O80917
Gene name |
DREB2E (DREB19) |
Protein name |
Dehydration-responsive element-binding protein 2E |
Names |
Protein DREB2E, Dehydration response element-binding protein 19 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G38340 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O80917
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O80917-F1 | Predicted | AlphaFoldDB |
20 variants for O80917
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_16068166_T_G | 6 | N>H | No | 1000Genomes | |
| ENSVATH13572446 | 14 | A>P | No | 1000Genomes | |
| ENSVATH01964814 | 18 | S>P | No | 1000Genomes | |
| ENSVATH00264569 | 19 | S>L | No | 1000Genomes | |
| tmp_2_16068127_A_G | 19 | S>P | No | 1000Genomes | |
| tmp_2_16068123_C_T | 20 | R>K | No | 1000Genomes | |
| ENSVATH05677800 | 21 | R>K | No | 1000Genomes | |
| tmp_2_16068096_A_C | 29 | V>G | No | 1000Genomes | |
| tmp_2_16068082_G_A | 34 | Q>* | No | 1000Genomes | |
| tmp_2_16068057_G_C | 42 | A>G | No | 1000Genomes | |
| ENSVATH00264568 | 92 | R>H | No | 1000Genomes | |
| tmp_2_16067800_A_T | 128 | Y>N | No | 1000Genomes | |
| tmp_2_16067788_T_A | 132 | N>Y | No | 1000Genomes | |
| ENSVATH05677798 | 140 | G>E | No | 1000Genomes | |
| ENSVATH01964813 | 143 | K>T | No | 1000Genomes | |
| tmp_2_16067701_C_T | 161 | G>S | No | 1000Genomes | |
| ENSVATH00264566 | 170 | G>E | No | 1000Genomes | |
| tmp_2_16067666_G_T | 172 | D>E | No | 1000Genomes | |
| tmp_2_16067538_A_G | 215 | L>S | No | 1000Genomes | |
| ENSVATH01964812 | 231 | Q>L | No | 1000Genomes |
No associated diseases with O80917
8 regional properties for O80917
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SH3 domain | 8 - 69 | IPR001452 |
| domain | Dedicator of cytokinesis protein 2, DHR2 domain | 1200 - 1620 | IPR026799 |
| domain | C2 DOCK-type domain | 419 - 615 | IPR027007 |
| domain | DOCKER domain | 1211 - 1622 | IPR027357 |
| domain | Dedicator of cytokinesis, N-terminal domain | 72 - 414 | IPR032376 |
| domain | DOCKER, Lobe A | 1205 - 1334 | IPR046769 |
| domain | DOCKER, Lobe B | 1395 - 1474 | IPR046770 |
| domain | DOCKER, Lobe C | 1516 - 1615 | IPR046773 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| abscisic acid-activated signaling pathway | The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription. |
| cellular response to heat | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. |
| positive regulation of DNA-templated transcription | Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
| response to salt stress | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. |
| response to water deprivation | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKEDNGSKQ | SSSASVVSSR | RRRRVVEPVE | ATLQRWEEEG | LARARRVQAK | GSKKGCMRGK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GGPENPVCRF | RGVRQRVWGK | WVAEIREPVS | HRGANSSRSK | RLWLGTFATA | AEAALAYDRA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASVMYGPYAR | LNFPEDLGGG | RKKDEEAESS | GGYWLETNKA | GNGVIETEGG | KDYVVYNEDA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IELGHDKTQN | PMTDNEIVNP | AVKSEEGYSY | DRFKLDNGLL | YNEPQSSSYH | QGGGFDSYFE |
| YFRF |