Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8VY21

Entry ID Method Resolution Chain Position Source
AF-Q8VY21-F1 Predicted AlphaFoldDB

16 variants for Q8VY21

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_2_19612748_T_G 7 I>L No 1000Genomes
ENSVATH05737057 9 D>N No 1000Genomes
tmp_2_19612726_A_C 14 L>R No 1000Genomes
tmp_2_19612706_C_T 21 G>R No 1000Genomes
tmp_2_19612682_C_T 29 G>S No 1000Genomes
tmp_2_19612636_A_C 44 V>G No 1000Genomes
ENSVATH14625787 72 D>G No 1000Genomes
tmp_2_19612553_C_T 72 D>N No 1000Genomes
ENSVATH05737053 99 R>K No 1000Genomes
ENSVATH05737052 103 L>V No 1000Genomes
ENSVATH05737051 107 L>F No 1000Genomes
tmp_2_19612298_T_C 128 M>V No 1000Genomes
tmp_2_19612072_T_C 173 N>S No 1000Genomes
tmp_2_19612070_A_T 174 C>S No 1000Genomes
tmp_2_19611899_G_A 205 T>M No 1000Genomes
tmp_2_19611536_G_A 294 S>L No 1000Genomes

No associated diseases with Q8VY21

2 regional properties for Q8VY21

Type Name Position InterPro Accession
domain Tubby, C-terminal 113 - 406 IPR000007
domain F-box domain 52 - 100 IPR001810

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
  • Plastid
  • Nucleus, nucleoplasm
  • Cytoplasm
  • Phospholipase C activity mediates the release from the plasma membrane and the relocation to plastids, cytoplasm and nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5QM27 TULP1 Tubby-like F-box protein 1 Oryza sativa subsp japonica (Rice) PR
Q8LJA9 TULP3 Tubby-like F-box protein 3 Oryza sativa subsp japonica (Rice) PR
Q6Z2G9 TULP5 Tubby-like F-box protein 5 Oryza sativa subsp japonica (Rice) PR
Q68Y48 TULP9 Tubby-like F-box protein 9 Oryza sativa subsp japonica (Rice) PR
Q688Y7 TULP10 Tubby-like F-box protein 10 Oryza sativa subsp japonica (Rice) PR
Q10LG8 TULP6 Tubby-like F-box protein 6 Oryza sativa subsp japonica (Rice) PR
Q0WPY0 TULP6 Tubby-like F-box protein 6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SQU1 TULP9 Tubby-like F-box protein 9 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MSFKSLIQDM RGELGSISRK GFDVRFGYGR SRSQRVVQDT SVPVDAFKQS CWASMPPELL
70 80 90 100 110 120
RDVLMRIEQS EDTWPSRKNV VSCAGVCRNW REIVKEIVRV PELSSKLTFP ISLKQPGPRG
130 140 150 160 170 180
SLVQCYIMRN RSNQTYYLYL GLNQAASNDD GKFLLAAKRF RRPTCTDYII SLNCDDVSRG
190 200 210 220 230 240
SNTYIGKLRS NFLGTKFTVY DAQPTNPGTQ VTRTRSSRLL SLKQVSPRIP SGNYPVAHIS
250 260 270 280 290 300
YELNVLGSRG PRRMQCVMDA IPASAVEPGG TAPTQTELVH SNLDSFPSFS FFRSKSIRAE
310 320 330 340 350 360
SLPSGPSSAA QKEGLLVLKN KAPRWHEQLQ CWCLNFNGRV TVASVKNFQL VAAPENGPAG
370 380 390 400
PEHENVILQF GKVGKDVFTM DYQYPISAFQ AFTICLSSFD TKIACE