Q8L8Q7
PR
Gene name |
COBL2 (At3g29810, K17E7.7;, COBL3, At1gXXXXX, F21N10.4) |
Protein name |
COBRA-like protein 2 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G29810 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8L8Q7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8L8Q7-F1 | Predicted | AlphaFoldDB |
40 variants for Q8L8Q7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH11345969 | 2 | N>S | No | 1000Genomes | |
| ENSVATH02269643 | 4 | L>F | No | 1000Genomes | |
| ENSVATH02269643 | 4 | L>V | No | 1000Genomes | |
| ENSVATH14104165 | 6 | S>T | No | 1000Genomes | |
| ENSVATH06001573 | 8 | F>L | No | 1000Genomes | |
| ENSVATH06001574 | 15 | L>F | No | 1000Genomes | |
| ENSVATH08005767 | 23 | F>L | No | 1000Genomes | |
| tmp_3_11728572_T_A | 33 | D>E | No | 1000Genomes | |
| ENSVATH11346006 | 45 | M>T | No | 1000Genomes | |
| tmp_3_11728615_A_G | 48 | T>A | No | 1000Genomes | |
| tmp_3_11728751_G_C | 55 | V>L | No | 1000Genomes | |
| ENSVATH02269667 | 61 | F>Y | No | 1000Genomes | |
| ENSVATH06001589 | 69 | A>P | No | 1000Genomes | |
| tmp_3_11728817_A_T | 77 | S>C | No | 1000Genomes | |
| ENSVATH02269669 | 77 | S>I | No | 1000Genomes | |
| ENSVATH02269669 | 77 | S>N | No | 1000Genomes | |
| ENSVATH06001591 | 79 | M>I | No | 1000Genomes | |
| ENSVATH11346040 | 86 | S>G | No | 1000Genomes | |
| tmp_3_11729022_C_T | 145 | A>V | No | 1000Genomes | |
| tmp_3_11729036_T_A | 150 | S>T | No | 1000Genomes | |
| tmp_3_11729060_T_G | 158 | S>A | No | 1000Genomes | |
| ENSVATH02269677 | 162 | N>K | No | 1000Genomes | |
| ENSVATH14104168 | 175 | A>V | No | 1000Genomes | |
| tmp_3_11729150_G_A | 188 | V>I | No | 1000Genomes | |
| tmp_3_11729180_A_G | 198 | K>E | No | 1000Genomes | |
| ENSVATH11346044 | 220 | R>W | No | 1000Genomes | |
| tmp_3_11729350_G_A | 227 | V>I | No | 1000Genomes | |
| ENSVATH00368135 | 249 | N>H | No | 1000Genomes | |
| tmp_3_11729419_A_C | 250 | S>R | No | 1000Genomes | |
| ENSVATH02269711 | 262 | A>V | No | 1000Genomes | |
| tmp_3_11729544_C_T | 266 | P>L | No | 1000Genomes | |
| ENSVATH00368138 | 332 | K>Q | No | 1000Genomes | |
| ENSVATH02269730 | 345 | L>S | No | 1000Genomes | |
| ENSVATH02269729 | 345 | L>V | No | 1000Genomes | |
| ENSVATH02269735 | 364 | S>R | No | 1000Genomes | |
| ENSVATH02269740 | 379 | Q>E | No | 1000Genomes | |
| ENSVATH14104241 | 431 | L>V | No | 1000Genomes | |
| tmp_3_11730155_G_T | 441 | M>I | No | 1000Genomes | |
| ENSVATH14104244 | 441 | M>K | No | 1000Genomes | |
| ENSVATH11346166 | 441 | M>L | No | 1000Genomes |
No associated diseases with Q8L8Q7
No regional properties for Q8L8Q7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8L8Q7 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchored component of membrane | The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. |
| anchored component of plasma membrane | The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi medial cisterna | The middle Golgi cisterna (or cisternae). |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| cellulose microfibril organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall. |
| mucilage biosynthetic process involved in seed coat development | The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development. |
| plant-type cell wall biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana. |
| plant-type cell wall cellulose biosynthetic process | The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall. |
| plant-type cell wall organization | A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana. |
| seed coat development | The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure. |
| seed development | The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9LFW3 | COBL4 | COBRA-like protein 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNILFSRFSF | LLLFLCSWTS | FTFTTTEAYD | ALDPYGNITI | KWDIMSWTGD | GYVAVVTIFN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FQQYRHIEAP | GWQLGWSWMK | KEVIWSMVGG | QATEQGDCSK | FKGNIPHCCK | KTPAIVDLLP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GTPYNQQISN | CCRGGVISAW | AQDPATAISS | FQISVGQSGT | TNTTVRAPRN | ITLKAPGPGY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TCGPAKLVKP | SRFISADKRR | KTQSLLTWNI | TCTYSQFLAR | KTPTCCVSLS | AFYNETIVPC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PTCSCGCQNS | SQAGTCVDPK | IASVVPALGK | NNLEPLLQCT | QHMCPIRVHW | HVKTSYKEYW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RVKVAITNFN | YNMNYSQWNL | VVQHPNFDNL | TKLFSFNYKP | LNPYLNINDT | AMLWGIKFYN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DFLSQAGPVG | NVQSELLFQK | NPLEFTFEKG | WAFPRRIYFN | GDNCVMPPPD | SYPWLPNASP |
| 430 | 440 | ||||
| NIATSPFVIL | LITFLSVLIL | M |