Q8LFR2
Gene name |
DREB2C (ERF048, At2g40340, T07M07.24, T3G21.11) |
Protein name |
Dehydration-responsive element-binding protein 2C |
Names |
Protein DREB2C |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G40340 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8LFR2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8LFR2-F1 | Predicted | AlphaFoldDB |
29 variants for Q8LFR2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01972853 | 18 | V>I | No | 1000Genomes | |
| ENSVATH00267365 | 32 | I>V | No | 1000Genomes | |
| ENSVATH05690488 | 33 | E>G | No | 1000Genomes | |
| ENSVATH05690487 | 35 | E>D | No | 1000Genomes | |
| tmp_2_16849575_T_A | 39 | D>V | No | 1000Genomes | |
| tmp_2_16849573_C_A | 40 | G>C | No | 1000Genomes | |
| ENSVATH14601598 | 41 | G>A | No | 1000Genomes | |
| tmp_2_16849557_G_A | 45 | S>L | No | 1000Genomes | |
| ENSVATH13594431 | 66 | E>Q | No | 1000Genomes | |
| ENSVATH05690486 | 70 | C>Y | No | 1000Genomes | |
| tmp_2_16849420_C_T | 91 | D>N | No | 1000Genomes | |
| tmp_2_16849386_G_C | 102 | S>C | No | 1000Genomes | |
| ENSVATH00267363 | 113 | E>K | No | 1000Genomes | |
| tmp_2_16849315_T_G | 126 | N>H | No | 1000Genomes | |
| tmp_2_16849243_A_G | 150 | F>L | No | 1000Genomes | |
| ENSVATH14601597 | 175 | D>V | No | 1000Genomes | |
| tmp_2_16849159_C_T | 178 | D>N | No | 1000Genomes | |
| tmp_2_16849048_A_C | 215 | S>A | No | 1000Genomes | |
| ENSVATH00267362 | 218 | E>K | No | 1000Genomes | |
| tmp_2_16848960_A_G | 244 | I>T | No | 1000Genomes | |
| tmp_2_16848882_G_C | 270 | P>R | No | 1000Genomes | |
| ENSVATH01972851 | 272 | F>I | No | 1000Genomes | |
| tmp_2_16848864_G_T | 276 | T>K | No | 1000Genomes | |
| tmp_2_16848853_T_A | 280 | N>Y | No | 1000Genomes | |
| ENSVATH05690482 | 289 | P>L | No | 1000Genomes | |
| ENSVATH14601596 | 298 | D>E | No | 1000Genomes | |
| tmp_2_16848781_C_A | 304 | V>L | No | 1000Genomes | |
| tmp_2_16848736_G_T | 319 | R>S | No | 1000Genomes | |
| ENSVATH05690480 | 336 | D>N | No | 1000Genomes |
No associated diseases with Q8LFR2
14 regional properties for Q8LFR2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | C2 domain | 1071 - 1194 | IPR000008 |
| domain | Phosphatidylinositol-specific phospholipase C, X domain | 320 - 465 | IPR000909 |
| domain | SH2 domain | 548 - 657 | IPR000980-1 |
| domain | SH2 domain | 666 - 756 | IPR000980-2 |
| domain | SH3 domain | 791 - 851 | IPR001452 |
| domain | Phospholipase C, phosphatidylinositol-specific, Y domain | 953 - 1070 | IPR001711 |
| domain | Pleckstrin homology domain | 27 - 144 | IPR001849-1 |
| domain | Pleckstrin homology domain | 489 - 680 | IPR001849-2 |
| domain | Pleckstrin homology domain | 804 - 933 | IPR001849-3 |
| domain | EF-hand domain | 152 - 187 | IPR002048 |
| binding_site | EF-Hand 1, calcium-binding site | 165 - 177 | IPR018247 |
| domain | PLC-gamma, C-terminal SH2 domain | 663 - 765 | IPR035023 |
| domain | PLC-gamma, N-terminal SH2 domain | 545 - 649 | IPR035024 |
| domain | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain | 791 - 850 | IPR035724 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| abscisic acid-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription. |
| heat acclimation | Any process that increases heat tolerance of an organism in response to high temperatures. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| response to abscisic acid | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPSEIVDRKR | KSRGTRDVAE | ILRQWREYNE | QIEAESCIDG | GGPKSIRKPP | PKGSRKGCMK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GKGGPENGIC | DYRGVRQRRW | GKWVAEIREP | DGGARLWLGT | FSSSYEAALA | YDEAAKAIYG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QSARLNLPEI | TNRSSSTAAT | ATVSGSVTAF | SDESEVCARE | DTNASSGFGQ | VKLEDCSDEY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLLDSSQCIK | EELKGKEEVR | EEHNLAVGFG | IGQDSKRETL | DAWLMGNGNE | QEPLEFGVDE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TFDINELLGI | LNDNNVSGQE | TMQYQVDRHP | NFSYQTQFPN | SNLLGSLNPM | EIAQPGVDYG |
| 310 | 320 | 330 | 340 | ||
| CPYVQPSDME | NYGIDLDHRR | FNDLDIQDLD | FGGDKDVHGS | T |