Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q3E958

Entry ID Method Resolution Chain Position Source
AF-Q3E958-F1 Predicted AlphaFoldDB

17 variants for Q3E958

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_8820640_G_A 2 V>I No 1000Genomes
ENSVATH07041991 4 S>L No 1000Genomes
ENSVATH14191359 26 L>F No 1000Genomes
ENSVATH00647436 51 V>I No 1000Genomes
tmp_5_8821385_T_C 72 S>P No 1000Genomes
ENSVATH07042015 75 I>V No 1000Genomes
ENSVATH07042017 78 A>T No 1000Genomes
ENSVATH14191362 81 S>F No 1000Genomes
tmp_5_8821534_A_C 121 K>N No 1000Genomes
tmp_5_8821608_G_C 146 G>A No 1000Genomes
ENSVATH11042826 147 G>D No 1000Genomes
ENSVATH07042022 149 I>M No 1000Genomes
ENSVATH07042023 150 E>G No 1000Genomes
ENSVATH07042025 157 R>Q No 1000Genomes
tmp_5_8821657_G_C 162 Q>H No 1000Genomes
ENSVATH00647439 183 S>C No 1000Genomes
ENSVATH07042026 186 I>M No 1000Genomes

No associated diseases with Q3E958

1 regional properties for Q3E958

Type Name Position InterPro Accession
domain AP2/ERF domain 5 - 69 IPR001471

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

1 GO annotations of biological process

Name Definition
ethylene-activated signaling pathway The series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8W4I5 ERF069 Ethylene-responsive transcription factor ERF069 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVHSKKFRGV RQRQWGSWVS EIRHPLLKRR VWLGTFDTAE TAARAYDQAA VLMNGQSAKT
70 80 90 100 110 120
NFPVIKSNGS NSLEINSALR SPKSLSELLN AKLRKNCKDQ TPYLTCLRLD NDSSHIGVWQ
130 140 150 160 170 180
KRAGSKTSPN WVKLVELGDK VNARPGGDIE TNKMKVRNED VQEDDQMAMQ MIEELLNWTC
PGSGSIAQV