Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q56X72

Entry ID Method Resolution Chain Position Source
AF-Q56X72-F1 Predicted AlphaFoldDB

42 variants for Q56X72

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_23477419_A_C 2 T>P No 1000Genomes
ENSVATH12836730 20 S>A No 1000Genomes
tmp_5_23477498_C_T 28 S>F No 1000Genomes
ENSVATH07443509 34 I>S No 1000Genomes
tmp_5_23477573_C_A 53 T>K No 1000Genomes
tmp_5_23477600_C_T 62 S>L No 1000Genomes
ENSVATH07443510 80 D>N No 1000Genomes
ENSVATH03446681 83 T>S No 1000Genomes
ENSVATH00740120 98 E>D No 1000Genomes
ENSVATH03446682 101 E>D No 1000Genomes
tmp_5_23477725_G_A 104 V>I No 1000Genomes
ENSVATH03446683 116 E>K No 1000Genomes
ENSVATH03446684 139 E>D No 1000Genomes
ENSVATH07443511 140 E>K No 1000Genomes
ENSVATH07443512 141 E>K No 1000Genomes
tmp_5_23477858_A_G 148 K>R No 1000Genomes
ENSVATH00740121 155 I>M No 1000Genomes
ENSVATH07443514 164 G>A No 1000Genomes
tmp_5_23477911_G_T 166 V>F No 1000Genomes
tmp_5_23477925_G_T 170 K>N No 1000Genomes
tmp_5_23477926_T_A 171 F>I No 1000Genomes
ENSVATH03446688 179 S>A No 1000Genomes
tmp_5_23477951_C_A 179 S>Y No 1000Genomes
tmp_5_23477975_A_T 187 K>I No 1000Genomes
ENSVATH00740122 188 I>V No 1000Genomes
ENSVATH07443515 190 P>S No 1000Genomes
tmp_5_23477986_C_T 191 P>S No 1000Genomes
tmp_5_23477995_A_C 194 K>Q No 1000Genomes
tmp_5_23478026_C_G 204 P>R No 1000Genomes
ENSVATH07443516 227 L>M No 1000Genomes
tmp_5_23478317_G_T,A 237 R>K No 1000Genomes
tmp_5_23478317_G_T,A 237 R>M No 1000Genomes
tmp_5_23478552_C_T 286 S>L No 1000Genomes
ENSVATH12836768 294 E>V No 1000Genomes
tmp_5_23478713_A_G 311 M>V No 1000Genomes
tmp_5_23478935_G_T 357 W>C No 1000Genomes
ENSVATH14638605 380 H>P No 1000Genomes
ENSVATH12836773 386 N>S No 1000Genomes
ENSVATH14638606 426 A>V No 1000Genomes
ENSVATH12836775 449 D>V No 1000Genomes
ENSVATH14638607 450 D>H No 1000Genomes
ENSVATH12836776 475 P>H No 1000Genomes

No associated diseases with Q56X72

1 regional properties for Q56X72

Type Name Position InterPro Accession
domain Reticulon 230 - 384 IPR003388

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8LDS3 RTNLB18 Reticulon-like protein B18 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MTPRRSLSSS DSNDKSPSVS VVAKKARSES VEGIEKKTTP GRVKKIRSEV CTTIVKAGEF
70 80 90 100 110 120
DSVALRKVNS LPSPNSEKSD TKTEQEVTII ENSKIPEEVK EFGVCQEMIV SAKSNENEQI
130 140 150 160 170 180
DNGDQEIGDQ DDYEEDGDEE EEREVEKKSV DVKEINVAKE NRVGGVEIKK FSQFQNRTSP
190 200 210 220 230 240
SPSSVRKISP PVIKRATSVY SAPPNSTSST DRFAEQEDNF THSQSKLQSL VDLVMWRDVS
250 260 270 280 290 300
RSTLVFGFGT FLIISSSYAN DLNFSFISVV AYMGLIYLGL MFVLKSLIHR GMVEEERHKV
310 320 330 340 350 360
VGVREEDVKR MLRLIMPYLN ESLHQLRALF SGDPSTTLKM GVVLFVLARC GSSITLWNLA
370 380 390 400 410 420
KFGFLGAFTI PKIFISYSTH FSAYGNFWMR RFRDAWESCN HKKAVALALF TLVWNLSSVT
430 440 450 460 470 480
ARVWAAFMLL VAFRYYQHKM IWTTDQADDD EDDNEEEEAE EEKEQVPPKH KRAPPHMMMP
NKLKKIS