Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8VHZ4

Entry ID Method Resolution Chain Position Source
AF-Q8VHZ4-F1 Predicted AlphaFoldDB

No variants for Q8VHZ4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8VHZ4

No associated diseases with Q8VHZ4

No regional properties for Q8VHZ4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8VHZ4

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
inflammatory response to antigenic stimulus An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9UL42 PNMA2 Paraneoplastic antigen Ma2 Homo sapiens (Human) PR
Q9H0W5 CCDC8 Coiled-coil domain-containing protein 8 Homo sapiens (Human) PR
Q8BHK0 Pnma2 Paraneoplastic antigen Ma2 homolog Mus musculus (Mouse) PR
Q8C1C8 Pnma1 Paraneoplastic antigen Ma1 homolog Mus musculus (Mouse) PR
10 20 30 40 50 60
MAMTLLEDWC RGMDVNSQRA LLVWGIPVNC DETEIEETLQ AAMPQVSYRV LGRMFWREEN
70 80 90 100 110 120
AKAALLELTG TVDYSLIPRE MPGKGGLWKV VFKPPTSDAE FLERLHLFLA REGWTVQDVA
130 140 150 160 170 180
RVLGFQNPAP APGPEMPAEM LNYILDNVIQ PLVESIWYKK LTLFSGRDIP GPGEETFDSW
190 200 210 220 230 240
LEHSNEVIEE WQVSDIEKRR RLMESLRGPA ADVIRILKTN NPAITTAECL KALEQVFGSV
250 260 270 280 290 300
ESSRDAQVRF LNTYQNPGEK LSSYVIRLEP LLQKVVDKGA IDKDNVNQAR LEQVIAGANH
310 320 330 340 350
SGALRRQLWL TGATEGPAPN LFQLLVQIRE EEAKEEEEEA EAALLQLGLE GHF