Q75UQ2
Gene name |
Cfdp1 (Bcnt) |
Protein name |
Craniofacial development protein 1 |
Names |
Bucentaur |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:292027 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q75UQ2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q75UQ2-F1 | Predicted | AlphaFoldDB |
1 variants for Q75UQ2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3323427772 | 217 | T>S | No | EVA |
No associated diseases with Q75UQ2
1 regional properties for Q75UQ2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | BCNT-C domain | 214 - 295 | IPR011421 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| kinetochore | A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| Swr1 complex | A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell adhesion | The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. |
| chromatin remodeling | A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. |
| fibroblast apoptotic process | Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. |
| negative regulation of fibroblast apoptotic process | Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. |
| regulation of cell population proliferation | Any process that modulates the frequency, rate or extent of cell proliferation. |
| regulation of cell shape | Any process that modulates the surface configuration of a cell. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEFDSEDFS | TSDEDEDYVP | SGGEYSEDDV | NELVKEDEVD | GEEQAEKTKG | KRRKAQSIPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RKRKQSGLLL | DEEEDGEEDS | GGSSREEDEE | EQEGGLGSET | SRKKKEDELW | ASFLNDVGTK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SKAASSSQVK | VAEETEETSS | SKPLVKADEL | EKPKESEKVK | ITKVFDFAGE | EVRVTKEVDA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TSKEAKSFLK | QTEKEKPQAL | VTSAATPPPA | GSGIKRTSGM | SSLLGKIGAK | KQKMSTLEKS |
| 250 | 260 | 270 | 280 | 290 | |
| KLDWESFKEE | EGIGEELAIH | NRGKEGYIER | KAFLERVDHR | QFEIERDLRL | SKMKP |