Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8H2D1

Entry ID Method Resolution Chain Position Source
AF-Q8H2D1-F1 Predicted AlphaFoldDB

60 variants for Q8H2D1

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_4_15342067_G_A 5 S>L No 1000Genomes
ENSVATH00547183 6 Q>L No 1000Genomes
ENSVATH06808745 20 P>A No 1000Genomes
tmp_4_15342010_C_T 24 R>K No 1000Genomes
tmp_4_15341922_A_C 27 N>K No 1000Genomes
ENSVATH00547182 44 E>K No 1000Genomes
tmp_4_15341867_C_A 46 V>L No 1000Genomes
ENSVATH02948408 47 K>Q No 1000Genomes
ENSVATH00547181 50 A>T No 1000Genomes
ENSVATH12337880 54 K>R No 1000Genomes
ENSVATH12337879 62 D>E No 1000Genomes
ENSVATH12337877 64 N>H No 1000Genomes
ENSVATH02948407 82 R>C No 1000Genomes
ENSVATH14321622 93 M>V No 1000Genomes
ENSVATH02948406 100 L>F No 1000Genomes
tmp_4_15341680_T_C 108 Q>R No 1000Genomes
ENSVATH02948405 111 Q>L No 1000Genomes
ENSVATH02948404 113 I>S No 1000Genomes
ENSVATH00547180 124 V>I No 1000Genomes
ENSVATH14321621 164 T>I No 1000Genomes
ENSVATH12337841 179 M>V No 1000Genomes
ENSVATH12337839 185 M>L No 1000Genomes
tmp_4_15341247_C_G 190 K>N No 1000Genomes
ENSVATH12337837 190 K>R No 1000Genomes
tmp_4_15341181_A_T 212 S>R No 1000Genomes
tmp_4_15341179_A_T 213 L>H No 1000Genomes
ENSVATH06808741 218 K>I No 1000Genomes
ENSVATH02948396 221 G>V No 1000Genomes
tmp_4_15341140_G_A 226 T>I No 1000Genomes
tmp_4_15341090_G_A 243 R>C No 1000Genomes
ENSVATH12337835 248 R>W No 1000Genomes
tmp_4_15340954_G_A 265 H>Y No 1000Genomes
tmp_4_15340950_A_C 266 L>R No 1000Genomes
ENSVATH00547178 267 P>A No 1000Genomes
tmp_4_15340927_T_C 274 N>D No 1000Genomes
tmp_4_15340878_A_G 290 V>A No 1000Genomes
ENSVATH02948391 305 H>Y No 1000Genomes
ENSVATH06808737 312 W>S No 1000Genomes
tmp_4_15340785_A_T 321 V>E No 1000Genomes
ENSVATH02948390 323 A>G No 1000Genomes
tmp_4_15340780_C_T 323 A>T No 1000Genomes
tmp_4_15340755_A_G 331 L>S No 1000Genomes
ENSVATH02948389 345 K>M No 1000Genomes
tmp_4_15340634_T_A 348 Q>H No 1000Genomes
tmp_4_15340633_G_A 349 P>S No 1000Genomes
ENSVATH02948386 351 F>L No 1000Genomes
ENSVATH06808736 351 F>S No 1000Genomes
ENSVATH02948384 381 M>V No 1000Genomes
tmp_4_15340531_G_A 383 P>S No 1000Genomes
ENSVATH02948383 384 E>K No 1000Genomes
ENSVATH02948382 387 K>I No 1000Genomes
ENSVATH06808735 404 S>F No 1000Genomes
ENSVATH12337773 407 K>N No 1000Genomes
tmp_4_15340419_G_C 420 T>R No 1000Genomes
ENSVATH02948381 422 H>Q No 1000Genomes
ENSVATH02948380 435 T>I No 1000Genomes
ENSVATH12337772 443 E>G No 1000Genomes
ENSVATH06808734 459 N>D No 1000Genomes
tmp_4_15340296_A_C 461 L>* No 1000Genomes
tmp_4_15340294_T_A 462 S>C No 1000Genomes

No associated diseases with Q8H2D1

3 regional properties for Q8H2D1

Type Name Position InterPro Accession
domain B3 DNA binding domain 11 - 103 IPR003340-1
domain B3 DNA binding domain 148 - 244 IPR003340-2
domain B3 DNA binding domain 248 - 346 IPR003340-3

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5N6V0 Os01g0905400 B3 domain-containing protein Os01g0905400 Oryza sativa subsp japonica (Rice) PR
Q7XS75 Os04g0346900 Putative B3 domain-containing protein Os04g0346900 Oryza sativa subsp japonica (Rice) PR
Q7XS74 Os04g0347400 Putative B3 domain-containing protein Os04g0347400 Oryza sativa subsp japonica (Rice) PR
Q9XIB4 At1g49475 B3 domain-containing protein At1g49475 Arabidopsis thaliana (Mouse-ear cress) PR
Q84J39 REM1 B3 domain-containing protein REM1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MANASQLSPT NKHFFKPLLP GFQRNLNIPV KFFSEHIEGK HEGETVKLRA DASKRTWEVK
70 80 90 100 110 120
MDGNRLTEGW KEFVEAHDLR IRDFVVFRHE GDMVFHVTAL GPSCCEIQYP QSISHEEGEE
130 140 150 160 170 180
SGEVEISERE VEENLQKEYD QSSADLNCFS QSVTHSNISN DLVTLPRDFA KRNGLDKGMH
190 200 210 220 230 240
EIVLMNEEGK SWESEVRSRM SGQVFIVGGW KSLCSENKLK GGDSCTFKLL QNAKTPVFQL
250 260 270 280 290 300
CSRIGESRFV KLTPTLNSLE IGKQHLPVSF TKGNGLIHPG EIILVDKDRV EWSMKLQVDN
310 320 330 340 350 360
RGGMHIFGGN DWKSFCAANE VGAGESLTLE LIRGGLSPLF KFFSKIEQPS FEAEDRRHKR
370 380 390 400 410 420
ARVHNGSQET DKGEPSRATK MGPELEKREK TAEKGEPSRA SNKSSGKQGN LQKTQACSVT
430 440 450 460
DHVAKVKESV VDTLTSIRRF QAELETMEQK LEDSLQEINK LS