Q8BQ47
Gene name |
Cnpy4 (Prat4b) |
Protein name |
Protein canopy homolog 4 |
Names |
Protein associated with Tlr4 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:66455 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8BQ47
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8BQ47-F1 | Predicted | AlphaFoldDB |
10 variants for Q8BQ47
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3396200963 | 41 | P>L | No | EVA | |
| rs3395896281 | 42 | S>G | No | EVA | |
| rs3388783188 | 52 | M>L | No | EVA | |
| rs3388803900 | 54 | L>I | No | EVA | |
| rs256556290 | 57 | A>E | No | EVA | |
| rs253541808 | 98 | N>K | No | EVA | |
| rs3388796633 | 199 | E>D | No | EVA | |
| rs3388793706 | 206 | A>S | No | EVA | |
| rs3388793696 | 228 | E>K | No | EVA | |
| rs3388791633 | 238 | P>S | No | EVA |
No associated diseases with Q8BQ47
1 regional properties for Q8BQ47
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain | 306 - 438 | IPR032319 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| signaling receptor binding | Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of protein localization to plasma membrane | Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. |
| regulation of protein localization | Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q0P5N1 | CNPY3 | Protein canopy homolog 3 | Bos taurus (Bovine) | PR |
| Q9BT09 | CNPY3 | Protein canopy homolog 3 | Homo sapiens (Human) | PR |
| A5GFQ5 | CNPY3 | Protein canopy homolog 3 | Sus scrofa (Pig) | PR |
| A3KNS2 | cnpy3 | Protein canopy homolog 3 | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MCGLRFIMGP | VRLEILLFIL | AAYGAWAEAT | KEEEDDTERL | PSKCEVCKLL | SMELQEALSR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TGRSREVLEL | GQVLDTGKRK | RHVPYSLSET | RLEEALENLC | ERILDYNVHA | ERKGSLRYAK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GQSQTMATLK | GLVQKGVKVD | LGIPLELWDE | PSVEVTFLKK | QCETMLEEFE | DVVGDWYFHH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QEQPLQHFLC | ERHVLPASET | ACLREAWTGK | EKISDGQEEA | DDEEEEEEEE | ITKTSGNPKH |
| DPEDL |