | No |
ClinGen TOPMed |
|
|
rs1159780832 CA348322208 |
80 | D>V | No |
ClinGen gnomAD |
|
|
rs970005330 CA53768150 |
81 | V>M | No |
ClinGen TOPMed |
|
|
rs1207724157 COSM714679 CA348322200 |
82 | I>V | lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA1842225 rs754811607 |
83 | W>C | No |
ClinGen ExAC gnomAD |
|
|
CA1842226 rs780904923 |
83 | W>L | No |
ClinGen ExAC gnomAD |
|
|
CA348322186 rs1255862843 |
84 | V>I | No |
ClinGen TOPMed |
|
|
CA1842224 rs186083549 |
85 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs531095565 CA1842223 |
86 | S>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA348322167 rs1415994938 |
87 | S>Y | No |
ClinGen TOPMed |
|
|
rs1335220758 CA348322164 COSM441026 |
88 | E>K | Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA348322145 rs1294957195 |
90 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
CA1842222 rs757797501 |
91 | S>L | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 92 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348322116 rs1225740105 |
93 | V>A | No |
ClinGen gnomAD |
|
|
rs778454228 CA1842203 |
93 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA348322103 rs1295666922 |
95 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
CA348322091 rs1559363978 |
97 | Y>H | No |
ClinGen Ensembl |
|
|
rs143352356 CA1842202 |
98 | N>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1302516663 CA348322067 |
100 | P>S | No |
ClinGen gnomAD |
|
|
CA348322053 rs1574270877 |
102 | F>I | No |
ClinGen Ensembl |
|
|
rs796152865 CA53766064 |
104 | T>A | No |
ClinGen gnomAD |
|
|
rs759775573 CA1842199 |
107 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs759775573 CA53766061 |
107 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
CA348322013 rs1299522740 |
108 | T>A | No |
ClinGen TOPMed |
|
|
CA1842196 rs763321727 |
110 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs766483024 CA1842197 |
110 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1265832767 CA348321984 |
112 | V>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1265832767 CA348321982 |
112 | V>G | No |
ClinGen TOPMed gnomAD |
|
|
rs769924613 CA1842194 |
114 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1221298649 CA348321956 |
116 | L>F | No |
ClinGen TOPMed |
|
|
CA1842193 rs762012252 |
119 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1488097560 CA348321903 |
124 | W>R | No |
ClinGen TOPMed |
|
|
rs1228946220 CA348321847 |
131 | G>A | No |
ClinGen gnomAD |
|
|
COSM1005734 CA1842190 rs184692931 |
133 | R>C | large_intestine endometrium [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
CA1842189 rs556190555 |
133 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs184692931 CA348321838 |
133 | R>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs375944618 CA1842187 |
134 | G>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1559363591 CA348321821 |
136 | H>D | No |
ClinGen Ensembl |
|
|
rs1390668273 CA348321819 |
136 | H>P | No |
ClinGen gnomAD |
|
|
CA348321818 rs1390668273 |
136 | H>R | No |
ClinGen gnomAD |
|
|
rs1395997952 CA348321807 |
138 | A>P | No |
ClinGen gnomAD |
|
|
CA1842185 rs778542123 |
138 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756717732 CA1842184 |
139 | F>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs976137726 CA53763870 |
140 | F>L | No |
ClinGen TOPMed gnomAD |
|
|
rs370045540 CA348321776 |
141 | A>S | No |
ClinGen ESP ExAC gnomAD |
|
|
rs370045540 CA1842157 |
141 | A>T | No |
ClinGen ESP ExAC gnomAD |
|
|
rs765524202 CA1842156 |
142 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348321767 rs1266128303 |
142 | D>V | No |
ClinGen gnomAD |
|
|
CA348321754 rs1351059508 |
144 | E>V | No |
ClinGen gnomAD |
|
|
rs1559357689 CA348321729 |
148 | A>T | No |
ClinGen Ensembl |
|
|
rs376438996 CA1842154 |
149 | A>P | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs376438996 CA1842153 |
149 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1314690806 CA348321707 |
151 | T>I | No |
ClinGen gnomAD |
|
|
rs976750985 CA53763799 |
153 | D>A | No |
ClinGen TOPMed |
|
|
CA1842151 rs760677524 |
154 | T>A | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA1842150 rs147851917 |
154 | T>I | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs147851917 CA348321689 |
