Q8W033
PR
Gene name |
ALDH3I1 (ALDH3, At4g34240, F10M10.10) |
Protein name |
Aldehyde dehydrogenase family 3 member I1, chloroplastic |
Names |
AtALDH3, Ath-ALDH3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G34240 |
EC number |
1.2.1.3: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8W033
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8W033-F1 | Predicted | AlphaFoldDB |
53 variants for Q8W033
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_16389809_G_T | 3 | K>N | No | 1000Genomes | |
| ENSVATH00551889 | 4 | L>F | No | 1000Genomes | |
| ENSVATH06822474 | 6 | E>G | No | 1000Genomes | |
| ENSVATH12384988 | 6 | E>Q | No | 1000Genomes | |
| tmp_4_16389822_A_G | 8 | N>D | No | 1000Genomes | |
| ENSVATH06822475 | 14 | C>S | No | 1000Genomes | |
| tmp_4_16389841_G_A | 14 | C>Y | No | 1000Genomes | |
| ENSVATH14335022 | 15 | F>L | No | 1000Genomes | |
| ENSVATH06822476 | 20 | S>C | No | 1000Genomes | |
| ENSVATH06822487 | 28 | T>N | No | 1000Genomes | |
| ENSVATH00551890 | 32 | R>L | No | 1000Genomes | |
| ENSVATH06822488 | 33 | I>L | No | 1000Genomes | |
| tmp_4_16390159_C_G | 36 | R>G | No | 1000Genomes | |
| ENSVATH02956586 | 45 | A>V | No | 1000Genomes | |
| tmp_4_16390446_T_G | 53 | F>L | No | 1000Genomes | |
| ENSVATH02956587 | 71 | S>R | No | 1000Genomes | |
| tmp_4_16390513_G_T | 76 | A>S | No | 1000Genomes | |
| ENSVATH06822493 | 77 | L>F | No | 1000Genomes | |
| ENSVATH06822494 | 80 | D>G | No | 1000Genomes | |
| tmp_4_16390528_G_A | 81 | E>K | No | 1000Genomes | |
| tmp_4_16390548_C_A | 87 | N>K | No | 1000Genomes | |
| tmp_4_16390565_G_A | 93 | S>N | No | 1000Genomes | |
| tmp_4_16390571_A_G | 95 | E>G | No | 1000Genomes | |
| ENSVATH12384993 | 102 | Q>* | No | 1000Genomes | |
| tmp_4_16390646_A_G | 120 | Y>C | No | 1000Genomes | |
| ENSVATH00551892 | 127 | E>D | No | 1000Genomes | |
| ENSVATH02956588 | 138 | T>S | No | 1000Genomes | |
| tmp_4_16390826_A_C | 151 | N>H | No | 1000Genomes | |
| tmp_4_16390974_G_A | 172 | V>I | No | 1000Genomes | |
| tmp_4_16390989_G_A | 177 | G>R | No | 1000Genomes | |
| ENSVATH00551898 | 217 | A>T | No | 1000Genomes | |
| ENSVATH12385045 | 233 | T>I | No | 1000Genomes | |
| ENSVATH12385046 | 253 | D>N | No | 1000Genomes | |
| ENSVATH12385047 | 272 | A>V | No | 1000Genomes | |
| ENSVATH02956591 | 273 | R>I | No | 1000Genomes | |
| tmp_4_16391623_G_T | 300 | A>S | No | 1000Genomes | |
| ENSVATH12385049 | 312 | S>C | No | 1000Genomes | |
| tmp_4_16391698_A_G | 325 | T>A | No | 1000Genomes | |
| tmp_4_16391705_A_G | 327 | D>G | No | 1000Genomes | |
| tmp_4_16391719_T_G | 332 | L>V | No | 1000Genomes | |
| tmp_4_16391924_A_C | 371 | K>T | No | 1000Genomes | |
| tmp_4_16392117_A_G | 407 | M>V | No | 1000Genomes | |
| ENSVATH06822508 | 423 | K>E | No | 1000Genomes | |
| tmp_4_16392177_G_T | 427 | G>C | No | 1000Genomes | |
| ENSVATH00551901 | 435 | P>S | No | 1000Genomes | |
| tmp_4_16392298_C_T | 467 | T>I | No | 1000Genomes | |
| ENSVATH02956596 | 486 | I>L | No | 1000Genomes | |
| tmp_4_16392475_A_G | 499 | S>G | No | 1000Genomes | |
| tmp_4_16392503_G_C | 508 | S>T | No | 1000Genomes | |
| ENSVATH14335067 | 525 | K>R | No | 1000Genomes | |
| tmp_4_16392559_G_C | 527 | V>L | No | 1000Genomes | |
| tmp_4_16392565_A_T | 529 | K>* | No | 1000Genomes | |
| ENSVATH02956597 | 536 | I>M | No | 1000Genomes |
No associated diseases with Q8W033
4 regional properties for Q8W033
Functions
| Description | ||
|---|---|---|
| EC Number | 1.2.1.3 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast envelope | The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3-chloroallyl aldehyde dehydrogenase activity | Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid. |
| aldehyde dehydrogenase (NAD+) activity | Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+. |
| aldehyde dehydrogenase (NADP+) activity | Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+. |
| glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity | Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular aldehyde metabolic process | The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. |
| response to abscisic acid | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. |
| response to water deprivation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P30907 | ALDH3A1 | Aldehyde dehydrogenase, dimeric NADP-preferring | Bos taurus (Bovine) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTKLLEINHI | QTLCFAKGFS | PARLNVATSP | FRISRRGGGG | YCSNACIPYR | LKFTCYATLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AVVKEQASDF | SGKEAALLVD | ELRSNFNSGR | TKSYEWRISQ | LQNIARMIDE | KEKCITEALY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QDLSKPELEA | FLAEISNTKS | SCMLAIKELK | NWMAPETVKT | SVTTFPSSAQ | IVSEPLGVVL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VISAWNFPFL | LSVEPVIGAI | AAGNAVVLKP | SEIAPAASSL | LAKLFSEYLD | NTTIRVIEGG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VPETTALLDQ | KWDKIFFTGG | ARVARIIMAA | AARNLTPVVL | ELGGKCPALV | DSDVNLQVAA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RRIIAGKWAC | NSGQACIGVD | YVITTKDFAS | KLIDALKTEL | ETFFGQNALE | SKDLSRIVNS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FHFKRLESML | KENGVANKIV | HGGRITEDKL | KISPTILLDV | PEASSMMQEE | IFGPLLPIIT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VQKIEDGFQV | IRSKPKPLAA | YLFTNNKELE | KQFVQDVSAG | GITINDTVLH | VTVKDLPFGG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VGESGIGAYH | GKFSYETFSH | KKGVLYRSFS | GDADLRYPPY | TPKKKMVLKA | LLSSNIFAAI |
| LAFFGFSKDS |