Q8R2H3

PR
Gene name
Bsnd
Protein name
Barttin
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:192675
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

42-308 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8R2H3

Entry ID Method Resolution Chain Position Source
AF-Q8R2H3-F1 Predicted AlphaFoldDB

No variants for Q8R2H3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8R2H3

No associated diseases with Q8R2H3

No regional properties for Q8R2H3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8R2H3

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
basolateral plasma membrane The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.

2 GO annotations of molecular function

Name Definition
chloride channel activity Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
chloride channel regulator activity Binds to and modulates the activity of a chloride channel.

1 GO annotations of biological process

Name Definition
chloride transport The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8VIM4 Bsnd Barttin Mus musculus (Mouse) PR
10 20 30 40 50 60
MADEKTFRIG FIVLGLFLLS LGTFLMSHDR PQVYGTFYAM GSIMVIGGVL WSMCQCYPKI
70 80 90 100 110 120
TFVPADSDFQ GMLSPKALSL LETGLSEVKS PQPPYVRLWE EAAYDQSLPD FTHIQMKVMG
130 140 150 160 170 180
YSEDPRPLLA PELKTGTSSA KEGEPHSAQT WMEAAVVVHR ELDEKEGEKS RSQSSPPACS
190 200 210 220 230 240
QGSAPLASFH DDLDVGSSEG RSPQPSPPDR DEAHLQVPWA SRGPLDRFGD FALIDDTPIS
250 260 270 280 290 300
EDMGLEGQAQ EEALPSKQPW SLRMKEETVQ AGAEEPEQEE EDLYYGLPDS PGDPLPDKEL
GFEPDVQG