154 | T>R | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs767465877 CA1842149 |
156 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs1168644855 CA348321673 |
157 | N>D | No |
ClinGen TOPMed |
|
|
rs1559357534 CA348321653 |
159 | S>F | No |
ClinGen Ensembl |
|
|
rs1018489686 CA53763770 |
160 | L>S | No |
ClinGen TOPMed gnomAD |
|
|
CA348321628 rs1423072415 |
161 | S>R | No |
ClinGen gnomAD |
|
|
CA1842134 rs764255442 |
163 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1559353989 CA348321617 |
163 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs764255442 CA53762193 |
163 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769700552 CA53762175 |
166 | V>A | No |
ClinGen Ensembl |
|
|
rs1451612481 CA348321599 |
166 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
rs377392317 CA1842132 |
171 | H>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs767414905 CA1842130 |
172 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA348321561 rs1231351785 |
172 | D>N | No |
ClinGen TOPMed |
|
|
rs767414905 CA348321557 |
172 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA348321538 rs1559353868 |
175 | S>T | No |
ClinGen Ensembl |
|
|
rs759539558 CA1842129 |
176 | E>G | No |
ClinGen ExAC gnomAD |
|
|
CA1842128 rs774122553 |
178 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1197229396 CA348321501 |
180 | S>I | No |
ClinGen gnomAD |
|
|
CA1842126 rs545001610 |
183 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA1842127 rs766127685 |
183 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs373074565 CA1842125 |
185 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA348321449 rs1187962394 |
188 | T>A | No |
ClinGen gnomAD |
|
|
rs139852762 CA53761476 |
188 | T>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs139852762 CA1842108 |
188 | T>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs573518732 CA53761473 |
189 | P>A | No |
ClinGen 1000Genomes |
|
|
CA1842107 rs750222499 |
189 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs764937717 CA1842106 |
190 | K>R | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 192 | S>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs761613867 CA1842105 |
193 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA1842104 rs776435612 |
193 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA53761453 rs776435612 |
193 | R>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs947208204 CA53761439 |
194 | V>M | No |
ClinGen TOPMed |
|
|
CA53761404 rs938619924 |
197 | S>R | No |
ClinGen Ensembl |
|
|
rs774872803 CA1842101 |
198 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA348321377 rs908499067 |
198 | N>I | No |
ClinGen TOPMed gnomAD |
|
|
CA53761380 rs908499067 |
198 | N>S | No |
ClinGen TOPMed gnomAD |
|
|
rs200273801 CA1842100 |
199 | I>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs778068628 CA1842098 |
200 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1240306841 CA348321354 |
201 | E>D | No |
ClinGen gnomAD |
|
|
CA348321344 rs1201832503 |
203 | R>* | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA348321345 rs1201832503 |
203 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1460946211 CA348321343 |
203 | R>Q | No |
ClinGen gnomAD |
|
|
rs1264259641 CA348321335 |
204 | Q>L | No |
ClinGen gnomAD |
|
|
CA53761359 rs989985832 |
205 | L>F | No |
ClinGen TOPMed |
|
|
CA1842097 rs149790536 |
206 | P>L | No |
ClinGen ESP ExAC gnomAD |
|
|
rs149790536 CA348321324 |
206 | P>Q | No |
ClinGen ESP ExAC gnomAD |
|
|
rs781420683 CA1842095 |
207 | S>P | No |
ClinGen ExAC |
|
| TCGA novel | 208 | S>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1046913523 CA53761309 |
209 | H>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs923962780 CA53761316 |
209 | H>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA348321287 rs1381396180 |
211 | L>W | No |
ClinGen TOPMed |
|
| TCGA novel | 214 | K>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348321251 rs1296040110 |
214 | K>Q | No |
ClinGen TOPMed |
|
|
rs779462853 CA53761286 |
216 | S>T | No |
ClinGen Ensembl |
|
|
CA348321203 rs1390434611 |
217 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA1842093 rs751684782 |
217 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA348321197 rs751684782 |
