Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8RWG3

Entry ID Method Resolution Chain Position Source
AF-Q8RWG3-F1 Predicted AlphaFoldDB

51 variants for Q8RWG3

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH14442343 3 L>P No 1000Genomes
ENSVATH06325137 10 A>V No 1000Genomes
ENSVATH12788986 22 S>Y No 1000Genomes
tmp_3_20829525_C_A 40 T>N No 1000Genomes
tmp_3_20829531_A_C 42 E>A No 1000Genomes
tmp_3_20829624_C_T 73 P>L No 1000Genomes
ENSVATH00422270 79 A>T No 1000Genomes
ENSVATH06325140 84 K>Q No 1000Genomes
tmp_3_20829662_T_C 86 S>P No 1000Genomes
ENSVATH06325143 91 S>P No 1000Genomes
tmp_3_20829680_G_A 92 E>K No 1000Genomes
ENSVATH02513086 101 S>L No 1000Genomes
ENSVATH12788988 104 E>V No 1000Genomes
ENSVATH02513087 109 P>R No 1000Genomes
ENSVATH02513088 118 S>P No 1000Genomes
ENSVATH06325145 120 P>S No 1000Genomes
ENSVATH06325146 123 V>L No 1000Genomes
ENSVATH02513089 125 K>R No 1000Genomes
tmp_3_20829829_G_T 141 E>D No 1000Genomes
tmp_3_20829839_A_T 145 M>L No 1000Genomes
tmp_3_20829865_G_T 153 W>C No 1000Genomes
tmp_3_20829944_C_A 180 L>I No 1000Genomes
ENSVATH12788989 189 R>I No 1000Genomes
tmp_3_20829977_G_A 191 V>I No 1000Genomes
tmp_3_20829980_G_A 192 E>K No 1000Genomes
tmp_3_20829981_A_T 192 E>V No 1000Genomes
tmp_3_20830044_A_G 213 N>S No 1000Genomes
ENSVATH12788990 217 D>E No 1000Genomes
tmp_3_20830214_C_T 242 P>S No 1000Genomes
tmp_3_20830236_A_T 249 D>V No 1000Genomes
ENSVATH00422271 255 I>L No 1000Genomes
ENSVATH00422275 274 G>A No 1000Genomes
ENSVATH12788994 276 S>L No 1000Genomes
ENSVATH06325149 298 F>L No 1000Genomes
tmp_3_20830699_G_A 300 R>H No 1000Genomes
tmp_3_20830752_A_C 318 S>R No 1000Genomes
ENSVATH06325150 333 M>L No 1000Genomes
ENSVATH14442395 345 G>R No 1000Genomes
tmp_3_20830909_C_A 370 A>E No 1000Genomes
tmp_3_20831032_G_T 411 R>I No 1000Genomes
ENSVATH02513097 499 I>L No 1000Genomes
tmp_3_20831851_G_T 560 A>S No 1000Genomes
ENSVATH02513098 562 R>K No 1000Genomes
ENSVATH12789017 576 S>G No 1000Genomes
ENSVATH14442399 593 V>I No 1000Genomes
ENSVATH00422278 618 I>L No 1000Genomes
ENSVATH06325158 622 V>I No 1000Genomes
ENSVATH06325160 669 S>T No 1000Genomes
tmp_3_20832566_G_A 712 S>N No 1000Genomes
tmp_3_20832616_G_C 729 E>Q No 1000Genomes
ENSVATH00422280 732 T>A No 1000Genomes

No associated diseases with Q8RWG3

1 regional properties for Q8RWG3

Type Name Position InterPro Accession
domain Haem-binding uptake, Tiki superfamily, ChaN 152 - 383 IPR007314

Functions

Description
EC Number
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SIY5 RER5 Protein RETICULATA-RELATED 5, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKLTTNDLFA SQPLFHCPCS SSSRPRRRRF YGLHFPINLT SEKNNSLSIV ALSDSDLPSR
70 80 90 100 110 120
TAFSRRAFLL APPLLVSAAS LFLKPSVSLA SEESSSATVT SPAESAAPPP PPATTTPSPP
130 140 150 160 170 180
PPVNKEETIT SRIYDATAIG EPMAMGKDKK KVWEKLLNAR VVYLGEAEQV PTKDDKELEL
190 200 210 220 230 240
EIVRNLRKRC VESERQISVA LEAFPLDLQD QLNQYMDKRM DGETLKSYVT HWPAQRWQEY
250 260 270 280 290 300
EPLLSYCRDN SVRLIACGTP LKVLRTVQAE GIRGLSKSER KLYTPPAGSG FISGFSSFSR
310 320 330 340 350 360
RSTFDMSLPT QIVPFGPSSY LSAQARVVED HTMSQVILQA VADGGGTGLL LVVTGASHVE
370 380 390 400 410 420
YGSRGTGLPA RISRKFPKKN QVVVLLDPER QFLRREGETP VADFLWYSAA RPCSRNCFDR
430 440 450 460 470 480
AEIARVMNAA GRRRDALPPD IQNGLDLGLV SPEVLQNLFD LEQYPLISEL TQRFQGFRER
490 500 510 520 530 540
LLADPKFLNR LAIEEAISIT TTLIAQYEKR KENFFEEIDY VITDTVRGSV VDFFTVWLPA
550 560 570 580 590 600
PTLSFLSYAD ETTGPDSIDA LRGLLGSIPD NAFQKSLAGR EWNLNLRIAS VIVGGLKLAG
610 620 630 640 650 660
VGVVSSFAAV GASNALNIAR KVIKPELVVA EKPKRSPLLK TAMVYGGFLG TSANLRYQII
670 680 690 700 710 720
AGLIEHRLSD ELSSQPLLVN AISFVVRTLN SYFGTQQWID LARSTGLQTQ KSIPASKEIS
730 740
EALEEPTVEC DTTTEEESID KLNNQ