AiPD: Autoinhibited Protein Database

Gene name	CFDP1
Protein name	Craniofacial development protein 1
Names	Bucentaur, h-type BCNT protein
Species	Bos taurus (Bovine)
KEGG Pathway	bta:281682
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-258 (Predicted disordered autoinhibitory region) PR

1-258 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8HXY9-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs433170244	10	S>P	No	EVA
rs469264245	11	T>P	No	EVA
rs480792916	17	D>A	No	EVA
rs450910724	17	D>H	No	EVA
rs450910724	17	D>N	No	EVA
rs468342277	18	Y>S	No	EVA
rs446668243	19	V>G	No	EVA
rs458053177	21	S>A	No	EVA
rs439177614	21	S>W	No	EVA
rs432566722	26	S>R	No	EVA
rs465622789	27	E>D	No	EVA
rs467720753	28	D>E	No	EVA
rs438330563	28	D>G	No	EVA
rs456766151	28	D>H	No	EVA
rs478876805	35	K>E	No	EVA
rs466923959	60	A>G	No	EVA
rs722158623	78	N>S	No	EVA
rs211330260	86	S>G	No	EVA
rs475862298	168	D>V	No	EVA
rs457447143	170	A>S	No	EVA
rs435727936	170	A>V	No	EVA
rs468374131	171	G>C	No	EVA
rs446697718	171	G>V	No	EVA
rs434632423	172	E>*	No	EVA
rs434632423	172	E>K	No	EVA
rs464477756	173	E>K	No	EVA
rs445612540	174	V>A	No	EVA
rs445612540	174	V>G	No	EVA
rs481876782	175	R>G	No	EVA
rs456081978	183	T>I	No	EVA
rs436276099	252	E>G	No	EVA
rs446678956	271	E>K	No	EVA

Type	Name	Position	InterPro Accession
domain	Cadherin, Y-type LIR-motif	843 - 902	IPR000233
domain	Cadherin-like	160 - 267	IPR002126-1
domain	Cadherin-like	267 - 393	IPR002126-2
domain	Cadherin-like	383 - 497	IPR002126-3
domain	Cadherin-like	498 - 605	IPR002126-4
domain	Cadherin-like	604 - 710	IPR002126-5
domain	Cadherin prodomain	31 - 123	IPR014868
conserved_site	Cadherin conserved site	370 - 380	IPR020894-1
conserved_site	Cadherin conserved site	593 - 603	IPR020894-2

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Swr1 complex	A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.

Name	Definition
No GO annotations for molecular function

Name	Definition
cell adhesion	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
chromatin remodeling	A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
fibroblast apoptotic process	Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
negative regulation of fibroblast apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.
regulation of cell population proliferation	Any process that modulates the frequency, rate or extent of cell proliferation.
regulation of cell shape	Any process that modulates the surface configuration of a cell.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9UEE9	CFDP1	Craniofacial development protein 1	Homo sapiens (Human)	PR
O88271	Cfdp1	Craniofacial development protein 1	Mus musculus (Mouse)	PR
Q75UQ2	Cfdp1	Craniofacial development protein 1	Rattus norvegicus (Rat)	PR