217 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs1344609876 CA348321178 COSM569335 |
218 | M>I | lung [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs750217904 CA1842090 |
218 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs758333293 CA1842091 |
218 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1842089 rs764882352 |
221 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1159526805 CA348321144 |
221 | P>T | No |
ClinGen TOPMed gnomAD |
|
|
rs368083148 CA1842086 |
223 | K>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA53761175 rs150656361 |
224 | E>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1842085 rs150656361 |
224 | E>K | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1842084 rs774904158 |
225 | Q>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771468412 CA1842083 |
225 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
rs1260693096 CA348321070 |
226 | E>* | No |
ClinGen gnomAD |
|
| TCGA novel | 228 | I>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1289086996 CA348321035 |
228 | I>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs763431237 CA1842082 |
228 | I>T | No |
ClinGen ExAC gnomAD |
|
|
CA53761144 rs964012277 |
228 | I>V | No |
ClinGen gnomAD |
|
|
rs773787189 CA1842081 |
229 | L>M | No |
ClinGen ExAC gnomAD |
|
|
rs748530443 CA1842079 |
232 | V>A | No |
ClinGen ExAC gnomAD |
|
|
CA1842078 rs776807826 |
233 | G>R | No |
ClinGen ExAC |
|
|
rs986908406 CA53761117 |
235 | L>F | No |
ClinGen Ensembl |
|
|
CA1842076 rs747084469 |
237 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs780054626 CA1842075 |
241 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 244 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs778939844 CA53761094 |
245 | F>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs778939844 CA1842072 |
245 | F>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1206966623 CA348320793 |
246 | F>L | No |
ClinGen gnomAD |
|
| rs577214214 | 247 | F>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 247 | F>missing | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| rs577214214 | 248 | C>A | Variant assessed as Somatic; 0.006786 impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1402692634 CA348320747 |
248 | C>F | No |
ClinGen TOPMed |
|
|
CA348320755 rs1424249573 |
248 | C>G | No |
ClinGen TOPMed gnomAD |
|
|
rs1166961167 CA348320712 |
250 | V>A | No |
ClinGen gnomAD |
|
|
rs1211240737 CA348320715 |
250 | V>L | No |
ClinGen gnomAD |
|
|
CA348319570 rs1187466058 |
251 | W>C | No |
ClinGen TOPMed |
|
|
CA348319500 rs1412001854 |
256 | L>F | No |
ClinGen gnomAD |
|
|
CA348319492 rs1490623233 |
257 | S>* | No |
ClinGen gnomAD |
|
|
CA348319482 rs1193722870 |
258 | Y>S | No |
ClinGen gnomAD |
|
|
rs778972826 CA1842052 |
259 | Q>* | No |
ClinGen ExAC gnomAD |
|
|
CA1842049 rs576219497 |
259 | Q>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs757302465 CA1842051 |
259 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA348319448 rs1376409842 |
261 | A>T | No |
ClinGen TOPMed |
|
|
rs755987979 CA1842048 |
264 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs1469698787 CA348319411 |
264 | D>N | No |
ClinGen TOPMed |
|
|
CA1842047 rs752229613 |
265 | T>I | No |
ClinGen ExAC |
|
|
rs767233933 CA1842046 |
267 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs141432650 CA1842045 |
269 | I>V | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA53756822 RCV000958569 CA1842044 rs148152519 |
273 | L>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD ClinVar dbSNP |
|
|
rs765726843 CA1842043 |
274 | S>F | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA348319237 rs1362999771 |
276 | T>I | No |
ClinGen TOPMed |
|
|
rs754355533 CA1842041 |
278 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 279 | L>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348318848 rs1574242545 |
281 | T>P | No |
ClinGen Ensembl |
|
|
rs1241997234 CA348318832 |
283 | I>N | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 284 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1842025 rs757906828 |
284 | L>P | No |
ClinGen ExAC gnomAD |
|
|
rs1392298538 CA348318819 |
285 | A>G | No |
ClinGen TOPMed |
|
|
CA53756323 rs928321119 |
288 | F>L | No |
ClinGen TOPMed |
|
|
