Q8R0A5
Gene name |
Tceal3 |
Protein name |
Transcription elongation factor A protein-like 3 |
Names |
TCEA-like protein 3, Transcription elongation factor S-II protein-like 3 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:594844 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8R0A5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8R0A5-F1 | Predicted | AlphaFoldDB |
17 variants for Q8R0A5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389483460 | 4 | V>I | No | EVA | |
| rs231347882 | 6 | G>D | No | EVA | |
| rs3389572363 | 13 | E>D | No | EVA | |
| rs3412232990 | 14 | K>N | No | EVA | |
| rs3412034116 | 16 | G>A | No | EVA | |
| rs3389533946 | 43 | A>S | No | EVA | |
| rs29264668 | 44 | P>A | No | EVA | |
| rs3389567779 | 45 | R>H | No | EVA | |
| rs3389569919 | 58 | Q>R | No | EVA | |
| rs3389577020 | 67 | K>M | No | EVA | |
| rs3389526289 | 129 | Q>E | No | EVA | |
| rs3389576257 | 129 | Q>L | No | EVA | |
| rs583325812 | 143 | A>T | No | EVA | |
| rs13459342 | 170 | D>Y | No | EVA | |
| rs3389574144 | 171 | A>V | No | EVA | |
| rs3389576952 | 191 | Q>H | No | EVA | |
| rs3412034108 | 201 | L>K | No | EVA |
No associated diseases with Q8R0A5
1 regional properties for Q8R0A5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | THADA/TRM732, DUF2428 | 948 - 1248 | IPR019442 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| WW domain binding | Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2KIJ9 | TCEAL1 | Transcription elongation factor A protein-like 1 | Bos taurus (Bovine) | PR |
| Q15170 | TCEAL1 | Transcription elongation factor A protein-like 1 | Homo sapiens (Human) | PR |
| Q921P9 | Tceal1 | Transcription elongation factor A protein-like 1 | Mus musculus (Mouse) | PR |
| Q5PPP3 | Tceal1 | Transcription elongation factor A protein-like 1 | Rattus norvegicus (Rat) | PR |
| A2D671 | TCEAL1 | Transcription elongation factor A protein-like 1 | Macaca mulatta (Rhesus macaque) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEVRGENEG | KLEKEGKPED | EVEPEDEEKS | DEDEKPDKKA | KPAPRQGKPE | EEAKPDEQGQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DEGKPEKQGK | SDGEGKRQGE | SKPDSQAKSA | SEARAAEKRP | AEDYVPRKAK | RKTDRGTDDS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PKNSQEDLQD | RHVSSEEMMR | ECADMTRAQE | ELRKRQKMGG | FHWVPRDAQD | ALVPRGPRGV |
| 190 | |||||
| RGVRGGGGRS | QRGLHDIPYL |