Q8VC52

PR
Gene name
Rbpms2
Protein name
RNA-binding protein with multiple splicing 2
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:71973
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-45 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8VC52

Entry ID Method Resolution Chain Position Source
AF-Q8VC52-F1 Predicted AlphaFoldDB

9 variants for Q8VC52

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3400267027 25 R>H No EVA
rs3389055945 57 K>T No EVA
rs1133614489 75 A>E No EVA
rs1132570564 77 A>E No EVA
rs3389055961 93 Q>L No EVA
rs3389055935 99 F>Y No EVA
rs3389000917 155 Y>H No EVA
rs3389021049 166 T>I No EVA
rs3389061627 177 A>T No EVA

No associated diseases with Q8VC52

2 regional properties for Q8VC52

Type Name Position InterPro Accession
domain RNA recognition motif domain 25 - 102 IPR000504
domain RBPMS2, RNA recognition motif 24 - 99 IPR034787

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
  • Cytoplasm, Stress granule
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
protein homodimerization activity Binding to an identical protein to form a homodimer.

4 GO annotations of biological process

Name Definition
embryonic digestive tract morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
negative regulation of BMP signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
negative regulation of smooth muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
positive regulation of smooth muscle cell proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6ZRY4 RBPMS2 RNA-binding protein with multiple splicing 2 Homo sapiens (Human) PR
10 20 30 40 50 60
MSNLKPDVEH CTGAGTGSPL EEEVRTLFVS GLPVDIKPRE LYLLFRPFKG YEGSLIKLTS
70 80 90 100 110 120
RQPVGFVIFD SRAGAEAAKN ALNGIRFDPE NPQTLRLEFA KANTKMAKSK LIATPNPTSV
130 140 150 160 170 180
HPALGAHLIA RDPYDLMGTA LIPASPEAWA PYPLYTTELT PAISHTTFTY PAATAAAAAA
190 200
ATLHAQVRWY PSSDTTQQGW KYRQFC