rs754302593 CA1842024 |
288 | F>Y | No |
ClinGen ExAC gnomAD |
|
|
rs144617050 CA1842023 |
290 | S>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs760926158 CA1842022 |
290 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs753146033 CA1842021 |
291 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs943696639 CA53756315 |
293 | G>R | No |
ClinGen Ensembl |
|
|
rs1385069553 CA348318765 |
294 | D>N | No |
ClinGen TOPMed |
|
|
CA348318762 rs1242605342 |
294 | D>V | No |
ClinGen gnomAD |
|
|
rs766518973 CA53756314 |
295 | R>G | No |
ClinGen Ensembl |
|
|
CA348318740 rs1250663545 |
297 | T>I | No |
ClinGen TOPMed |
|
|
CA1842020 rs767630923 |
298 | L>F | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 298 | L>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771070381 CA1842017 |
302 | L>* | No |
ClinGen ExAC gnomAD |
|
|
rs763160674 CA1842016 |
303 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1841982 rs748623963 |
308 | I>T | No |
ClinGen ExAC gnomAD |
|
|
rs1401661643 CA348318459 |
310 | G>S | No |
ClinGen TOPMed |
|
|
CA348318441 rs1312183846 |
311 | V>I | No |
ClinGen gnomAD |
|
|
rs1017056763 CA1841978 |
312 | V>I | No |
ClinGen TOPMed |
|
|
rs1017056763 CA53754856 |
312 | V>L | No |
ClinGen TOPMed |
|
|
rs1257172496 CA348318403 |
313 | L>P | No |
ClinGen TOPMed |
|
|
CA348318365 rs1350875403 |
316 | L>M | No |
ClinGen TOPMed |
|
|
rs752023112 CA1841977 |
317 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA53754845 rs202119434 |
318 | G>R | No |
ClinGen gnomAD |
|
|
CA1841975 rs149050681 |
322 | P>S | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs750620734 CA348318255 |
323 | A>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs750620734 CA1841974 |
323 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765291977 CA53754841 |
325 | R>I | No |
ClinGen ExAC gnomAD |
|
|
CA1841973 rs765291977 |
325 | R>K | No |
ClinGen ExAC gnomAD |
|
|
CA348318191 rs954097624 |
327 | T>A | No |
ClinGen gnomAD |
|
|
rs954097624 CA53754840 |
327 | T>S | No |
ClinGen gnomAD |
|
| TCGA novel | 328 | V>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1359735479 CA348318177 |
328 | V>I | No |
ClinGen gnomAD |
|
| TCGA novel | 328 | V>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 329 | G>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1014373410 CA53754836 |
329 | G>S | No |
ClinGen TOPMed |
|
|
rs1159094412 CA348317669 |
331 | I>V | No |
ClinGen gnomAD |
|
|
CA1841962 rs748773975 |
335 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA348317566 rs1423345069 |
337 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
CA348317546 rs1485063307 COSM475800 |
338 | M>I | kidney [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs755585788 CA1841960 |
338 | M>T | No |
ClinGen ExAC gnomAD |
|
|
rs780505874 CA1841958 |
340 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
rs1406810776 CA348317501 |
341 | A>T | No |
ClinGen gnomAD |
|
| TCGA novel | 343 | Y>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1841956 rs563554604 |
346 | M>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs199593131 CA1841957 |
346 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs543787347 CA1841955 |
351 | V>L | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs757337626 CA53750978 |
353 | R>G | No |
ClinGen ExAC gnomAD |
|
|
rs1298555879 CA348317279 |
354 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs753904064 CA1841953 |
355 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1034807276 CA53750966 |
357 | L>S | No |
ClinGen TOPMed |
|
|
rs951884257 CA53750963 |
359 | I>S | No |
ClinGen Ensembl |
|
|
rs753184039 CA53750952 |
361 | M>K | No |
ClinGen TOPMed gnomAD |
|
|
rs760664006 CA1841951 |
361 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs574675394 CA1841950 |
362 | F>Y | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA53750943 rs921653092 |
364 | G>R | No |
ClinGen Ensembl |
|
|
rs1559328981 CA348316793 |
366 | V>I | No |
ClinGen Ensembl |
|
|
CA348316746 rs1283997587 |
373 | L>F | No |
ClinGen TOPMed |
|
|
CA1841931 rs756192632 |
373 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348316744 rs756192632 |
373 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53749166 rs140295335 |
376 | P>L | No |
ClinGen ESP TOPMed gnomAD |
