Q8LDS3
Gene name |
RTNLB18 (At4g28430, F20O9.110) |
Protein name |
Reticulon-like protein B18 |
Names |
AtRTNLB18 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G28430 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8LDS3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8LDS3-F1 | Predicted | AlphaFoldDB |
51 variants for Q8LDS3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14305945 | 2 | D>E | No | 1000Genomes | |
| ENSVATH14305924 | 2 | D>H | No | 1000Genomes | |
| ENSVATH06790500 | 3 | S>T | No | 1000Genomes | |
| tmp_4_14057876_C_T | 11 | R>C | No | 1000Genomes | |
| tmp_4_14057880_C_T | 12 | S>L | No | 1000Genomes | |
| tmp_4_14057901_G_A | 19 | R>H | No | 1000Genomes | |
| ENSVATH12276232 | 21 | A>S | No | 1000Genomes | |
| ENSVATH02934942 | 22 | R>Q | No | 1000Genomes | |
| ENSVATH06790502 | 28 | V>I | No | 1000Genomes | |
| ENSVATH06790503 | 30 | S>F | No | 1000Genomes | |
| tmp_4_14057933_T_C | 30 | S>P | No | 1000Genomes | |
| ENSVATH06790504 | 31 | H>Q | No | 1000Genomes | |
| ENSVATH00542686 | 40 | L>S | No | 1000Genomes | |
| ENSVATH06790505 | 50 | Y>F | No | 1000Genomes | |
| ENSVATH06790507 | 112 | A>S | No | 1000Genomes | |
| tmp_4_14058213_G_A | 123 | R>K | No | 1000Genomes | |
| ENSVATH12276233 | 130 | V>L | No | 1000Genomes | |
| ENSVATH12276234 | 135 | N>K | No | 1000Genomes | |
| ENSVATH06790509 | 140 | V>I | No | 1000Genomes | |
| ENSVATH02934945 | 149 | N>K | No | 1000Genomes | |
| ENSVATH02934946 | 160 | K>N | No | 1000Genomes | |
| ENSVATH00542689 | 181 | Q>K | No | 1000Genomes | |
| ENSVATH06790512 | 199 | I>F | No | 1000Genomes | |
| tmp_4_14058556_T_G | 211 | F>V | No | 1000Genomes | |
| ENSVATH06790514 | 225 | A>T | No | 1000Genomes | |
| tmp_4_14058738_C_T | 241 | L>F | No | 1000Genomes | |
| tmp_4_14058750_G_T | 245 | G>W | No | 1000Genomes | |
| ENSVATH02934949 | 262 | R>W | No | 1000Genomes | |
| tmp_4_14058905_G_C | 269 | E>Q | No | 1000Genomes | |
| tmp_4_14058911_G_T | 271 | D>Y | No | 1000Genomes | |
| ENSVATH14305947 | 310 | M>L | No | 1000Genomes | |
| ENSVATH00542690 | 317 | L>P | No | 1000Genomes | |
| ENSVATH02934950 | 327 | G>C | No | 1000Genomes | |
| ENSVATH02934950 | 327 | G>S | No | 1000Genomes | |
| ENSVATH12276267 | 344 | Q>H | No | 1000Genomes | |
| ENSVATH12276268 | 347 | Q>H | No | 1000Genomes | |
| ENSVATH00542693 | 348 | K>T | No | 1000Genomes | |
| ENSVATH12276269 | 351 | C>R | No | 1000Genomes | |
| ENSVATH14305948 | 355 | R>G | No | 1000Genomes | |
| tmp_4_14059479_G_A | 361 | G>R | No | 1000Genomes | |
| ENSVATH12276270 | 385 | T>A | No | 1000Genomes | |
| ENSVATH06790520 | 399 | Y>H | No | 1000Genomes | |
| ENSVATH02934952 | 401 | R>L | No | 1000Genomes | |
| ENSVATH06790521 | 402 | Q>H | No | 1000Genomes | |
| ENSVATH06790522 | 405 | Q>H | No | 1000Genomes | |
| ENSVATH12276271 | 416 | Q>E | No | 1000Genomes | |
| ENSVATH00542694 | 426 | K>E | No | 1000Genomes | |
| ENSVATH06790523 | 432 | S>L | No | 1000Genomes | |
| ENSVATH12276272 | 441 | E>K | No | 1000Genomes | |
| ENSVATH12276273 | 446 | L>V | No | 1000Genomes | |
| ENSVATH14305949 | 450 | T>N | No | 1000Genomes |
No associated diseases with Q8LDS3
1 regional properties for Q8LDS3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Reticulon | 195 - 355 | IPR003388 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q56X72 | RTNLB21 | Reticulon-like protein B21 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSTTTPPSL | RSNTRSALRL | ARNNKTLVKS | HIPSLDLVLL | SPKNNNGTPY | PSPVSLSSPS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SPVTLREILL | LSPSPLRKSR | TRLSNRFDME | AAEAAVTARR | SKTKGGQNGL | LASPSPRNFR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RSRLRSEAMV | DTKENTEPIV | VVTDEKKQNQ | RKQKKLGRSK | KEKHSSVPLL | ASPSPSSDQP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QDVCQGDLER | IRENISDLIM | WRDVAKSTLW | FGFGCICFLS | TCFAAKGFNF | SVFSAISYLG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLFLGVSFLS | NTLRQRVTEE | ARRELKLSED | DVLRIARRML | PITNLAISKT | SELFSGEPAM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TLKVAPFVLM | GAEYGYLITL | WRLCAFGFFL | SFTIPKLYSC | YASQLNQKVE | CAQRRFVEAW |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GVCTHKKFVA | GSAVTAFWNL | TSLKTRFIAV | FIIVVVIRYR | RQNLQLDSED | EEEKKQQEKT |
| 430 | 440 | 450 | |||
| HPEQQKSPED | KSTSPRSAEE | EQALVLVAET | KAPKKLY |