Q8VDN4

PR
Gene name
Ccdc92 (D5Bwg0834e)
Protein name
Coiled-coil domain-containing protein 92
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:215707
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

150-224 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8VDN4

Entry ID Method Resolution Chain Position Source
AF-Q8VDN4-F1 Predicted AlphaFoldDB

11 variants for Q8VDN4

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388793970 24 H>Y No EVA
rs3388791158 26 S>I No EVA
rs3388792777 32 H>Y No EVA
rs33052954 80 A>T No EVA
rs3388786851 83 E>K No EVA
rs3396109235 145 L>RGEVGHSAGALLQLT* No EVA
rs3388793976 168 A>V No EVA
rs3388779443 245 L>F No EVA
rs3388784629 255 S>N No EVA
rs3388779466 260 H>N No EVA
rs3388774466 280 H>L No EVA

No associated diseases with Q8VDN4

1 regional properties for Q8VDN4

Type Name Position InterPro Accession
domain CCDC92/74, N-terminal 7 - 55 IPR039496

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
centriole A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
centrosome A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
nucleoplasm That part of the nuclear content other than the chromosomes or the nucleolus.

1 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.

1 GO annotations of biological process

Name Definition
innate immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q53HC0 CCDC92 Coiled-coil domain-containing protein 92 Homo sapiens (Human) PR
10 20 30 40 50 60
MAATNLENQL HSAQKNLLFL QREHASTLKG LHAEIRRLQQ HCTDLTYELT LKSFELTGDS
70 80 90 100 110 120
SSRTTELKRR CEELEAQLKA KEEENRKLLQ ELEQKNAAIA VLENTVRERE KKYLEELKVK
130 140 150 160 170 180
SHKLSMLSGE LEQRASTVAY LTSQLHAAKK KLLSSSGTSD ASPAGSPALA SYKPTPPKDK
190 200 210 220 230 240
LPETPRRRMK KSLSAPLHPE FEEVYRFGAE SRKLLLREPV DAMPDPTPFL LARESAEVQL
250 260 270 280 290 300
KERPLVIPPI ASDRSATGQH SPARDKPHKT HVGVAHRIHH ATPSQAQPEG EMRAVDQVNA
310
SKVVRKHSGT DRTV