Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8W0K2

Entry ID Method Resolution Chain Position Source
AF-Q8W0K2-F1 Predicted AlphaFoldDB

No variants for Q8W0K2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8W0K2

No associated diseases with Q8W0K2

2 regional properties for Q8W0K2

Type Name Position InterPro Accession
repeat Sugar transporter SWEET repeat 10 - 98 IPR004316-1
repeat Sugar transporter SWEET repeat 133 - 215 IPR004316-2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
sugar transmembrane transporter activity Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.

1 GO annotations of biological process

Name Definition
carbohydrate transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A3BWJ9 SWEET7E Putative bidirectional sugar transporter SWEET7e Oryza sativa subsp japonica (Rice) PR
B9G2E6 SWEET7D Putative bidirectional sugar transporter SWEET7d Oryza sativa subsp japonica (Rice) PR
Q8LFH5 SWEET8 Bidirectional sugar transporter SWEET8 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MISPDAARNV VGIIGNVISF GLFLSPVPTF WRICKRKDVE QFKADPYLAT LLNCMLWVFY
70 80 90 100 110 120
GIPIVHPNSI LVVTINGIGL IVEGTYLFIF FLYSPNKKRL RMLAVLGVEL VFMLAVILGV
130 140 150 160 170 180
LLSAHTHKKR SMIVGILCVF FGSIMYFSPL TIMGKVIKTK SVEYMPFFLS LVCFLNGVCW
190 200 210 220 230 240
TAYALIRFDI YVTIPNGLGA IFGAIQLILY ACYYRTTPKK TKAAKDVEMP SVISGPGAAA
250
TASGGSVVSV TVER