|
|
rs1174926507 CA348316719 |
377 | G>D | No |
ClinGen gnomAD |
|
|
rs1206620618 CA348316722 |
377 | G>S | No |
ClinGen TOPMed |
|
|
rs767467816 CA1841929 |
380 | L>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1841928 rs556890812 |
381 | L>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs751354231 CA1841927 |
383 | Y>C | No |
ClinGen ExAC gnomAD |
|
|
CA1841925 rs762451375 |
390 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1024035038 CA53749116 |
393 | N>S | No |
ClinGen TOPMed |
|
|
rs375146485 CA53749115 |
394 | K>Q | No |
ClinGen ESP TOPMed |
|
|
rs371730492 CA1841923 |
394 | K>R | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1303705126 CA348316542 |
395 | V>I | No |
ClinGen gnomAD |
|
|
rs1180511334 CA348316520 |
396 | V>I | No |
ClinGen TOPMed |
|
|
CA1841920 rs374406239 |
398 | M>I | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA1841921 rs147832436 |
398 | M>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs112949097 CA348316454 |
399 | C>F | No |
ClinGen TOPMed |
|
|
rs112949097 CA53749078 |
399 | C>Y | No |
ClinGen TOPMed |
|
|
rs771341572 CA1841917 |
406 | I>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA53749073 rs1012163792 |
409 | V>A | No |
ClinGen Ensembl |
|
| TCGA novel | 412 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA348316350 rs1238236168 |
412 | E>D | No |
ClinGen gnomAD |
|
|
rs1438483695 CA348316357 |
412 | E>K | No |
ClinGen gnomAD |
|
|
CA348316318 rs1559328522 |
417 | W>* | No |
ClinGen Ensembl |
|
|
rs76954285 CA53749065 |
417 | W>G | No |
ClinGen Ensembl |
|
|
CA1841897 rs768064286 |
418 | G>D | No |
ClinGen ExAC gnomAD |
|
|
CA53747580 rs768064286 |
418 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA348316071 rs1284066393 |
419 | C>W | No |
ClinGen gnomAD |
|
|
rs1354343455 CA348316079 |
419 | C>Y | No |
ClinGen gnomAD |
|
|
rs1246151414 CA348316008 |
423 | S>L | No |
ClinGen gnomAD |
|
|
rs1275367057 CA348315994 |
425 | L>F | No |
ClinGen TOPMed gnomAD |
|
|
rs771150964 CA1841894 |
427 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs1360708570 CA348315975 |
428 | T>I | No |
ClinGen gnomAD |
|
|
CA348315924 rs773389335 |
432 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348315920 rs1171930420 |
433 | L>F | No |
ClinGen TOPMed |
|
|
CA1841888 rs755102738 |
439 | I>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
CA1841889 rs781312270 |
439 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA53747477 rs370710490 |
440 | I>T | No |
ClinGen TOPMed gnomAD |
|
|
rs145385669 CA1841887 |
440 | I>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1333975005 CA348315793 |
442 | D>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
CA1841886 rs780074724 |
443 | M>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1218234940 CA348315771 |
443 | M>T | No |
ClinGen gnomAD |
|
|
rs932719514 CA53747454 |
444 | C>F | No |
ClinGen gnomAD |
|
|
rs932719514 CA348315749 |
444 | C>Y | No |
ClinGen gnomAD |
|
|
CA1841884 CA348315720 rs566227182 |
445 | M>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA1841885 rs758100032 |
445 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA348315133 rs1330172075 |
448 | V>M | No |
ClinGen gnomAD |
|
|
CA348315127 rs1402425696 |
449 | Q>K | No |
ClinGen gnomAD |
|
|
rs755545858 CA1841861 |
452 | W>* | No |
ClinGen ExAC gnomAD |
|
|
CA1841860 rs752297899 |
456 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1178177321 CA348315056 |
458 | A>V | No |
ClinGen gnomAD |
|
|
rs1559319486 CA348315051 |
459 | I>T | No |
ClinGen Ensembl |
|
|
CA53744832 rs866760429 |
460 | P>L | No |
ClinGen Ensembl |
|
|
CA348315047 rs1235125075 |
460 | P>T | No |
ClinGen gnomAD |
|
| TCGA novel | 462 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs763515566 CA1841858 |
462 | F>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1841856 rs146995908 |
463 | F>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
COSM1669228 CA1841857 rs146995908 |
463 | F>S | lung central_nervous_system [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ESP ExAC TOPMed gnomAD |
|
rs1559319402 CA348315019 |
464 | S>L | No |
ClinGen Ensembl |
|
|
rs1559319362 CA348315000 |
467 | I>F | No |
ClinGen Ensembl |
|
|
rs1574212571 CA348314996 |
467 | I>M | No |
