Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8W4I5

Entry ID Method Resolution Chain Position Source
AF-Q8W4I5-F1 Predicted AlphaFoldDB

13 variants for Q8W4I5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_8135791_A_G 12 M>T No 1000Genomes
ENSVATH11838070 12 M>V No 1000Genomes
ENSVATH04627000 30 R>C No 1000Genomes
tmp_1_8135644_C_A 61 S>I No 1000Genomes
tmp_1_8135636_C_A 64 A>S No 1000Genomes
tmp_1_8135623_G_A 68 T>M No 1000Genomes
ENSVATH04626996 91 R>* No 1000Genomes
ENSVATH01090715 100 E>D No 1000Genomes
ENSVATH00038761 122 I>V No 1000Genomes
ENSVATH00038760 123 Q>R No 1000Genomes
ENSVATH00038759 141 A>P No 1000Genomes
tmp_1_8135366_C_T 154 A>T No 1000Genomes
ENSVATH04626995 154 A>V No 1000Genomes

No associated diseases with Q8W4I5

1 regional properties for Q8W4I5

Type Name Position InterPro Accession
domain AP2/ERF domain 73 - 140 IPR001471

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

1 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3E958 SHN3 Ethylene-responsive transcription factor SHINE 3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKRIVRISFT DMEATDSSSS EDESPPSSRR RGKKLVKEIV IDHSDPPEVG KTRFKIRIPA
70 80 90 100 110 120
SLLAARNTTA NKKKFRGVRQ RPWGKWAAEI RCGRVKGRPE RIWLGTFETA EEAALAYDNA
130 140 150
AIQLIGPDAP TNFGRPDVDS AVVKKQDSDA SGGASEEVV