Q8K2Y7

PR
Gene name
Mrpl47
Protein name
39S ribosomal protein L47, mitochondrial
Names
L47mt, MRP-L47
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:74600
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

198-252 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8K2Y7

Entry ID Method Resolution Chain Position Source
AF-Q8K2Y7-F1 Predicted AlphaFoldDB

28 variants for Q8K2Y7

Variant ID(s) Position Change Description Diseaes Association Provenance
rs1132823557 3 A>V No EVA
rs1133954844 7 V>L No EVA
rs1133774233 11 R>K No EVA
rs230390437 15 A>T No EVA
rs3388627093 56 L>I No EVA
rs3388626835 64 K>E No EVA
rs3392863286 78 E>G No EVA
rs3392675224 95 K>I No EVA
rs3388628116 96 S>G No EVA
rs3388625924 102 K>M No EVA
rs3388627053 119 Q>H No EVA
rs3388628847 139 D>E No EVA
rs3388621072 142 D>G No EVA
rs6329218 144 V>L No EVA
rs3388616912 150 E>K No EVA
rs3388628863 154 A>T No EVA
rs1134046275 165 P>S No EVA
rs3388616983 180 W>* No EVA
rs3388629592 184 K>M No EVA
rs29839736 188 I>L No EVA
rs3388622517 195 R>K No EVA
rs3388609349 208 D>N No EVA
rs3388622552 210 F>I No EVA
rs234847714 223 A>T No EVA
rs3388620049 232 K>T No EVA
rs223289806 237 H>Q No EVA
rs254727239 251 S>T No EVA
rs241116189 252 V>A No EVA

No associated diseases with Q8K2Y7

No regional properties for Q8K2Y7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8K2Y7

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P36517 MRPL4 54S ribosomal protein L4, mitochondrial Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q08DT6 MRPL47 39S ribosomal protein L47, mitochondrial Bos taurus (Bovine) PR
Q9HD33 MRPL47 39S ribosomal protein L47, mitochondrial Homo sapiens (Human) PR
10 20 30 40 50 60
MAATSLVGIC RRASAFLKAA CSLVNPKDAA HSGCRSSLSL LHKNTPHVTS FLQCKLLHTT
70 80 90 100 110 120
LSRKGLEEFF DDPKNWGEEK VKSGASWTCQ QLRNKSNEDL HKLWYVLLKE RNMLLTLEQE
130 140 150 160 170 180
AKRQRLPMPS PERLEKVVDS MDNVDKVVQE REDALRLLQT GQEKPRPGAW RRDIFGRIVW
190 200 210 220 230 240
HKFKQWPIPW YLNKRYNRRR FFAMPYVDRF IRLRIEKHAR IEARKRSLQK KKEKILHAKF
250
PHLSQERKSS SV