ClinGen Ensembl |
|
|
CA348314978 rs1290786498 |
469 | T>P | No |
ClinGen TOPMed |
|
|
rs755788907 CA53744823 |
470 | L>F | No |
ClinGen Ensembl |
|
|
CA348314923 rs1172510838 |
472 | C>F | No |
ClinGen TOPMed gnomAD |
|
|
CA1841850 rs200760670 |
473 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 474 | Y>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1841849 rs760659361 |
475 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 477 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs766954729 CA53744805 |
480 | V>L | No |
ClinGen ExAC gnomAD |
|
|
rs766954729 CA1841848 |
480 | V>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 482 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA53744794 rs772282686 |
482 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs772282686 CA1841847 |
482 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA1841846 rs745742104 |
484 | I>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 486 | R>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs770808675 CA1841844 |
492 | C>F | No |
ClinGen ExAC gnomAD |
|
|
rs1158074157 CA348314628 |
493 | R>G | No |
ClinGen gnomAD |
|
|
rs777266735 CA348314610 |
495 | H>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749146036 CA348314613 |
495 | H>N | No |
ClinGen ExAC gnomAD |
|
|
rs567538647 CA1841841 |
495 | H>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA1841842 rs777266735 |
495 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM1185982 CA1841843 rs749146036 |
495 | H>Y | lung [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA348314607 COSM1005727 rs1483244089 |
496 | R>* | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA gnomAD |
|
CA348314605 rs139024940 |
496 | R>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA1841840 rs139024940 |
496 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs780682699 CA1841839 |
499 | R>G | No |
ClinGen ExAC gnomAD |
|
|
CA348314162 rs1410979606 |
500 | V>I | No |
ClinGen TOPMed |
|
|
rs1322229821 CA348314155 |
501 | P>A | No |
ClinGen gnomAD |
|
|
CA348314151 rs1470283204 |
501 | P>L | No |
ClinGen TOPMed |
|
|
rs746574160 CA1841811 |
504 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA348314130 rs1339610981 |
504 | S>N | No |
ClinGen TOPMed gnomAD |
|
|
rs757851206 CA1841809 |
506 | Q>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771891349 CA1841807 |
507 | C>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs754305752 CA1841808 |
507 | C>R | No |
ClinGen ExAC gnomAD |
|
|
CA348314088 rs1395801813 |
510 | L>V | No |
ClinGen gnomAD |
|
|
CA1841805 rs764461296 |
513 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs1366795891 CA348314058 |
514 | H>P | No |
ClinGen TOPMed |
|
|
rs1464336110 CA348314053 |
515 | S>G | No |
ClinGen gnomAD |
|
|
rs1379380747 CA348314051 |
515 | S>N | No |
ClinGen gnomAD |
|
| TCGA novel | 518 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA1841804 rs756457631 |
523 | S>G | No |
ClinGen ExAC gnomAD |
No associated diseases with Q8WV83
1 regional properties for Q8WV83
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | EamA domain | 235 - 315 | IPR000620 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVPPRRHRGA | GRPGVLSSSP | PFRLRSAKFS | GIALEDLRRA | LKTRLQMVCV | FVMNRMNSQN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SGFTQRRRMA | LGIVILLLVD | VIWVASSELT | SYVFTQYNKP | FFSTFAKTSM | FVLYLLGFII |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WKPWRQQCTR | GLRGKHAAFF | ADAEGYFAAC | TTDTTMNSSL | SEPLYVPVKF | HDLPSEKPES |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TNIDTEKTPK | KSRVRFSNIM | EIRQLPSSHA | LEAKLSRMSY | PVKEQESILK | TVGKLTATQV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKISFFFCFV | WFLANLSYQE | ALSDTQVAIV | NILSSTSGLF | TLILAAVFPS | NSGDRFTLSK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLAVILSIGG | VVLVNLAGSE | KPAGRDTVGS | IWSLAGAMLY | AVYIVMIKRK | VDREDKLDIP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| MFFGFVGLFN | LLLLWPGFFL | LHYTGFEDFE | FPNKVVLMCI | IINGLIGTVL | SEFLWLWGCF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LTSSLIGTLA | LSLTIPLSII | ADMCMQKVQF | SWLFFAGAIP | VFFSFFIVTL | LCHYNNWDPV |
| 490 | 500 | 510 | 520 | ||
| MVGIRRIFAF | ICRKHRIQRV | PEDSEQCESL | ISMHSVSQED | GAS |