Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8R314

Entry ID Method Resolution Chain Position Source
AF-Q8R314-F1 Predicted AlphaFoldDB

25 variants for Q8R314

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3390594089 76 L>R No EVA
rs3388495974 143 A>D No EVA
rs3388497299 149 A>E No EVA
rs3388491865 179 E>D No EVA
rs3388496356 179 E>Q No EVA
rs3388491891 180 S>I No EVA
rs3388494265 193 R>H No EVA
rs3388493714 207 S>L No EVA
rs3388493718 223 V>M No EVA
rs212480110 239 T>S No EVA
rs3388497157 241 V>E No EVA
rs3388494230 343 V>I No EVA
rs3390598383 345 I>L No EVA
rs3390538930 346 V>L No EVA
rs1133982977 375 L>Q No EVA
rs1132843477 376 W>C No EVA
rs1132227368 376 W>R No EVA
rs1135257239 380 F>Y No EVA
rs3388494202 419 G>D No EVA
rs3388493733 449 V>M No EVA
rs3388494293 466 F>L No EVA
rs3388494282 478 W>* No EVA
rs3388495416 486 R>S No EVA
rs3388497289 494 R>K No EVA
rs232496026 523 A>T No EVA

No associated diseases with Q8R314

1 regional properties for Q8R314

Type Name Position InterPro Accession
domain EamA domain 236 - 316 IPR000620

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6QL92 SLC35F5 Solute carrier family 35 member F5 Bos taurus (Bovine) PR
Q8WV83 SLC35F5 Solute carrier family 35 member F5 Homo sapiens (Human) PR
10 20 30 40 50 60
MVPPRLHRGA GRPGGLSSLP PFGLGSARFA GIAFEDLREA LATRLQMVYV FIMNRVNSQS
70 80 90 100 110 120
SGFSQRRRMA LGIVILLLVD VIWVASSELT SYVFTQYNKP FFSTFAKTSM FVLYLLGFII
130 140 150 160 170 180
WKPWRQQCTR GFRGKPAAFF ADAEGYFAAC TTDTSMSSSL SEPLYVPVKF HDLPSEKLES
190 200 210 220 230 240
TNIGTEKTPK KSRVRFSNIM EIRQLPSSHA LEAKLSRMSY PTVKDQESIL KTVGKLTATQ
250 260 270 280 290 300
VAKISFFFCF VWFLANLSYQ EALSDTQVAI VNILSSTSGL FTLILAAVFP SNSGDRFTLS
310 320 330 340 350 360
KLLAVILSIG GVVLVNLSGS EKSAGRDTIG SIWSLAGAMF YAVYIVMIKR KVDREDKLDI
370 380 390 400 410 420
PMFFGFVGLF NLLLLWPGFF LLHYTGFEDF EFPNKVVLLC IIINGLIGTV LSEFLWLWGC
430 440 450 460 470 480
FLTSSLIGTL ALSLTIPLSI IADMCMQKVQ FSWLFFAGAI PVFFSFFIVT LLCHYNNWDP
490 500 510 520
VMVGVRRVFA FICRKHRIQR VPEDSEQCES LISMHSVSQE DGAT