Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8GW20

Entry ID Method Resolution Chain Position Source
AF-Q8GW20-F1 Predicted AlphaFoldDB

32 variants for Q8GW20

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_1048351_C_T 5 S>L No 1000Genomes
tmp_5_1048353_A_G 6 T>A No 1000Genomes
ENSVATH06918526 11 S>P No 1000Genomes
tmp_5_1048432_C_T 32 P>L No 1000Genomes
ENSVATH03018724 34 D>V No 1000Genomes
tmp_5_1048463_A_C 42 L>F No 1000Genomes
tmp_5_1048473_T_G 46 C>G No 1000Genomes
tmp_5_1048489_G_A 51 R>Q No 1000Genomes
tmp_5_1048496_T_A 53 F>L No 1000Genomes
ENSVATH00605350 57 G>E No 1000Genomes
tmp_5_1048552_C_G 72 A>G No 1000Genomes
ENSVATH10549707 166 F>Y No 1000Genomes
ENSVATH06918533 177 L>S No 1000Genomes
ENSVATH03018729 181 S>C No 1000Genomes
tmp_5_1049627_G_A 244 R>Q No 1000Genomes
tmp_5_1050079_A_G 284 Y>C No 1000Genomes
ENSVATH10549785 286 T>S No 1000Genomes
tmp_5_1050116_A_C 296 E>D No 1000Genomes
tmp_5_1050158_G_T 310 M>I No 1000Genomes
tmp_5_1050511_T_A 334 N>K No 1000Genomes
ENSVATH00605359 338 C>R No 1000Genomes
ENSVATH10549788 338 C>Y No 1000Genomes
tmp_5_1050570_A_G 354 E>G No 1000Genomes
tmp_5_1050774_C_T 386 A>V No 1000Genomes
tmp_5_1050818_G_T 401 V>F No 1000Genomes
ENSVATH00605361 445 I>V No 1000Genomes
ENSVATH06918549 452 I>L No 1000Genomes
ENSVATH06918553 482 D>E No 1000Genomes
ENSVATH06918552 482 D>V No 1000Genomes
tmp_5_1051792_G_A 499 D>N No 1000Genomes
ENSVATH03018743 513 D>N No 1000Genomes
tmp_5_1051838_G_A 514 R>K No 1000Genomes

No associated diseases with Q8GW20

No regional properties for Q8GW20

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8GW20

Functions

Description
EC Number
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chloroplast envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q86U28 ISCA2 Iron-sulfur cluster assembly 2 homolog, mitochondrial Homo sapiens (Human) PR
Q8LCY2 At5g03905 Iron-sulfur assembly protein IscA-like 2, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MACVSTCLIL SPRLTQVGLS SKKPFLIRLR SPVDRYSFPR MLTERCLSTR RKFNRHGIAV
70 80 90 100 110 120
VKAASLDKVS GAIKPGGLVE SDKLPTDVRK RAMDAVDECG RRVTVGDVAS RGGLKVTEAQ
130 140 150 160 170 180
TALQAIAADT DGFLEVSDEG DVLYVFPRDY RTKLAAKSLR IQIEPFLEKA KGAVDYLARV
190 200 210 220 230 240
SFGTALIASI VIVYTSIIAL LSSKSEDDNR QRRRGRSYDS GFNFYINPVD LLWYWDPNYY
250 260 270 280 290 300
NRRRAREDEG KGMNFIESVF SFVFGDGDPN QGIEEERWQM IGQYITSRGG VVAADELAPY
310 320 330 340 350 360
LDVPSSKSAM NDESYILPVL LRFDGQPELD EEGNILYCFP SLQRTASGSS RRKEYVGKWF
370 380 390 400 410 420
DWVADMEKFF KEKKWQFSKT STSERALVIG LGAVNLFGVI VLNTLLNEMS VRPGGFLTFV
430 440 450 460 470 480
KNIYPLLQIY AGSFFTIPLI RWFSIKRKNN QIENRNKARL QFARALESPD IALRRKLLSA
490 500 510 520
RDMAQKTVIG KDRIVYSTDR DMMEQNYETD EWDRRFKELE KSD