Q8S7E1

PR
Gene name
CAO (LLS1)
Protein name
Chlorophyllide a oxygenase, chloroplastic
Names
Chlorophyll a oxygenase, Chlorophyll b synthase
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4349433
EC number
1.14.13.122: With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

95-235 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8S7E1

Entry ID Method Resolution Chain Position Source
AF-Q8S7E1-F1 Predicted AlphaFoldDB

No variants for Q8S7E1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8S7E1

No associated diseases with Q8S7E1

4 regional properties for Q8S7E1

Type Name Position InterPro Accession
domain Pheophorbide a oxygenase 407 - 501 IPR013626
binding_site Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site 261 - 283 IPR015881
domain Rieske [2Fe-2S] iron-sulphur domain 220 - 320 IPR017941
domain Vanillate O-demethylase oxygenase-like, C-terminal catalytic domain 353 - 377 IPR044043

Functions

Description
EC Number 1.14.13.122 With NADH or NADPH as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Plastid, chloroplast membrane; Peripheral membrane protein
  • Plastid, chloroplast thylakoid membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
chloroplast thylakoid membrane The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
chlorophyllide a oxygenase [overall] activity Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.
iron ion binding Binding to an iron (Fe) ion.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
chlorophyll biosynthetic process The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9MBA1 CAO Chlorophyllide a oxygenase, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MTTVASLSLL PHLLIKPSFR CCSRKGVGRY GGIKVYAVLG DDGADYAKNN AWEALFHVDD
70 80 90 100 110 120
PGPRVPIAKG KFLDVNQALE VVRFDIQYCD WRARQDLLTI MVLHNKVVEV LNPLAREFKS
130 140 150 160 170 180
IGTLRKELAE LQEELAKAHN QVHLSETRVS SALDKLAQME TLVNDRLLQD GGSSASTAEC
190 200 210 220 230 240
TSLAPSTSSA SRVVNKKPPR RSLNVSGPVQ PYNPSLKNFW YPVAFSSDLK DDTMVPIDCF
250 260 270 280 290 300
EEQWVIFRGK DGRPGCVMNT CAHRACPLHL GSVNEGRIQC PYHGWEYSTD GKCEKMPSTK
310 320 330 340 350 360
MLNVRIRSLP CFEQEGMVWI WPGNDPPKST IPSLLPPSGF TIHAEIVMEL PVEHGLLLDN
370 380 390 400 410 420
LLDLAHAPFT HTSTFAKGWS VPSLVKFLTP SSGLQGYWDP YPIDMEFRPP CMVLSTIGIS
430 440 450 460 470 480
KPGKLEGKST KQCSTHLHQL HICLPSSRNK TRLLYRMSLD FAPWIKHVPF MHILWSHFAE
490 500 510 520 530 540
KVLNEDLRLV LGQQERMING ANVWNWPVSY DKLGIRYRLW RDAIERGVDR LPFSNQSESG
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