P30907

PR
Gene name
ALDH3A1 (ALDH3)
Protein name
Aldehyde dehydrogenase, dimeric NADP-preferring
Names
Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, Corneal 15.8 kDa protein, Corneal protein 54, bCP54, Transparentin
Species
Bos taurus (Bovine)
KEGG Pathway
EC number
1.2.1.5: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

176-239 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P30907

Entry ID Method Resolution Chain Position Source
AF-P30907-F1 Predicted AlphaFoldDB

No variants for P30907

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P30907

No associated diseases with P30907

2 regional properties for P30907

Type Name Position InterPro Accession
domain Aldehyde dehydrogenase domain 1 - 212 IPR015590
conserved_site Aldehyde dehydrogenase, cysteine active site 23 - 34 IPR016160

Functions

Description
EC Number 1.2.1.5 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
aldehyde dehydrogenase (NAD+) activity Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.

2 GO annotations of biological process

Name Definition
cellular aldehyde metabolic process The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8W033 ALDH3I1 Aldehyde dehydrogenase family 3 member I1, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
NPHYVDKDRD LDIACRRIAW GKFMNSGQTC VAPDYILCDP SIQSQVVEKL KKSLKEFYGE
70 80 90 100 110 120
DAKKSRDYGR IINSRHFQRV MGLLEGQKVA YGGTGDATTR YIAPTILTDV DPESPVMQEE
130 140 150 160 170 180
VFGPVLPIMC VRSLEEAIQF ITQREKPLAL YVFSPNDKVI KKMIAETSSG GVTANDVVVH
190 200 210 220 230
ISVHSLPYGG VGDSGMGSYH GRKSFETFSH RRSCLVRPLL NEETLKARYP RARPICPDT